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ONTOLOGY REPORT - ANNOTATIONS


Term:carnitine biosynthetic process
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Accession:GO:0045329 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
Synonyms:exact_synonym: carnitine anabolism;   carnitine biosynthesis;   carnitine formation;   carnitine synthesis;   vitamin Bt biosynthesis;   vitamin Bt biosynthetic process


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carnitine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain ISO (PMID:16972171) RGD PMID:16972171 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 TAS
IEA
GO_REF:0000041 UniProt PMID:10702312 GO_REF:0000041, RGD:68317 NCBI chr13:85,580,828...85,597,497
Ensembl chr13:85,580,828...85,597,493
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 TAS
IBA
ISO
ISS
IEA
PMID:21873635
(PMID:20599753), (PMID:9753662)
GO_REF:0000024
GO_REF:0000041
RGD
UniProt
PMID:9753662, PMID:20599753, PMID:10526231, PMID:21873635, PMID:9753662 GO_REF:0000024, GO_REF:0000041, RGD:632240, RGD:13792537, RGD:8554503 NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
JBrowse link
G Tmlhe trimethyllysine hydroxylase, epsilon TAS
ISO
IEA
ISS
IBA
(MGI:MGI:2183690|PMID:12121276)
GO_REF:0000041
GO_REF:0000024
(PMID:15754339), (PMID:23092983)
PMID:21873635
RGD
UniProt
PMID:12121276, PMID:15754339, PMID:23092983, PMID:11431483, PMID:21873635 GO_REF:0000024, GO_REF:0000041, MGI:MGI:2183690, RGD:70558, RGD:13792537 NCBI chr20:237,461...285,125
Ensembl chr20:237,506...284,943
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      cellular metabolic process 11065
        cellular modified amino acid metabolic process 187
          amino-acid betaine metabolic process 19
            amino-acid betaine biosynthetic process 6
              carnitine biosynthetic process 4
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      organic substance metabolic process 11636
        organonitrogen compound metabolic process 7132
          organonitrogen compound biosynthetic process 2029
            cellular modified amino acid biosynthetic process 41
              amino-acid betaine biosynthetic process 6
                carnitine biosynthetic process 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.