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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epidermal cell differentiation
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Accession:GO:0045605 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
Synonyms:exact_synonym: down regulation of epidermal cell differentiation;   downregulation of epidermal cell differentiation
 narrow_synonym: inhibition of epidermal cell differentiation
 related_synonym: negative regulation of hypodermal cell differentiation


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negative regulation of epidermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 ISO (MGI:MGI:3793982|PMID:17960184) UniProtKB PMID:17960184 MGI:MGI:3793982 NCBI chrNW_004955411:3,478,943...3,486,541
Ensembl chrNW_004955411:3,478,033...3,486,604
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO (MGI:MGI:3846264|PMID:19303854) MGI PMID:19303854 MGI:MGI:3846264 NCBI chrNW_004955491:4,215,353...4,292,229
Ensembl chrNW_004955491:4,215,298...4,292,235
JBrowse link
G Gdf3 growth differentiation factor 3 ISO (PMID:18823971) UniProtKB PMID:18823971 NCBI chrNW_004955413:6,493,734...6,516,315 JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 ISO (MGI:MGI:3621102|PMID:16495313) MGI PMID:16495313 MGI:MGI:3621102 NCBI chrNW_004955411:3,478,943...3,486,541
Ensembl chrNW_004955411:3,478,033...3,486,604
JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO (MGI:MGI:1889857|PMID:11023859), (MGI:MGI:2136156|PMID:11425898)
(MGI:MGI:4949990|PMID:21300049)
MGI PMID:11023859, PMID:11425898, PMID:21300049 MGI:MGI:1889857, MGI:MGI:2136156, MGI:MGI:4949990 NCBI chrNW_004955420:14,565,921...14,568,447
Ensembl chrNW_004955420:14,564,283...14,568,447
JBrowse link
G Hes5 hes family bHLH transcription factor 5 ISO (MGI:MGI:4949990|PMID:21300049)
(MGI:MGI:2136156|PMID:11425898)
MGI PMID:11425898, PMID:21300049 MGI:MGI:2136156, MGI:MGI:4949990 NCBI chrNW_004955486:8,700,212...8,701,581
Ensembl chrNW_004955486:8,700,162...8,701,748
JBrowse link
G Notch1 notch receptor 1 ISO (MGI:MGI:5617067|PMID:25535395) MGI PMID:25535395 MGI:MGI:5617067 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259
JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grhl2 grainyhead like transcription factor 2 ISO (PMID:23254293) UniProtKB PMID:23254293 NCBI chrNW_004955417:26,401,337...26,533,297
Ensembl chrNW_004955417:26,401,363...26,533,297
JBrowse link
G Hoxa7 homeobox A7 ISO (PMID:11435435) MGI PMID:11435435 NCBI chrNW_004955410:28,848,029...28,851,069
Ensembl chrNW_004955410:28,847,893...28,851,062
JBrowse link
G Msx2 msh homeobox 2 ISO (MGI:MGI:4868690|PMID:19769717) MGI PMID:19769717 MGI:MGI:4868690 NCBI chrNW_004955408:27,323,405...27,329,484
Ensembl chrNW_004955408:27,323,360...27,329,755
JBrowse link
G Ovol2 ovo like zinc finger 2 ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chrNW_004955415:26,825,284...26,843,438
Ensembl chrNW_004955415:26,825,284...26,843,438
JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 ISO (PMID:24440982) UniProtKB PMID:24440982 NCBI chrNW_004955445:13,663,474...13,669,102
Ensembl chrNW_004955445:13,661,209...13,669,102
JBrowse link
G Tp63 tumor protein p63 ISO (MGI:MGI:5310685|PMID:22274697)
(MGI:MGI:3623698|PMID:16618808)
MGI PMID:16618808, PMID:22274697 MGI:MGI:3623698, MGI:MGI:5310685 NCBI chrNW_004955420:18,178,639...18,384,786
Ensembl chrNW_004955420:18,176,155...18,384,786
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11889
    negative regulation of biological process 4604
      negative regulation of developmental process 891
        negative regulation of epidermis development 12
          negative regulation of epidermal cell differentiation 12
            negative regulation of inner ear auditory receptor cell differentiation + 4
            negative regulation of keratinocyte differentiation 6
Path 2
Term Annotations click to browse term
  biological_process 11889
    developmental process 5616
      anatomical structure development 5254
        tissue development 1863
          epithelium development 1138
            epithelial cell differentiation 623
              epidermal cell differentiation 160
                regulation of epidermal cell differentiation 51
                  negative regulation of epidermal cell differentiation 12
                    negative regulation of inner ear auditory receptor cell differentiation + 4
                    negative regulation of keratinocyte differentiation 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.