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ONTOLOGY REPORT - ANNOTATIONS


Term:myoblast differentiation
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Accession:GO:0045445 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
Synonyms:exact_synonym: myoblast cell differentiation


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myoblast differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asb2 ankyrin repeat and SOCS box-containing 2 JBrowse link 6 127,212,325 127,248,451 RGD:1624291
G Cast calpastatin JBrowse link 2 1,452,111 1,561,669 RGD:5683868
G Csrp2 cysteine and glycine-rich protein 2 JBrowse link 7 53,630,675 53,649,309 RGD:61565
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1599634
G Ddx17 DEAD-box helicase 17 JBrowse link 7 120,761,843 120,765,012 RGD:1624291
G Ddx5 DEAD-box helicase 5 JBrowse link 10 94,979,759 94,988,461 RGD:1624291
G Dtymk deoxythymidylate kinase JBrowse link 9 100,921,565 100,930,399 RGD:2317229
G Fgf6 fibroblast growth factor 6 JBrowse link 4 159,563,798 159,572,333 RGD:1624291
RGD:1600115
G Hinfp histone H4 transcription factor JBrowse link 8 48,626,398 48,638,012 RGD:1624291
RGD:1600115
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:5508688
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
RGD:1600115
G Kcnab1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 JBrowse link 2 155,555,798 156,011,438 RGD:9743957
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 JBrowse link 5 169,570,327 169,658,875 RGD:9743957
G Lgals1 galectin 1 JBrowse link 7 120,153,184 120,156,290 RGD:1624291
RGD:1600115
G Maml1 mastermind-like transcriptional coactivator 1 JBrowse link 10 35,765,196 35,801,375 RGD:1624291
G Mapk12 mitogen-activated protein kinase 12 JBrowse link 7 130,109,214 130,120,918 RGD:1624291
RGD:1600115
G Mbnl1 muscleblind-like splicing regulator 1 JBrowse link 2 150,698,248 150,867,791 RGD:1624291
G Myod1 myogenic differentiation 1 JBrowse link 1 102,396,538 102,399,248 RGD:8554211
RGD:1624291
G Myog myogenin JBrowse link 13 51,126,459 51,129,048 RGD:9686129
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:10047212
G Plekhm3 pleckstrin homology domain containing M3 JBrowse link 9 71,492,665 71,651,529 RGD:1600115
RGD:1624291
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:1624291
RGD:1600115
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:1600115
RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
cardiac muscle cell myoblast differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
RGD:1600115
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:1624291
RGD:1600115
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:1624291
RGD:1600115
myoblast development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sdc1 syndecan 1 JBrowse link 6 33,885,576 33,908,038 RGD:1624291
RGD:1600115
G Sox15 SRY-box transcription factor 15 JBrowse link 10 56,260,514 56,263,503 RGD:1624291
myoblast differentiation involved in skeletal muscle regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:1624291
G Mir489 microRNA 489 JBrowse link 4 28,659,523 28,659,628 RGD:1624291
G Wnt10b Wnt family member 10B JBrowse link 7 140,448,284 140,466,159 RGD:1624291
RGD:1600115
myoblast fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:1624291
RGD:1600115
G Pitx1 paired-like homeodomain 1 JBrowse link 17 8,873,184 8,884,428 RGD:1624291
RGD:1600115
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:1624291
myoblast fate determination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myod1 myogenic differentiation 1 JBrowse link 1 102,396,538 102,399,248 RGD:1624291
RGD:8554648
RGD:1600115
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prickle1 prickle planar cell polarity protein 1 JBrowse link 7 134,702,964 134,799,437 RGD:1600115
RGD:1624291
negative regulation of myoblast differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd2 ankyrin repeat domain 2 JBrowse link 1 261,281,859 261,291,307 RGD:1624291
RGD:1600115
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Ccl17 C-C motif chemokine ligand 17 JBrowse link 19 10,619,220 10,620,671 RGD:1624291
G Cmtm5 CKLF-like MARVEL transmembrane domain containing 5 JBrowse link 15 33,600,016 33,602,839 RGD:1624291
RGD:1600115
G Csrp3 cysteine and glycine rich protein 3 JBrowse link 1 104,147,205 104,166,389 RGD:1624291
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:1624291
G Cxcl14 C-X-C motif chemokine ligand 14 JBrowse link 17 9,109,731 9,117,754 RGD:1624291
RGD:1600115
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:1600115
RGD:1624291
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1600115
RGD:1624291
G Eid2b EP300 interacting inhibitor of differentiation 2B JBrowse link 1 85,508,397 85,510,131 RGD:1624291
RGD:1600115
G Gdf3 growth differentiation factor 3 JBrowse link 4 155,417,667 155,422,014 RGD:1624291
RGD:1600115
G Id3 inhibitor of DNA binding 3, HLH protein JBrowse link 5 154,489,603 154,491,172 RGD:1624291
RGD:1600115
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:1624291
RGD:1600115
G Il36g interleukin 36, gamma JBrowse link 3 1,285,658 1,291,836 RGD:1624291
G Mbnl3 muscleblind-like splicing regulator 3 JBrowse link X 138,378,674 138,473,365 RGD:1624291
RGD:1600115
G Mkx mohawk homeobox JBrowse link 17 60,537,615 60,553,284 RGD:1624291
