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ONTOLOGY REPORT - ANNOTATIONS


Term:oxoglutarate dehydrogenase complex
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Accession:GO:0045252 term browser browse the term
Definition:A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
Comment:See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.
Synonyms:exact_synonym: dihydrolipoamide S-succinyltransferase complex


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Path 1
Term Annotations click to browse term
  cellular_component 0
    protein-containing complex 0
      tricarboxylic acid cycle enzyme complex 0
        dihydrolipoyl dehydrogenase complex 0
          oxoglutarate dehydrogenase complex 0
            cytosolic oxoglutarate dehydrogenase complex 0
            mitochondrial oxoglutarate dehydrogenase complex 0
Path 2
Term Annotations click to browse term
  cellular_component 0
    protein-containing complex 0
      catalytic complex 0
        oxidoreductase complex 0
          dihydrolipoyl dehydrogenase complex 0
            oxoglutarate dehydrogenase complex 0
              cytosolic oxoglutarate dehydrogenase complex 0
              mitochondrial oxoglutarate dehydrogenase complex 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.