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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of MHC class II biosynthetic process
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Accession:GO:0045348 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms:exact_synonym: positive regulation of MHC class II anabolism;   positive regulation of MHC class II biosynthesis;   positive regulation of MHC class II formation;   positive regulation of MHC class II synthesis;   positive regulation of major histocompatibility complex class II biosynthesis;   positive regulation of major histocompatibility complex class II biosynthetic process;   up regulation of MHC class II biosynthetic process;   upregulation of MHC class II biosynthetic process
 narrow_synonym: activation of MHC class II biosynthetic process;   stimulation of MHC class II biosynthetic process


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positive regulation of MHC class II biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZU1 azurocidin 1 ISS UniProt GO_REF:0000024 NCBI chr 2:77,530,692...77,533,880
Ensembl chr 2:77,530,695...77,533,643
JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:18262271 RGD:2313421 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,711
JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 ISO (PMID:29020624) ARUK-UCL PMID:29020624 NCBI chr12:42,456,063...42,494,494
Ensembl chr12:42,493,321...42,494,659
JBrowse link
G CIITA class II major histocompatibility complex transactivator IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:32,171,706...32,230,775
Ensembl chr 3:32,172,214...32,230,780
JBrowse link
G IFNG interferon gamma ISO (MGI:3033882|PMID:11027433), (MGI:4942276|PMID:2502420), (MGI:4942277|PMID:2493384), (MGI:4943415|PMID:1845803)
(MGI:5776417|PMID:26227742)
RGD
BHF-UCL
ARUK-UCL
PMID:1845803, PMID:2493384, PMID:2502420, PMID:3127329, PMID:11027433, PMID:26227742 MGI:3033882, MGI:4942276, MGI:4942277, MGI:4943415, MGI:5776417, RGD:8547557 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G IL10 interleukin 10 IEA Ensembl GO_REF:0000107 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL33 interleukin 33 ISO (MGI:6414704|PMID:26936882) ARUK-UCL PMID:26936882 MGI:6414704 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,435...215,941,840
JBrowse link
G IL4 interleukin 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G JAK2 Janus kinase 2 ISO (MGI:5776417|PMID:26227742) ARUK-UCL PMID:26227742 MGI:5776417 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,686...217,002,148
JBrowse link
G SIRT1 sirtuin 1 IEA Ensembl GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,157...71,123,299
JBrowse link
G TLR4 toll like receptor 4 IEA Ensembl GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
G TMEM106A transmembrane protein 106A IEA Ensembl GO_REF:0000107 NCBI chr12:19,747,346...19,755,586
Ensembl chr12:19,745,780...19,755,521
JBrowse link
G XBP1 X-box binding protein 1 IEA Ensembl GO_REF:0000107 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,017,036
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16548
    positive regulation of biological process 6171
      positive regulation of metabolic process 3845
        positive regulation of biosynthetic process 2039
          positive regulation of macromolecule biosynthetic process 1883
            positive regulation of MHC class II biosynthetic process 13
Path 2
Term Annotations click to browse term
  biological_process 16548
    biological regulation 12014
      regulation of biological process 11423
        regulation of metabolic process 6436
          regulation of macromolecule metabolic process 5968
            regulation of macromolecule biosynthetic process 3543
              positive regulation of macromolecule biosynthetic process 1883
                positive regulation of MHC class II biosynthetic process 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.