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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of interleukin-6 biosynthetic process
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Accession:GO:0045409 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
Synonyms:exact_synonym: down regulation of interleukin-6 biosynthetic process;   downregulation of interleukin-6 biosynthetic process;   negative regulation of IL-6 biosynthesis;   negative regulation of IL-6 biosynthetic process;   negative regulation of interleukin-6 anabolism;   negative regulation of interleukin-6 biosynthesis;   negative regulation of interleukin-6 formation;   negative regulation of interleukin-6 synthesis
 narrow_synonym: inhibition of interleukin-6 biosynthetic process


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negative regulation of interleukin-6 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:1624291
RGD:1600115
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:1624291
RGD:1600115
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 9 94,745,220 94,850,778 RGD:1624291
RGD:1600115
G Muc16 mucin 16, cell surface associated JBrowse link 8 18,438,838 18,639,777 RGD:1624291
G Nlrp12 NLR family, pyrin domain containing 12 JBrowse link 1 64,506,750 64,543,908 RGD:1624291
RGD:13792537
G Prg4 proteoglycan 4 JBrowse link 13 67,672,588 67,688,902 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    multicellular organismal process 8585
      cytokine production 783
        negative regulation of cytokine production 271
          negative regulation of interleukin-6 production 50
            negative regulation of interleukin-6 biosynthetic process 7
Path 2
Term Annotations click to browse term
  biological_process 18008
    metabolic process 10729
      organic substance metabolic process 10177
        macromolecule metabolic process 8720
          protein metabolic process 5543
            cytokine metabolic process 120
              cytokine biosynthetic process 116
                regulation of cytokine biosynthetic process 105
                  negative regulation of cytokine biosynthetic process 31
                    negative regulation of interleukin-6 biosynthetic process 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.