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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of MHC class II biosynthetic process
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Accession:GO:0045348 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms:exact_synonym: positive regulation of MHC class II anabolism;   positive regulation of MHC class II biosynthesis;   positive regulation of MHC class II formation;   positive regulation of MHC class II synthesis;   positive regulation of major histocompatibility complex class II biosynthesis;   positive regulation of major histocompatibility complex class II biosynthetic process;   up regulation of MHC class II biosynthetic process;   upregulation of MHC class II biosynthetic process
 narrow_synonym: activation of MHC class II biosynthetic process;   stimulation of MHC class II biosynthetic process


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positive regulation of MHC class II biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZU1 azurocidin 1 ISO (PMID:12465046) UniProtKB PMID:12465046 NCBI chr19:300,318...304,730
Ensembl chr19:797,038...800,691
JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:18262271 RGD:2313421 NCBI chr  X:125,776,138...125,788,820
Ensembl chr  X:136,042,849...136,058,202
JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 ISO (PMID:29020624) ARUK-UCL PMID:29020624 NCBI chr17:24,285,069...24,289,311
Ensembl chr17:24,577,537...24,579,232
JBrowse link
G CIITA class II major histocompatibility complex transactivator ISO RGD PMID:11071855, PMID:11477547 RGD:632487, RGD:632488 NCBI chr16:9,819,440...9,885,379
Ensembl chr16:11,041,434...11,090,485
JBrowse link
G IFNG interferon gamma ISO (MGI:5776417|PMID:26227742)
(MGI:3033882|PMID:11027433), (MGI:4942276|PMID:2502420), (MGI:4942277|PMID:2493384), (MGI:4943415|PMID:1845803)
RGD
ARUK-UCL
BHF-UCL
PMID:1845803, PMID:2493384, PMID:2502420, PMID:3127329, PMID:11027433, PMID:26227742 MGI:3033882, MGI:4942276, MGI:4942277, MGI:4943415, MGI:5776417, RGD:8547557 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G IL10 interleukin 10 ISO (MGI:3033882|PMID:11027433) MGI PMID:11027433 MGI:3033882 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL33 interleukin 33 ISO (MGI:6414704|PMID:26936882) ARUK-UCL PMID:26936882 MGI:6414704 NCBI chr 9:6,027,014...6,069,540
Ensembl chr 9:6,234,178...6,248,624
JBrowse link
G IL4 interleukin 4 ISO (MGI:2178646|PMID:10549626), (MGI:3033882|PMID:11027433) MGI PMID:10549626, PMID:11027433 MGI:2178646, MGI:3033882 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G JAK2 Janus kinase 2 ISO (MGI:5776417|PMID:26227742) ARUK-UCL PMID:26227742 MGI:5776417 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626
JBrowse link
G SIRT1 sirtuin 1 ISO (PMID:21890893) UniProtKB PMID:21890893 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G TLR4 toll like receptor 4 ISO (MGI:2178646|PMID:10549626) MGI PMID:10549626 MGI:2178646 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711
JBrowse link
G TMEM106A transmembrane protein 106A ISO (MGI:6216178|PMID:26215746) UniProt PMID:26215746 MGI:6216178 NCBI chr17:14,111,300...14,119,486
Ensembl chr17:14,343,676...14,351,146
JBrowse link
G XBP1 X-box binding protein 1 ISO (PMID:1903538) UniProtKB PMID:1903538 NCBI chr22:9,863,479...9,869,491 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12566
    positive regulation of biological process 5615
      positive regulation of metabolic process 3455
        positive regulation of biosynthetic process 1797
          positive regulation of macromolecule biosynthetic process 1651
            positive regulation of MHC class II biosynthetic process 13
Path 2
Term Annotations click to browse term
  biological_process 12566
    biological regulation 9172
      regulation of biological process 8675
        regulation of metabolic process 5279
          regulation of macromolecule metabolic process 4855
            regulation of macromolecule biosynthetic process 2783
              positive regulation of macromolecule biosynthetic process 1651
                positive regulation of MHC class II biosynthetic process 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.