G Mstn myostatin JBrowse link 9 53,310,977 53,315,804 RGD:1624291
RGD:1600115
G Nmrk2 nicotinamide riboside kinase 2 JBrowse link 7 11,382,966 11,386,170 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Ppard peroxisome proliferator-activated receptor delta JBrowse link 20 7,818,289 7,883,482 RGD:1600115
RGD:1624291
G Sostdc1 sclerostin domain containing 1 JBrowse link 6 55,812,820 55,816,994 RGD:1624291
RGD:1600115
G Sox8 SRY-box transcription factor 8 JBrowse link 10 14,932,348 14,937,336 RGD:1624291
RGD:1600115
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
G Sra1 steroid receptor RNA activator 1 JBrowse link 18 29,494,004 29,497,232 RGD:1600115
RGD:1624291
G Tbx3 T-box transcription factor 3 JBrowse link 12 42,479,518 42,494,588 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Zfhx3 zinc finger homeobox 3 JBrowse link 19 42,753,983 42,925,794 RGD:1624291
positive regulation of myoblast differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akirin1 akirin 1 JBrowse link 5 141,415,226 141,430,627 RGD:1600115
RGD:1624291
G Boc BOC cell adhesion associated, oncogene regulated JBrowse link 11 61,084,216 61,159,220 RGD:1624291
RGD:1600115
G Btg1 BTG anti-proliferation factor 1 JBrowse link 7 37,812,831 37,815,088 RGD:1624291
RGD:1600115
G Cdon cell adhesion associated, oncogene regulated JBrowse link 8 36,625,757 36,712,091 RGD:1600115
G Csrp3 cysteine and glycine rich protein 3 JBrowse link 1 104,147,205 104,166,389 RGD:1624291
G Cxcl9 C-X-C motif chemokine ligand 9 JBrowse link 14 17,228,832 17,233,743 RGD:1624291
RGD:1600115
G Flt3lg fms-related tyrosine kinase 3 ligand JBrowse link 1 101,126,006 101,131,413 RGD:1624291
RGD:1600115
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor JBrowse link 1 264,309,214 264,319,269 RGD:1624291
RGD:1600115
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:2316802
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:1600115
RGD:1624291
G Ilk integrin-linked kinase JBrowse link 1 170,578,941 170,585,192 RGD:2302089
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:1624291
RGD:1600115
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:1600115
RGD:1624291
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1624291
RGD:1600115
G Myf5 myogenic factor 5 JBrowse link 7 49,729,533 49,732,974 RGD:13792537
G Myf6 myogenic factor 6 JBrowse link 7 49,739,643 49,741,490 RGD:13792537
G Myod1 myogenic differentiation 1 JBrowse link 1 102,396,538 102,399,248 RGD:13792537
G Myog myogenin JBrowse link 13 51,126,459 51,129,048 RGD:1624291
RGD:13792537
RGD:1600115
G Neu2 neuraminidase 2 JBrowse link 9 94,702,095 94,724,903 RGD:2316560
G Nr2c2 nuclear receptor subfamily 2, group C, member 2 JBrowse link 4 124,005,287 124,030,349 RGD:1624291
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:1625263
G Plcb1 phospholipase C beta 1 JBrowse link 3 127,721,244 128,419,565 RGD:1624291
RGD:1600115
G Ranbp3l RAN binding protein 3-like JBrowse link 2 58,221,773 58,458,072 RGD:1624291
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 17 42,324,594 42,549,907 RGD:1624291
RGD:1600115
G Smyd1 SET and MYND domain containing 1 JBrowse link 4 99,071,122 99,125,143 RGD:1624291
RGD:1600115
G Tnfsf14 TNF superfamily member 14 JBrowse link 9 9,761,363 9,765,461 RGD:1624291
RGD:1600115
G Zfhx3 zinc finger homeobox 3 JBrowse link 19 42,753,983 42,925,794 RGD:1624291
positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
RGD:1600115
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1624291
RGD:1600115
G Srf serum response factor JBrowse link 9 16,737,637 16,747,226 RGD:1624291
RGD:1600115
G Tbxt T-box transcription factor T JBrowse link 1 52,887,067 52,900,691 RGD:1624291
RGD:1600115
regulation of myoblast differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Capn3 calpain 3 JBrowse link 3 112,227,486 112,278,408 RGD:1600115
RGD:1624291
G Cd53 Cd53 molecule JBrowse link 2 209,489,279 209,537,098 RGD:1624291
G Flot2 flotillin 2 JBrowse link 10 65,304,901 65,329,332 RGD:1624291
RGD:1600115
G Klhl41 kelch-like family member 41 JBrowse link 3 55,910,177 55,923,303 RGD:1624291
RGD:13792537
RGD:1600115
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1624291
RGD:1600115
G Trip4 thyroid hormone receptor interactor 4 JBrowse link 8 71,369,121 71,533,281 RGD:1624291
RGD:1600115
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:1624291
RGD:1600115
regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
G Tbx2 T-box transcription factor 2 JBrowse link 10 73,278,932 73,290,764 RGD:1624291

Term paths to the root
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Term Annotations click to browse term
  biological_process 18008
    cellular process 16139
      cellular developmental process 4350
        cell differentiation 4137
          myoblast differentiation 99
            cardiac muscle cell myoblast differentiation + 11
            myoblast development + 2
            myoblast differentiation involved in skeletal muscle regeneration + 4
            myoblast fate commitment + 4
            negative regulation of myoblast differentiation + 29
            positive regulation of myoblast differentiation + 27
            regulation of myoblast differentiation + 61
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.