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ONTOLOGY REPORT - ANNOTATIONS


Term:type I interferon biosynthetic process
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Accession:GO:0045351 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any type I interferon. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Synonyms:exact_synonym: type I interferon anabolism;   type I interferon biosynthesis;   type I interferon formation;   type I interferon synthesis


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type I interferon biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifnar1 interferon alpha and beta receptor subunit 1 JBrowse link 11 31,640,407 31,666,839 RGD:1624291
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:1624291
RGD:1600115
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:1624291
RGD:1600115
G Irf9 interferon regulatory factor 9 JBrowse link 15 34,282,936 34,288,981 RGD:1624291
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1624291
RGD:1600115
negative regulation of interferon-alpha biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nmi N-myc (and STAT) interactor JBrowse link 3 37,458,891 37,480,984 RGD:1624291
negative regulation of interferon-beta biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crebbp CREB binding protein JBrowse link 10 11,590,994 11,721,039 RGD:1624291
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:1624291
G Nmi N-myc (and STAT) interactor JBrowse link 3 37,458,891 37,480,984 RGD:1624291
positive regulation of interferon-alpha biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
RGD:1600115
G Tlr7 toll-like receptor 7 JBrowse link X 28,486,836 28,513,004 RGD:1624291
RGD:1600115
G Tlr8 toll-like receptor 8 JBrowse link X 28,539,158 28,562,803 RGD:1624291
RGD:1600115
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
positive regulation of interferon-beta biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tbk1 TANK-binding kinase 1 JBrowse link 7 63,655,247 63,687,978 RGD:1624291
RGD:1600115
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
RGD:1600115
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Tlr7 toll-like receptor 7 JBrowse link X 28,486,836 28,513,004 RGD:1624291
RGD:13792537
G Tlr8 toll-like receptor 8 JBrowse link X 28,539,158 28,562,803 RGD:1624291
RGD:13792537
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    multicellular organismal process 8585
      cytokine production 783
        cytokine biosynthetic process 116
          type I interferon biosynthetic process 14
            interferon-alpha biosynthetic process + 5
            interferon-beta biosynthetic process + 10
Path 2
Term Annotations click to browse term
  biological_process 18008
    metabolic process 10729
      organic substance metabolic process 10177
        organonitrogen compound metabolic process 6369
          protein metabolic process 5543
            cytokine metabolic process 120
              cytokine biosynthetic process 116
                type I interferon biosynthetic process 14
                  interferon-alpha biosynthetic process + 5
                  interferon-beta biosynthetic process + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.