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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of MHC class II biosynthetic process
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Accession:GO:0045348 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms:exact_synonym: positive regulation of MHC class II anabolism;   positive regulation of MHC class II biosynthesis;   positive regulation of MHC class II formation;   positive regulation of MHC class II synthesis;   positive regulation of major histocompatibility complex class II biosynthesis;   positive regulation of major histocompatibility complex class II biosynthetic process;   up regulation of MHC class II biosynthetic process;   upregulation of MHC class II biosynthetic process
 narrow_synonym: activation of MHC class II biosynthetic process;   stimulation of MHC class II biosynthetic process


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positive regulation of MHC class II biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZU1 azurocidin 1 IEP (PMID:12465046) UniProtKB PMID:12465046 NCBI chr19:827,837...832,018
Ensembl chr19:825,097...832,018
JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:18262271 RGD:2313421 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 IDA (PMID:29020624) ARUK-UCL PMID:29020624 NCBI chr17:32,485,028...32,491,256
Ensembl chr17:32,486,993...32,491,253
JBrowse link
G CIITA class II major histocompatibility complex transactivator IC
IBA
IEA
(PMID:9171108)
(PMID:21873635)
BHF-UCL
GO_Central
Ensembl
PMID:9171108, PMID:21873635 GO_REF:0000107 NCBI chr16:10,866,208...10,941,562
Ensembl chr16:10,866,222...10,943,021
JBrowse link
G IFNG interferon gamma ISS ARUK-UCL GO_REF:0000024 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL10 interleukin 10 IEA Ensembl GO_REF:0000107 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL33 interleukin 33 IEA Ensembl GO_REF:0000107 NCBI chr 9:6,214,591...6,257,983
Ensembl chr 9:6,215,786...6,257,983
JBrowse link
G IL4 interleukin 4 ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G JAK2 Janus kinase 2 ISS ARUK-UCL GO_REF:0000024 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,128,183
Ensembl chr 9:4,984,390...5,128,183
JBrowse link
G SIRT1 sirtuin 1 IDA (PMID:21890893) UniProtKB PMID:21890893 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G TLR4 toll like receptor 4 IEA Ensembl GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TMEM106A transmembrane protein 106A ISS UniProt GO_REF:0000024 NCBI chr17:43,211,875...43,220,041
Ensembl chr17:43,211,835...43,220,041
JBrowse link
G XBP1 X-box binding protein 1 IMP (PMID:1903538) UniProtKB PMID:1903538 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18672
    positive regulation of biological process 6969
      positive regulation of metabolic process 4219
        positive regulation of biosynthetic process 2218
          positive regulation of macromolecule biosynthetic process 2050
            positive regulation of MHC class II biosynthetic process 13
Path 2
Term Annotations click to browse term
  biological_process 18672
    biological regulation 13310
      regulation of biological process 12642
        regulation of metabolic process 7546
          regulation of macromolecule metabolic process 6987
            regulation of macromolecule biosynthetic process 4237
              positive regulation of macromolecule biosynthetic process 2050
                positive regulation of MHC class II biosynthetic process 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.