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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epidermal cell differentiation
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Accession:GO:0045605 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
Synonyms:exact_synonym: down regulation of epidermal cell differentiation;   downregulation of epidermal cell differentiation
 narrow_synonym: inhibition of epidermal cell differentiation
 related_synonym: negative regulation of hypodermal cell differentiation


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negative regulation of epidermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 ISO (MGI:MGI:3793982|PMID:17960184) UniProtKB PMID:17960184 MGI:MGI:3793982 NCBI chr 1:198,815...211,346
Ensembl chr 1:199,231...211,344
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit IEA Ensembl GO_REF:0000107 NCBI chr 9:109,384,976...109,450,943
Ensembl chr 9:109,384,995...109,450,941
JBrowse link
G GDF3 growth differentiation factor 3 IEA Ensembl GO_REF:0000107 NCBI chr 5:62,835,926...62,841,827
Ensembl chr 5:62,835,979...62,841,665
JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:198,815...211,346
Ensembl chr 1:199,231...211,344
JBrowse link
G HES1 hes family bHLH transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr13:131,135,970...131,137,865
Ensembl chr13:131,135,724...131,138,236
JBrowse link
G HES5 hes family bHLH transcription factor 5 IEA Ensembl GO_REF:0000107 NCBI chr 6:64,409,110...64,410,541
Ensembl chr 6:64,409,115...64,411,006
JBrowse link
G NOTCH1 notch receptor 1 IEA Ensembl GO_REF:0000107
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRHL2 grainyhead like transcription factor 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:35,368,788...35,565,394
Ensembl chr 4:35,371,136...35,564,919
JBrowse link
G HOXA7 homeobox A7 IEA Ensembl GO_REF:0000107 NCBI chr18:45,417,137...45,419,113
Ensembl chr18:45,417,203...45,419,136
JBrowse link
G MSX2 msh homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr16:49,765,587...49,771,745
Ensembl chr16:49,766,897...49,771,634
JBrowse link
G OVOL2 ovo like zinc finger 2 ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chr17:26,417,793...26,451,707
Ensembl chr17:26,417,795...26,451,928
JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 ISO (PMID:24440982) UniProtKB PMID:24440982 NCBI chr17:46,119,612...46,122,540
Ensembl chr17:46,119,409...46,173,944
JBrowse link
G TP63 tumor protein p63 IEA Ensembl GO_REF:0000107 NCBI chr13:127,115,990...127,347,082
Ensembl chr13:127,116,104...127,347,075
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16545
    negative regulation of biological process 5351
      negative regulation of developmental process 976
        negative regulation of epidermis development 12
          negative regulation of epidermal cell differentiation 12
            negative regulation of inner ear auditory receptor cell differentiation + 4
            negative regulation of keratinocyte differentiation 6
Path 2
Term Annotations click to browse term
  biological_process 16545
    developmental process 6302
      anatomical structure development 5842
        tissue development 2015
          epithelium development 1209
            epithelial cell differentiation 664
              epidermal cell differentiation 170
                regulation of epidermal cell differentiation 52
                  negative regulation of epidermal cell differentiation 12
                    negative regulation of inner ear auditory receptor cell differentiation + 4
                    negative regulation of keratinocyte differentiation 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.