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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epidermal cell differentiation
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Accession:GO:0045605 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
Synonyms:exact_synonym: down regulation of epidermal cell differentiation;   downregulation of epidermal cell differentiation
 narrow_synonym: inhibition of epidermal cell differentiation
 related_synonym: negative regulation of hypodermal cell differentiation


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negative regulation of epidermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 ISO (MGI:MGI:3793982|PMID:17960184) UniProtKB PMID:17960184 MGI:MGI:3793982 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit IEA Ensembl GO_REF:0000107 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838
JBrowse link
G GDF3 growth differentiation factor 3 IEA Ensembl GO_REF:0000107 NCBI chr27:37,125,845...37,129,567
Ensembl chr27:37,125,928...37,129,484
JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 IEA Ensembl GO_REF:0000107 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348
JBrowse link
G HES5 hes family bHLH transcription factor 5 IEA Ensembl GO_REF:0000107 NCBI chr 5:57,387,961...57,389,412
Ensembl chr 5:57,388,674...57,389,388
JBrowse link
G NOTCH1 notch receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRHL2 grainyhead like transcription factor 2 IEA Ensembl GO_REF:0000107 NCBI chr13:3,204,898...3,362,533
Ensembl chr13:3,204,925...3,362,096
JBrowse link
G HOXA7 homeobox A7 IEA Ensembl GO_REF:0000107 NCBI chr14:40,327,918...40,334,073
Ensembl chr14:40,329,127...40,330,842
JBrowse link
G MSX2 msh homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:38,002,724...38,007,407
Ensembl chr 4:38,002,428...38,007,407
JBrowse link
G OVOL2 ovo like zinc finger 2 ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chr24:5,020,608...5,050,487
Ensembl chr24:5,020,813...5,050,309
JBrowse link
G REG3A regenerating islet-derived 3 alpha ISO (MGI:MGI:5488867|PMID:22727489) UniProtKB PMID:22727489 MGI:MGI:5488867 NCBI chr17:44,859,106...44,864,793
Ensembl chr17:44,859,137...44,861,899
JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 IEA Ensembl GO_REF:0000107 NCBI chr24:31,217,190...31,222,852
Ensembl chr24:31,217,184...31,218,618
JBrowse link
G TP63 tumor protein p63 IEA Ensembl GO_REF:0000107 NCBI chr34:21,766,861...21,985,095
Ensembl chr34:21,766,496...21,983,046
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    negative regulation of biological process 5381
      negative regulation of developmental process 958
        negative regulation of epidermis development 12
          negative regulation of epidermal cell differentiation 12
            negative regulation of inner ear auditory receptor cell differentiation + 3
            negative regulation of keratinocyte differentiation 7
Path 2
Term Annotations click to browse term
  biological_process 16187
    developmental process 6309
      anatomical structure development 5857
        tissue development 2019
          epithelium development 1208
            epithelial cell differentiation 670
              epidermal cell differentiation 175
                regulation of epidermal cell differentiation 53
                  negative regulation of epidermal cell differentiation 12
                    negative regulation of inner ear auditory receptor cell differentiation + 3
                    negative regulation of keratinocyte differentiation 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.