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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of MHC class II biosynthetic process
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Accession:GO:0045347 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms:exact_synonym: down regulation of MHC class II biosynthetic process;   downregulation of MHC class II biosynthetic process;   negative regulation of MHC class II anabolism;   negative regulation of MHC class II biosynthesis;   negative regulation of MHC class II formation;   negative regulation of MHC class II synthesis;   negative regulation of major histocompatibility complex class II biosynthesis;   negative regulation of major histocompatibility complex class II biosynthetic process
 narrow_synonym: inhibition of MHC class II biosynthetic process


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negative regulation of MHC class II biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 ISO (PMID:1940799) RGD PMID:1940799 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Marchf8 membrane associated ring-CH-type finger 8 ISO (MGI:MGI:3785681|PMID:16785530) RGD PMID:16785530 MGI:MGI:3785681 NCBI chr 4:148,285,467...148,398,148
Ensembl chr 4:148,286,853...148,398,148
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 ISO (MGI:MGI:2180954|PMID:12047746) RGD PMID:12047746 MGI:MGI:2180954 NCBI chr 5:57,290,916...57,348,720
Ensembl chr 5:57,291,156...57,348,720
JBrowse link
G Pf4 platelet factor 4 ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Spi1 Spi-1 proto-oncogene ISO (MGI:MGI:4942273|PMID:7592651) RGD PMID:7592651 MGI:MGI:4942273 NCBI chr 3:79,918,127...79,937,708
Ensembl chr 3:79,918,969...79,938,301
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 ISO (PMID:20937824) RGD PMID:20937824 NCBI chr18:30,779,149...30,781,297
Ensembl chr18:30,779,150...30,781,292
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    negative regulation of biological process 5686
      negative regulation of metabolic process 3307
        negative regulation of biosynthetic process 1702
          negative regulation of macromolecule biosynthetic process 1598
            negative regulation of MHC class II biosynthetic process 6
Path 2
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological process 13075
        regulation of metabolic process 6985
          regulation of macromolecule metabolic process 6491
            regulation of macromolecule biosynthetic process 3857
              negative regulation of macromolecule biosynthetic process 1598
                negative regulation of MHC class II biosynthetic process 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.