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Term:proton-transporting ATP synthase complex
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Accession:GO:0045259 term browser browse the term
Definition:A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient.
Synonyms:exact_synonym: F1-F0 complex;   hydrogen-translocating F-type ATPase complex;   hydrogen-transporting ATP synthase complex
 related_synonym: proton-transporting F-type ATPase complex
 alt_id: GO:0045255


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proton-transporting ATP synthase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP5F1A ATP synthase F1 subunit alpha JBrowse link 18 46,080,248 46,104,233 RGD:2290271
G ATP5F1B ATP synthase F1 subunit beta JBrowse link 12 56,638,175 56,645,984 RGD:2290271
mitochondrial proton-transporting ATP synthase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP5F1A ATP synthase F1 subunit alpha JBrowse link 18 46,080,248 46,104,233 RGD:2290271
G ATP5F1B ATP synthase F1 subunit beta JBrowse link 12 56,638,175 56,645,984 RGD:2290271
G ATP5F1C ATP synthase F1 subunit gamma JBrowse link 10 7,788,104 7,807,801 RGD:2290271
G ATP5F1D ATP synthase F1 subunit delta JBrowse link 19 1,241,751 1,244,825 RGD:2290271
G ATP5F1E ATP synthase F1 subunit epsilon JBrowse link 20 59,025,475 59,032,335 RGD:2290271
G ATP5MC1 ATP synthase membrane subunit c locus 1 JBrowse link 17 48,892,787 48,895,871 RGD:2290271
G ATP5MD ATP synthase membrane subunit DAPIT JBrowse link 10 103,389,050 103,396,505 RGD:2290271
G ATP5ME ATP synthase membrane subunit e JBrowse link 4 672,436 674,276 RGD:2290271
G ATP5MF ATP synthase membrane subunit f JBrowse link 7 99,458,158 99,466,167 RGD:2290271
G ATP5MG ATP synthase membrane subunit g JBrowse link 11 118,401,389 118,409,847 RGD:2290271
G ATP5MPL ATP synthase membrane subunit 6.8PL JBrowse link 14 103,912,288 103,921,529 RGD:2290271
G ATP5PB ATP synthase peripheral stalk-membrane subunit b JBrowse link 1 111,449,464 111,462,773 RGD:2290271
G ATP5PD ATP synthase peripheral stalk subunit d JBrowse link 17 75,038,863 75,046,969 RGD:2290271
G ATP5PF ATP synthase peripheral stalk subunit F6 JBrowse link 21 25,724,480 25,735,654 RGD:2290271
G ATP5PO ATP synthase peripheral stalk subunit OSCP JBrowse link 21 33,903,453 33,915,804 RGD:2290271
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 JBrowse link MT 8,527 9,207 RGD:2290271
G MT-ATP8 mitochondrially encoded ATP synthase membrane subunit 8 JBrowse link MT 8,366 8,572 RGD:2290271
G PPIF peptidylprolyl isomerase F JBrowse link 10 79,347,469 79,355,334 RGD:2290271
mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP5F1A ATP synthase F1 subunit alpha JBrowse link 18 46,080,248 46,104,233 RGD:9068941
G ATP5F1B ATP synthase F1 subunit beta JBrowse link 12 56,638,175 56,645,984 RGD:9068941
G ATP5F1C ATP synthase F1 subunit gamma JBrowse link 10 7,788,104 7,807,801 RGD:2290271
G ATP5F1D ATP synthase F1 subunit delta JBrowse link 19 1,241,751 1,244,825 RGD:2290271
G ATP5F1E ATP synthase F1 subunit epsilon JBrowse link 20 59,025,475 59,032,335 RGD:2290271
G ATP5F1EP2 ATP synthase F1 subunit epsilon pseudogene 2 JBrowse link 13 27,945,206 27,945,573 RGD:2290271
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AP001267.5 novel protein RGD:2290271
G ATP5MC1 ATP synthase membrane subunit c locus 1 JBrowse link 17 48,892,787 48,895,871 RGD:2290271
G ATP5MC2 ATP synthase membrane subunit c locus 2 JBrowse link 12 53,665,160 53,677,546 RGD:2290271
G ATP5MC3 ATP synthase membrane subunit c locus 3 JBrowse link 2 175,176,258 175,181,710 RGD:2290271
