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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of B cell differentiation
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Accession:GO:0045578 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of B cell differentiation;   downregulation of B cell differentiation;   negative regulation of B lymphocyte differentiation
 narrow_synonym: inhibition of B cell differentiation
 related_synonym: negative regulation of B cell development


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negative regulation of B cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flt3 Fms related receptor tyrosine kinase 3 JBrowse link 12 9,360,439 9,437,004 RGD:1624291
G Hmgb3 high mobility group box 3 JBrowse link 17 36,690,190 36,694,329 RGD:1624291
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    immune system process 2692
      leukocyte activation 1008
        lymphocyte activation 828
          lymphocyte differentiation 392
            B cell differentiation 137
              negative regulation of B cell differentiation 4
                negative regulation of B-1 B cell differentiation 0
                negative regulation of central B cell anergy 0
                negative regulation of central B cell deletion 0
                negative regulation of plasma cell differentiation 0
Path 2
Term Annotations click to browse term
  biological_process 19576
    developmental process 6694
      anatomical structure development 6153
        multicellular organism development 5621
          system development 5156
            immune system development 1046
              hematopoietic or lymphoid organ development 982
                hemopoiesis 930
                  leukocyte differentiation 575
                    lymphocyte differentiation 392
                      B cell differentiation 137
                        regulation of B cell differentiation 31
                          negative regulation of B cell differentiation 4
                            negative regulation of B-1 B cell differentiation 0
                            negative regulation of central B cell anergy 0
                            negative regulation of central B cell deletion 0
                            negative regulation of plasma cell differentiation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.