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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of MHC class II biosynthetic process
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Accession:GO:0045348 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms:exact_synonym: positive regulation of MHC class II anabolism;   positive regulation of MHC class II biosynthesis;   positive regulation of MHC class II formation;   positive regulation of MHC class II synthesis;   positive regulation of major histocompatibility complex class II biosynthesis;   positive regulation of major histocompatibility complex class II biosynthetic process;   up regulation of MHC class II biosynthetic process;   upregulation of MHC class II biosynthetic process
 narrow_synonym: activation of MHC class II biosynthetic process;   stimulation of MHC class II biosynthetic process


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positive regulation of MHC class II biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD40LG CD40 ligand ISO RGD PMID:18262271 RGD:2313421 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 ISO (PMID:29020624) ARUK-UCL PMID:29020624 NCBI chr 9:40,481,111...40,502,689
Ensembl chr 9:40,501,646...40,502,569
JBrowse link
G CIITA class II major histocompatibility complex transactivator IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:31,774,486...31,837,025
Ensembl chr 6:31,774,609...31,836,820
JBrowse link
G IFNG interferon gamma ISO (MGI:5776417|PMID:26227742)
(MGI:3033882|PMID:11027433), (MGI:4942276|PMID:2502420), (MGI:4942277|PMID:2493384), (MGI:4943415|PMID:1845803)
RGD
ARUK-UCL
BHF-UCL
PMID:1845803, PMID:2493384, PMID:2502420, PMID:3127329, PMID:11027433, PMID:26227742 MGI:3033882, MGI:4942276, MGI:4942277, MGI:4943415, MGI:5776417, RGD:8547557 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IL10 interleukin 10 IEA Ensembl GO_REF:0000107 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL33 interleukin 33 ISO (MGI:6414704|PMID:26936882) ARUK-UCL PMID:26936882 MGI:6414704 NCBI chr11:27,219,878...27,256,723
Ensembl chr11:27,219,878...27,256,721
JBrowse link
G IL4 interleukin 4 ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G JAK2 Janus kinase 2 ISO (MGI:5776417|PMID:26227742) ARUK-UCL PMID:26227742 MGI:5776417 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997
JBrowse link
G SIRT1 sirtuin 1 ISO (PMID:21890893) UniProtKB PMID:21890893 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279
JBrowse link
G TLR4 toll like receptor 4 IEA Ensembl GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165
JBrowse link
G TMEM106A transmembrane protein 106A IEA Ensembl GO_REF:0000107 NCBI chr 9:19,917,591...19,926,578
Ensembl chr 9:19,915,973...19,958,789
JBrowse link
G XBP1 X-box binding protein 1 ISO (PMID:1903538) UniProtKB PMID:1903538 NCBI chr26:22,162,675...22,168,149 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16190
    positive regulation of biological process 6163
      positive regulation of metabolic process 3826
        positive regulation of biosynthetic process 2028
          positive regulation of macromolecule biosynthetic process 1871
            positive regulation of MHC class II biosynthetic process 12
Path 2
Term Annotations click to browse term
  biological_process 16190
    biological regulation 11558
      regulation of biological process 10960
        regulation of metabolic process 6410
          regulation of macromolecule metabolic process 5943
            regulation of macromolecule biosynthetic process 3510
              positive regulation of macromolecule biosynthetic process 1871
                positive regulation of MHC class II biosynthetic process 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.