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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of B cell differentiation
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Accession:GO:0045578 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of B cell differentiation;   downregulation of B cell differentiation;   negative regulation of B lymphocyte differentiation
 narrow_synonym: inhibition of B cell differentiation
 related_synonym: negative regulation of B cell development


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negative regulation of B cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 Fms related receptor tyrosine kinase 3 ISO (MGI:MGI:3623701|PMID:16618805) RGD PMID:16618805 MGI:MGI:3623701 NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570
JBrowse link
G Hmgb3 high mobility group box 3 ISO (MGI:MGI:2670545|PMID:12714519) RGD PMID:12714519 MGI:MGI:2670545 NCBI chr17:36,690,190...36,694,329
Ensembl chr17:36,690,249...36,694,325
Ensembl chr14:36,690,249...36,694,325
JBrowse link
G Id2 inhibitor of DNA binding 2 ISO MGI:MGI:2384134 (MGI:MGI:3805135|PMID:18523151) RGD PMID:18523151 MGI:MGI:3805135 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 IEA
ISO
GO_REF:0000107
(MGI:MGI:3814493|PMID:18941195)
(PMID:18941195)
Ensembl
RGD
PMID:18941195 GO_REF:0000107, MGI:MGI:3814493 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    immune system process 2844
      leukocyte activation 1058
        lymphocyte activation 873
          lymphocyte differentiation 409
            B cell differentiation 148
              negative regulation of B cell differentiation 4
                negative regulation of B-1 B cell differentiation 0
                negative regulation of central B cell anergy 0
                negative regulation of central B cell deletion 0
                negative regulation of plasma cell differentiation 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            immune system development 1073
              hematopoietic or lymphoid organ development 1008
                hemopoiesis 956
                  leukocyte differentiation 597
                    lymphocyte differentiation 409
                      B cell differentiation 148
                        regulation of B cell differentiation 33
                          negative regulation of B cell differentiation 4
                            negative regulation of B-1 B cell differentiation 0
                            negative regulation of central B cell anergy 0
                            negative regulation of central B cell deletion 0
                            negative regulation of plasma cell differentiation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.