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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of MHC class II biosynthetic process
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Accession:GO:0045348 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms:exact_synonym: positive regulation of MHC class II anabolism;   positive regulation of MHC class II biosynthesis;   positive regulation of MHC class II formation;   positive regulation of MHC class II synthesis;   positive regulation of major histocompatibility complex class II biosynthesis;   positive regulation of major histocompatibility complex class II biosynthetic process;   up regulation of MHC class II biosynthetic process;   upregulation of MHC class II biosynthetic process
 narrow_synonym: activation of MHC class II biosynthetic process;   stimulation of MHC class II biosynthetic process


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positive regulation of MHC class II biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40lg CD40 ligand ISO MGI GO_REF:0000096, MGI:4417868 NCBI chr  X:57,212,143...57,224,042
Ensembl chr  X:57,212,143...57,224,042
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr11:80,477,023...80,481,184
Ensembl chr11:80,477,023...80,481,184
JBrowse link
G Ciita class II transactivator IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096, MGI:4417868, MGI:6201960 NCBI chr16:10,480,014...10,531,064
Ensembl chr16:10,480,059...10,528,418
JBrowse link
G Ifng interferon gamma IGI
IDA
(MGI:5776417|PMID:26227742)
(MGI:3033882|PMID:11027433), (MGI:4942276|PMID:2502420), (MGI:4942277|PMID:2493384), (MGI:4943415|PMID:1845803)
ARUK-UCL
BHF-UCL
PMID:1845803, PMID:2493384, PMID:2502420, PMID:11027433, PMID:26227742 MGI:3033882, MGI:4942276, MGI:4942277, MGI:4943415, MGI:5776417 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Il10 interleukin 10 IDA (MGI:3033882|PMID:11027433) MGI PMID:11027433 MGI:3033882 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il33 interleukin 33 IDA (MGI:6414704|PMID:26936882) ARUK-UCL PMID:26936882 MGI:6414704 NCBI chr19:29,925,113...29,960,718
Ensembl chr19:29,925,114...29,960,718
JBrowse link
G Il4 interleukin 4 IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:2178646|PMID:10549626), (MGI:3033882|PMID:11027433)
GO_Central
MGI
PMID:10549626, PMID:11027433, PMID:21873635 MGI:2178646, MGI:3033882, MGI:6201960 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Jak2 Janus kinase 2 IGI (MGI:5776417|PMID:26227742) ARUK-UCL PMID:26227742 MGI:5776417 NCBI chr19:29,251,803...29,313,095
Ensembl chr19:29,251,828...29,313,080
JBrowse link
G Sirt1 sirtuin 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr10:63,319,005...63,339,035
Ensembl chr10:63,319,005...63,381,704
JBrowse link
G Tlr4 toll-like receptor 4 IMP (MGI:2178646|PMID:10549626) MGI PMID:10549626 MGI:2178646 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
G Tmem106a transmembrane protein 106A IDA (MGI:6216178|PMID:26215746) UniProt PMID:26215746 MGI:6216178 NCBI chr11:101,582,242...101,591,788
Ensembl chr11:101,582,242...101,591,788
JBrowse link
G Xbp1 X-box binding protein 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr11:5,520,641...5,525,993
Ensembl chr11:5,520,659...5,525,893
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23386
    positive regulation of biological process 6540
      positive regulation of metabolic process 3872
        positive regulation of biosynthetic process 1966
          positive regulation of macromolecule biosynthetic process 1805
            positive regulation of MHC class II biosynthetic process 12
Path 2
Term Annotations click to browse term
  biological_process 23386
    biological regulation 13124
      regulation of biological process 12484
        regulation of metabolic process 6910
          regulation of macromolecule metabolic process 6431
            regulation of macromolecule biosynthetic process 3780
              positive regulation of macromolecule biosynthetic process 1805
                positive regulation of MHC class II biosynthetic process 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.