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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of endothelial cell differentiation
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Accession:GO:0045602 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.
Synonyms:exact_synonym: down regulation of endothelial cell differentiation;   downregulation of endothelial cell differentiation
 narrow_synonym: inhibition of endothelial cell differentiation


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negative regulation of endothelial cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 ISO (MGI:MGI:4830635|PMID:20406889) RGD PMID:20406889 MGI:MGI:4830635 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein IMP RGD PMID:20830586 RGD:9686141 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Jag1 jagged canonical Notch ligand 1 IEA
ISO
GO_REF:0000107
(MGI:MGI:5661129|PMID:25535084)
Ensembl
RGD
PMID:25535084 GO_REF:0000107, MGI:MGI:5661129 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Notch4 notch receptor 4 ISO (MGI:MGI:1934537|PMID:11344305) RGD PMID:11344305 MGI:MGI:1934537 NCBI chr20:4,329,794...4,353,868
Ensembl chr20:4,329,811...4,353,785
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 IMP RGD PMID:17450384 RGD:2302022 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO MGI:MGI:2136645|MGI:MGI:3608931 (MGI:MGI:5618205|PMID:25186293) RGD PMID:25186293 MGI:MGI:5618205 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
G Xdh xanthine dehydrogenase IEA
ISO
GO_REF:0000107
(PMID:18386220)
Ensembl
RGD
PMID:18386220 GO_REF:0000107 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 ISO
IEA
(PMID:23765923)
GO_REF:0000107
RGD
Ensembl
PMID:23765923 GO_REF:0000107 NCBI chr17:54,656,627...54,714,920
Ensembl chr17:54,658,463...54,714,914
JBrowse link
negative regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxj2 forkhead box J2 ISO (PMID:24792364) RGD PMID:24792364 NCBI chr 4:155,653,446...155,679,815
Ensembl chr 4:155,653,718...155,679,793
JBrowse link
negative regulation of establishment of endothelial barrier term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G S1pr3 sphingosine-1-phosphate receptor 3 ISO (PMID:24851274) RGD PMID:24851274 NCBI chr17:13,799,383...13,812,877
Ensembl chr17:13,799,383...13,812,704
JBrowse link
G Vegfa vascular endothelial growth factor A ISO (PMID:20048167) RGD PMID:20048167 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    cellular process 18800
      negative regulation of cellular process 5156
        negative regulation of cell differentiation 735
          negative regulation of epithelial cell differentiation 50
            negative regulation of endothelial cell differentiation 11
              negative regulation of blood vessel endothelial cell differentiation + 1
              negative regulation of endothelial cell development + 2
Path 2
Term Annotations click to browse term
  biological_process 20028
    developmental process 6827
      anatomical structure development 6269
        tissue development 2099
          epithelium development 1263
            epithelial cell differentiation 711
              regulation of epithelial cell differentiation 160
                regulation of endothelial cell differentiation 43
                  negative regulation of endothelial cell differentiation 11
                    negative regulation of blood vessel endothelial cell differentiation + 1
                    negative regulation of endothelial cell development + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.