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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epidermal cell differentiation
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Accession:GO:0045605 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
Synonyms:exact_synonym: down regulation of epidermal cell differentiation;   downregulation of epidermal cell differentiation
 narrow_synonym: inhibition of epidermal cell differentiation
 related_synonym: negative regulation of hypodermal cell differentiation


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negative regulation of epidermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 ISO (MGI:MGI:3793982|PMID:17960184) UniProtKB PMID:17960184 MGI:MGI:3793982 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO (MGI:MGI:3846264|PMID:19303854) MGI PMID:19303854 MGI:MGI:3846264 NCBI chr 7:140,536,962...140,613,104
Ensembl chr 7:153,017,590...153,059,726
JBrowse link
G GDF3 growth differentiation factor 3 ISO (PMID:18823971) UniProtKB PMID:18823971 NCBI chr12:7,813,288...7,819,418
Ensembl chr12:7,972,907...7,979,815
JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 ISO (MGI:MGI:3621102|PMID:16495313) MGI PMID:16495313 MGI:MGI:3621102 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759
JBrowse link
G HES1 hes family bHLH transcription factor 1 ISO (MGI:MGI:1889857|PMID:11023859), (MGI:MGI:2136156|PMID:11425898)
(MGI:MGI:4949990|PMID:21300049)
MGI PMID:11023859, PMID:11425898, PMID:21300049 MGI:MGI:1889857, MGI:MGI:2136156, MGI:MGI:4949990 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257
JBrowse link
G HES5 hes family bHLH transcription factor 5 ISO (MGI:MGI:4949990|PMID:21300049)
(MGI:MGI:2136156|PMID:11425898)
MGI PMID:11425898, PMID:21300049 MGI:MGI:2136156, MGI:MGI:4949990 NCBI chr 1:1,261,260...1,263,128 JBrowse link
G NOTCH1 notch receptor 1 ISO (MGI:MGI:5617067|PMID:25535395) MGI PMID:25535395 MGI:MGI:5617067 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740
JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRHL2 grainyhead like transcription factor 2 ISO (PMID:23254293) UniProtKB PMID:23254293 NCBI chr 8:98,129,147...98,308,120
Ensembl chr 8:100,308,575...100,471,830
JBrowse link
G HOXA7 homeobox A7 ISO (PMID:11435435) MGI PMID:11435435 NCBI chr 7:27,799,317...27,802,492
Ensembl chr 7:27,396,898...27,402,142
JBrowse link
G MSX2 msh homeobox 2 ISO (MGI:MGI:4868690|PMID:19769717) MGI PMID:19769717 MGI:MGI:4868690 NCBI chr 5:170,063,137...170,070,226
Ensembl chr 5:176,967,902...176,976,609
JBrowse link
G OVOL2 ovo like zinc finger 2 ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chr20:17,983,277...18,019,441
Ensembl chr20:17,962,123...17,994,486
JBrowse link
G REG3G regenerating family member 3 gamma ISO (MGI:MGI:5488867|PMID:22727489) UniProtKB PMID:22727489 MGI:MGI:5488867 NCBI chr2A:79,116,083...79,118,886
Ensembl chr2A:80,680,615...80,683,748
JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 ISO (PMID:24440982) UniProtKB PMID:24440982 NCBI chr20:39,795,659...39,801,864
Ensembl chr20:40,888,560...40,891,853
JBrowse link
G TP63 tumor protein p63 ISO (MGI:MGI:5310685|PMID:22274697)
(MGI:MGI:3623698|PMID:16618808)
MGI PMID:16618808, PMID:22274697 MGI:MGI:3623698, MGI:MGI:5310685 NCBI chr 3:186,651,879...186,918,300
Ensembl chr 3:195,199,167...195,474,104
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12564
    negative regulation of biological process 4828
      negative regulation of developmental process 929
        negative regulation of epidermis development 13
          negative regulation of epidermal cell differentiation 13
            negative regulation of inner ear auditory receptor cell differentiation + 4
            negative regulation of keratinocyte differentiation 7
Path 2
Term Annotations click to browse term
  biological_process 12564
    developmental process 5839
      anatomical structure development 5452
        tissue development 1920
          epithelium development 1177
            epithelial cell differentiation 643
              epidermal cell differentiation 171
                regulation of epidermal cell differentiation 54
                  negative regulation of epidermal cell differentiation 13
                    negative regulation of inner ear auditory receptor cell differentiation + 4
                    negative regulation of keratinocyte differentiation 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.