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ONTOLOGY REPORT - ANNOTATIONS


Term:G0 to G1 transition
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Accession:GO:0045023 term browser browse the term
Definition:The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression.


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G0 to G1 transition term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:23119170 RGD:7207882 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309
JBrowse link
negative regulation of G0 to G1 transition term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAB2IP DAB2 interacting protein IEA Ensembl GO_REF:0000107 NCBI chr 9:60,725,887...60,918,242
Ensembl chr 9:60,726,809...60,918,139
JBrowse link
G FOXO4 forkhead box O4 IEA Ensembl GO_REF:0000107 NCBI chr  X:55,469,738...55,477,699
Ensembl chr  X:55,469,382...55,477,699
JBrowse link
G LOC491532 double homeobox protein 4-like protein 4 ISO (PMID:24589735) UniProtKB PMID:24589735 NCBI chr17:64,235,661...64,238,828 JBrowse link
G PPP2R5B protein phosphatase 2 regulatory subunit B'beta ISO PMID:19029245 MGI PMID:19029245 RGD:8553977 NCBI chr18:52,244,588...52,253,055
Ensembl chr18:52,244,736...52,252,237
JBrowse link
G ZNHIT1 zinc finger HIT-type containing 1 ISO (MGI:3851280|PMID:19501046) MGI PMID:19501046 MGI:3851280 NCBI chr 6:8,658,288...8,663,511
Ensembl chr 6:8,658,253...8,663,449
JBrowse link
positive regulation of G0 to G1 transition term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN2 cellular communication network factor 2 ISO RGD PMID:18613219 RGD:2314619 NCBI chr 1:25,508,082...25,511,058
Ensembl chr 1:25,507,662...25,510,145
JBrowse link
G MED1 mediator complex subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:22,989,257...23,019,350
Ensembl chr 9:22,989,301...23,019,349
JBrowse link
G ORC1 origin recognition complex subunit 1 ISO RGD PMID:18499104 RGD:9588277 NCBI chr15:8,965,339...8,995,527
Ensembl chr15:8,971,732...8,995,481
JBrowse link
G RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 IEA Ensembl GO_REF:0000107 NCBI chr27:41,885,779...41,906,252
Ensembl chr27:41,886,052...41,891,759
JBrowse link
G SOX15 SRY-box transcription factor 15 IEA Ensembl GO_REF:0000107 NCBI chr 5:32,507,869...32,509,763
Ensembl chr 5:32,508,074...32,509,333
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16186
    cellular process 15465
      cell cycle process 1161
        G0 to G1 transition 11
          negative regulation of G0 to G1 transition 5
          positive regulation of G0 to G1 transition 5
          regulation of G0 to G1 transition + 10
Path 2
Term Annotations click to browse term
  biological_process 16186
    cellular process 15465
      cell cycle 1461
        cell cycle process 1161
          G0 to G1 transition 11
            negative regulation of G0 to G1 transition 5
            positive regulation of G0 to G1 transition 5
            regulation of G0 to G1 transition + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.