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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epidermal cell differentiation
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Accession:GO:0045605 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
Synonyms:exact_synonym: down regulation of epidermal cell differentiation;   downregulation of epidermal cell differentiation
 narrow_synonym: inhibition of epidermal cell differentiation
 related_synonym: negative regulation of hypodermal cell differentiation


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negative regulation of epidermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 ISS UniProtKB GO_REF:0000024 NCBI chr 6:170,282,200...170,291,078
Ensembl chr 6:170,282,206...170,306,565
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit IEA Ensembl GO_REF:0000107 NCBI chr 7:148,807,374...148,884,344
Ensembl chr 7:148,807,383...148,884,321
JBrowse link
G GDF3 growth differentiation factor 3 IDA (PMID:18823971) UniProtKB PMID:18823971 NCBI chr12:7,689,784...7,695,775
Ensembl chr12:7,689,784...7,695,775
JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:170,282,200...170,291,078
Ensembl chr 6:170,282,206...170,306,565
JBrowse link
G HES1 hes family bHLH transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HES5 hes family bHLH transcription factor 5 IEA Ensembl GO_REF:0000107 NCBI chr 1:2,528,745...2,530,554
Ensembl chr 1:2,528,745...2,530,263
JBrowse link
G NOTCH1 notch receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRHL2 grainyhead like transcription factor 2 IDA (PMID:23254293) UniProtKB PMID:23254293 NCBI chr 8:101,492,439...101,678,104
Ensembl chr 8:101,492,439...101,669,726
JBrowse link
G HOXA7 homeobox A7 IDA (PMID:11435435) MGI PMID:11435435 NCBI chr 7:27,153,716...27,156,675
Ensembl chr 7:27,153,716...27,157,936
JBrowse link
G MSX2 msh homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:174,724,582...174,730,896
Ensembl chr 5:174,724,582...174,730,896
JBrowse link
G OVOL2 ovo like zinc finger 2 IMP (PMID:19700410) BHF-UCL PMID:19700410 NCBI chr20:18,024,152...18,059,188
Ensembl chr20:17,956,979...18,059,188
JBrowse link
G REG3A regenerating family member 3 alpha ISS UniProtKB GO_REF:0000024 NCBI chr 2:79,157,006...79,159,753
Ensembl chr 2:79,157,003...79,159,753
JBrowse link
G REG3G regenerating family member 3 gamma ISS UniProtKB GO_REF:0000024 NCBI chr 2:79,025,664...79,028,502
Ensembl chr 2:79,025,686...79,028,505
JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 IMP (PMID:24440982) UniProtKB PMID:24440982 NCBI chr20:43,457,893...43,464,243
Ensembl chr20:43,457,893...43,466,046
JBrowse link
G TP63 tumor protein p63 IEA Ensembl GO_REF:0000107 NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    negative regulation of biological process 6172
      negative regulation of developmental process 1060
        negative regulation of epidermis development 14
          negative regulation of epidermal cell differentiation 14
            negative regulation of inner ear auditory receptor cell differentiation + 4
            negative regulation of keratinocyte differentiation 8
Path 2
Term Annotations click to browse term
  biological_process 18670
    developmental process 7464
      anatomical structure development 6871
        tissue development 2422
          epithelium development 1532
            epithelial cell differentiation 913
              epidermal cell differentiation 395
                regulation of epidermal cell differentiation 65
                  negative regulation of epidermal cell differentiation 14
                    negative regulation of inner ear auditory receptor cell differentiation + 4
                    negative regulation of keratinocyte differentiation 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.