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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of MHC class II biosynthetic process
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Accession:GO:0045348 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms:exact_synonym: positive regulation of MHC class II anabolism;   positive regulation of MHC class II biosynthesis;   positive regulation of MHC class II formation;   positive regulation of MHC class II synthesis;   positive regulation of major histocompatibility complex class II biosynthesis;   positive regulation of major histocompatibility complex class II biosynthetic process;   up regulation of MHC class II biosynthetic process;   upregulation of MHC class II biosynthetic process
 narrow_synonym: activation of MHC class II biosynthetic process;   stimulation of MHC class II biosynthetic process


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positive regulation of MHC class II biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40lg CD40 ligand ISO RGD PMID:18262271 RGD:2313421 NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746
JBrowse link
G Cdk5r1 cyclin dependent kinase 5 regulatory subunit 1 ISO (PMID:29020624) ARUK-UCL PMID:29020624 NCBI chrNW_004955481:7,408,089...7,411,813
Ensembl chrNW_004955481:7,408,205...7,409,128
JBrowse link
G Ciita class II major histocompatibility complex transactivator ISO RGD PMID:11071855, PMID:11477547 RGD:632487, RGD:632488 NCBI chrNW_004955442:7,600,903...7,647,619
Ensembl chrNW_004955442:7,603,893...7,647,624
JBrowse link
G Ifng interferon gamma ISO (MGI:3033882|PMID:11027433), (MGI:4942276|PMID:2502420), (MGI:4942277|PMID:2493384), (MGI:4943415|PMID:1845803)
(MGI:5776417|PMID:26227742)
RGD
BHF-UCL
ARUK-UCL
PMID:1845803, PMID:2493384, PMID:2502420, PMID:3127329, PMID:11027433, PMID:26227742 MGI:3033882, MGI:4942276, MGI:4942277, MGI:4943415, MGI:5776417, RGD:8547557 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link
G Il10 interleukin 10 ISO (MGI:3033882|PMID:11027433) MGI PMID:11027433 MGI:3033882 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il33 interleukin 33 ISO (MGI:6414704|PMID:26936882) ARUK-UCL PMID:26936882 MGI:6414704 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948
JBrowse link
G Il4 interleukin 4 ISO (MGI:2178646|PMID:10549626), (MGI:3033882|PMID:11027433) MGI PMID:10549626, PMID:11027433 MGI:2178646, MGI:3033882 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Jak2 Janus kinase 2 ISO (MGI:5776417|PMID:26227742) ARUK-UCL PMID:26227742 MGI:5776417 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
JBrowse link
G Sirt1 sirtuin 1 ISO (PMID:21890893) UniProtKB PMID:21890893 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663
JBrowse link
G Tlr4 toll like receptor 4 ISO (MGI:2178646|PMID:10549626) MGI PMID:10549626 MGI:2178646 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
JBrowse link
G Tmem106a transmembrane protein 106A ISO (MGI:6216178|PMID:26215746) UniProt PMID:26215746 MGI:6216178 NCBI chrNW_004955451:16,896,151...16,902,117
Ensembl chrNW_004955451:16,897,541...16,901,092
JBrowse link
G Xbp1 X-box binding protein 1 ISO (PMID:1903538) UniProtKB PMID:1903538 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11892
    positive regulation of biological process 5386
      positive regulation of metabolic process 3311
        positive regulation of biosynthetic process 1755
          positive regulation of macromolecule biosynthetic process 1612
            positive regulation of MHC class II biosynthetic process 12
Path 2
Term Annotations click to browse term
  biological_process 11892
    biological regulation 8725
      regulation of biological process 8270
        regulation of metabolic process 5040
          regulation of macromolecule metabolic process 4632
            regulation of macromolecule biosynthetic process 2681
              positive regulation of macromolecule biosynthetic process 1612
                positive regulation of MHC class II biosynthetic process 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.