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ONTOLOGY REPORT - ANNOTATIONS


Term:mRNA cis splicing, via spliceosome
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Accession:GO:0045292 term browser browse the term
Definition:The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.
Synonyms:exact_synonym: nuclear mRNA cis splicing, via spliceosome
 narrow_synonym: nuclear mRNA cis splicing, via U2-type spliceosome
 broad_synonym: splicing


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mRNA cis splicing, via spliceosome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cwc15 CWC15 spliceosome-associated protein JBrowse link 8 12,994,131 13,004,958 RGD:13792537
G Dcps decapping enzyme, scavenger JBrowse link 8 36,321,992 36,374,665 RGD:1600115
RGD:1624291
G Ncbp1 nuclear cap binding protein subunit 1 JBrowse link 5 61,734,118 61,767,098 RGD:1600115
G Ncbp2 nuclear cap binding protein subunit 2 JBrowse link 11 72,071,838 72,103,087 RGD:1600115
RGD:1624291
G Prpf40a pre-mRNA processing factor 40 homolog A JBrowse link 3 38,680,583 38,741,570 RGD:1600115
G Prpf40b pre-mRNA processing factor 40 homolog B JBrowse link 7 140,958,952 140,981,588 RGD:1600115
G Rbm19 RNA binding motif protein 19 JBrowse link 12 41,907,978 41,993,969 RGD:13792537
G Rbm22 RNA binding motif protein 22 JBrowse link 18 55,828,158 55,839,421 RGD:1624291
RGD:1600115
G Rbm4b RNA binding motif protein 4B JBrowse link 1 220,009,397 220,019,488 RGD:13792537
G Sart1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP JBrowse link 1 220,762,496 220,771,158 RGD:13792537
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link 10 75,334,200 75,341,197 RGD:13792537
G Srsf10 serine and arginine rich splicing factor 10 JBrowse link 5 154,205,358 154,219,550 RGD:13792537
G Srsf12 serine and arginine rich splicing factor 12 JBrowse link 5 48,456,777 48,484,017 RGD:13792537
G Srsf2 serine and arginine rich splicing factor 2 JBrowse link 10 105,792,779 105,795,986 RGD:13792537
G Srsf3 serine and arginine rich splicing factor 3 JBrowse link 20 6,288,285 6,298,218 RGD:13792537
G Srsf4 serine and arginine rich splicing factor 4 JBrowse link 5 150,032,999 150,060,769 RGD:13792537
G Srsf5 serine and arginine rich splicing factor 5 JBrowse link 6 104,611,026 104,640,033 RGD:13792537
G Srsf6 serine and arginine rich splicing factor 6 JBrowse link 3 159,305,345 159,310,668 RGD:13792537
G Srsf7 serine and arginine rich splicing factor 7 JBrowse link 6 2,879,312 2,886,505 RGD:13792537
G Srsf9 serine and arginine rich splicing factor 9 JBrowse link 12 47,039,714 47,046,022 RGD:13792537
G Wbp11 WW domain binding protein 11 JBrowse link 4 170,772,166 170,785,613 RGD:13792537
G Wbp11l1 WW domain-binding protein 11-like 1 JBrowse link 4 170,154,257 170,167,724 RGD:13792537
G Wbp4 WW domain binding protein 4 JBrowse link 15 61,745,989 61,772,516 RGD:1624291
RGD:1600115
mRNA 5'-splice site recognition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prpf39 pre-mRNA processing factor 39 JBrowse link 6 86,785,793 86,810,806 RGD:13792537
G Psip1 PC4 and SFRS1 interacting protein 1 JBrowse link 5 101,555,691 101,588,659 RGD:1624291
RGD:1600115
G Sfswap splicing factor SWAP JBrowse link 12 30,740,563 30,811,015 RGD:1624291
RGD:13792537
RGD:1600115
G Snrpc small nuclear ribonucleoprotein polypeptide C JBrowse link 20 7,409,401 7,427,581 RGD:13792537
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link 10 75,334,200 75,341,197 RGD:1624291
G Srsf12 serine and arginine rich splicing factor 12 JBrowse link 5 48,456,777 48,484,017 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    metabolic process 10729
      organic substance metabolic process 10177
        macromolecule metabolic process 8720
          gene expression 4958
            RNA processing 789
              mRNA processing 401
                mRNA splicing, via spliceosome 260
                  mRNA cis splicing, via spliceosome 27
                    cis assembly of pre-catalytic spliceosome 0
                    mRNA 5'-splice site recognition + 6
                    negative regulation of mRNA cis splicing, via spliceosome 0
                    positive regulation of mRNA cis splicing, via spliceosome 0
                    regulation of mRNA cis splicing, via spliceosome + 0
Path 2
Term Annotations click to browse term
  biological_process 18008
    metabolic process 10729
      cellular metabolic process 9809
        cellular nitrogen compound metabolic process 5698
          nucleobase-containing compound metabolic process 4896
            nucleic acid metabolic process 4447
              RNA metabolic process 3980
                RNA processing 789
                  RNA splicing 340
                    RNA splicing, via transesterification reactions 260
                      RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 260
                        mRNA splicing, via spliceosome 260
                          mRNA cis splicing, via spliceosome 27
                            cis assembly of pre-catalytic spliceosome 0
                            mRNA 5'-splice site recognition + 6
                            negative regulation of mRNA cis splicing, via spliceosome 0
                            positive regulation of mRNA cis splicing, via spliceosome 0
                            regulation of mRNA cis splicing, via spliceosome + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.