G ATP5ME ATP synthase membrane subunit e JBrowse link 4 672,436 674,276 RGD:2290271
G ATP5MF ATP synthase membrane subunit f JBrowse link 7 99,458,158 99,466,167 RGD:2290271
G ATP5MG ATP synthase membrane subunit g JBrowse link 11 118,401,389 118,409,847 RGD:2290271
G ATP5MGL ATP synthase membrane subunit g like JBrowse link 22 42,639,803 42,640,601 RGD:2290271
G ATP5PB ATP synthase peripheral stalk-membrane subunit b JBrowse link 1 111,449,464 111,462,773 RGD:2290271
G ATP5PD ATP synthase peripheral stalk subunit d JBrowse link 17 75,038,863 75,046,969 RGD:2290271
G ATP5PF ATP synthase peripheral stalk subunit F6 JBrowse link 21 25,724,480 25,735,654 RGD:2290271
G ATP5PO ATP synthase peripheral stalk subunit OSCP JBrowse link 21 33,903,453 33,915,804 RGD:9068941
G MT-ATP8 mitochondrially encoded ATP synthase membrane subunit 8 JBrowse link MT 8,366 8,572 RGD:2290271
mitochondrial proton-transporting ATP synthase, catalytic core term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP5F1B ATP synthase F1 subunit beta JBrowse link 12 56,638,175 56,645,984 RGD:2290271
mitochondrial proton-transporting ATP synthase, stator stalk term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP5PD ATP synthase peripheral stalk subunit d JBrowse link 17 75,038,863 75,046,969 RGD:2290271
proton-transporting ATP synthase complex, catalytic core F(1) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP5F1A ATP synthase F1 subunit alpha JBrowse link 18 46,080,248 46,104,233 RGD:2290271
G ATP5F1B ATP synthase F1 subunit beta JBrowse link 12 56,638,175 56,645,984 RGD:2290271
G ATP5F1C ATP synthase F1 subunit gamma JBrowse link 10 7,788,104 7,807,801 RGD:9068941
G ATP5F1D ATP synthase F1 subunit delta JBrowse link 19 1,241,751 1,244,825 RGD:2290271
G ATP5F1E ATP synthase F1 subunit epsilon JBrowse link 20 59,025,475 59,032,335 RGD:9068941
proton-transporting ATP synthase complex, coupling factor F(o) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP5MC1 ATP synthase membrane subunit c locus 1 JBrowse link 17 48,892,787 48,895,871 RGD:2290271
G ATP5MC2 ATP synthase membrane subunit c locus 2 JBrowse link 12 53,665,160 53,677,546 RGD:2290271
G ATP5MC3 ATP synthase membrane subunit c locus 3 JBrowse link 2 175,176,258 175,181,710 RGD:2290271
G DMAC2L distal membrane arm assembly complex 2 like JBrowse link 14 50,311,516 50,327,957 RGD:2290271
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 JBrowse link MT 8,527 9,207 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19247
    intracellular 14988
      proton-transporting ATP synthase complex 24
        chloroplast proton-transporting ATP synthase complex + 0
        mitochondrial proton-transporting ATP synthase complex + 23
        plasma membrane proton-transporting ATP synthase complex + 0
        proton-transporting ATP synthase complex, catalytic core F(1) + 6
        proton-transporting ATP synthase complex, coupling factor F(o) + 15
Path 2
Term Annotations click to browse term
  cellular_component 19247
    cellular anatomical entity 19007
      membrane 10070
        membrane protein complex 1359
          proton-transporting two-sector ATPase complex 54
            proton-transporting ATP synthase complex 24
              chloroplast proton-transporting ATP synthase complex + 0
              mitochondrial proton-transporting ATP synthase complex + 23
              plasma membrane proton-transporting ATP synthase complex + 0
              proton-transporting ATP synthase complex, catalytic core F(1) + 6
              proton-transporting ATP synthase complex, coupling factor F(o) + 15
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.