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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epidermal cell differentiation
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Accession:GO:0045605 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
Synonyms:exact_synonym: down regulation of epidermal cell differentiation;   downregulation of epidermal cell differentiation
 narrow_synonym: inhibition of epidermal cell differentiation
 related_synonym: negative regulation of hypodermal cell differentiation


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negative regulation of epidermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 ISO
ISS
(MGI:MGI:3793982|PMID:17960184)
GO_REF:0000024
RGD
UniProt
PMID:17960184 GO_REF:0000024, MGI:MGI:3793982 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO MGI:MGI:2661097 (MGI:MGI:3846264|PMID:19303854) RGD PMID:19303854 MGI:MGI:3846264 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G Gdf3 growth differentiation factor 3 ISO (PMID:18823971) RGD PMID:18823971 NCBI chr 4:155,417,667...155,422,014
Ensembl chr 4:155,417,004...155,421,998
JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 ISO
IEA
MGI:MGI:1932522|MGI:MGI:3044907 (MGI:MGI:3621102|PMID:16495313)
GO_REF:0000107
RGD
Ensembl
PMID:16495313 GO_REF:0000107, MGI:MGI:3621102 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Hes1 hes family bHLH transcription factor 1 IEA
ISO
GO_REF:0000107
MGI:MGI:104876|MGI:MGI:1341800|MGI:MGI:2149672 (MGI:MGI:1889857|PMID:11023859), (MGI:MGI:2136156|PMID:11425898), (MGI:MGI:4949990|PMID:21300049)
Ensembl
RGD
PMID:11023859, PMID:11425898, PMID:21300049 GO_REF:0000107, MGI:MGI:1889857, MGI:MGI:2136156, MGI:MGI:4949990 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hes5 hes family bHLH transcription factor 5 ISO MGI:MGI:104853|MGI:MGI:1341800|MGI:MGI:2149674 (MGI:MGI:2136156|PMID:11425898), (MGI:MGI:4949990|PMID:21300049) RGD PMID:11425898, PMID:21300049 MGI:MGI:2136156, MGI:MGI:4949990 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Notch1 notch receptor 1 ISO MGI:MGI:3044585 (MGI:MGI:5617067|PMID:25535395) RGD PMID:25535395 MGI:MGI:5617067 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grhl2 grainyhead-like transcription factor 2 ISO (PMID:23254293) RGD PMID:23254293 NCBI chr 7:76,058,623...76,197,360
Ensembl chr 7:76,059,386...76,197,856
JBrowse link
G Hoxa7 homeobox A7 ISO (PMID:11435435) RGD PMID:11435435 NCBI chr 4:82,184,299...82,187,890
Ensembl chr 4:82,183,196...82,186,190
JBrowse link
G Msx2 msh homeobox 2 ISO
IEA
MGI:MGI:1926381 (MGI:MGI:4868690|PMID:19769717)
GO_REF:0000107
RGD
Ensembl
PMID:19769717 GO_REF:0000107, MGI:MGI:4868690 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Ovol2 ovo-like zinc finger 2 ISO (PMID:19700410) RGD PMID:19700410 NCBI chr 3:138,433,990...138,464,511
Ensembl chr 3:138,433,990...138,462,063
JBrowse link
G Reg3a regenerating islet-derived 3 alpha IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5488867|PMID:22727489)
Ensembl
UniProt
RGD
PMID:22727489 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5488867 NCBI chr 4:109,477,893...109,480,659
Ensembl chr 4:109,477,920...109,480,659
JBrowse link
G Reg3g regenerating family member 3 gamma ISO
ISS
(MGI:MGI:5488867|PMID:22727489)
GO_REF:0000024
RGD
UniProt
PMID:22727489 GO_REF:0000024, MGI:MGI:5488867 NCBI chr 4:109,529,679...109,532,234
Ensembl chr 4:109,529,679...109,532,234
JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 ISO
ISS
(PMID:24440982)
GO_REF:0000024
RGD
UniProt
PMID:24440982 GO_REF:0000024 NCBI chr 3:159,305,345...159,310,668
Ensembl chr 3:159,305,345...159,310,668
JBrowse link
G Tp63 tumor protein p63 ISO MGI:MGI:5140823|MGI:MGI:97363 (MGI:MGI:3623698|PMID:16618808), (MGI:MGI:5310685|PMID:22274697) RGD PMID:16618808, PMID:22274697 MGI:MGI:3623698, MGI:MGI:5310685 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    negative regulation of biological process 5686
      negative regulation of developmental process 1014
        negative regulation of epidermis development 14
          negative regulation of epidermal cell differentiation 14
            negative regulation of inner ear auditory receptor cell differentiation + 4
            negative regulation of keratinocyte differentiation 8
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        tissue development 2099
          epithelium development 1263
            epithelial cell differentiation 711
              epidermal cell differentiation 203
                regulation of epidermal cell differentiation 55
                  negative regulation of epidermal cell differentiation 14
                    negative regulation of inner ear auditory receptor cell differentiation + 4
                    negative regulation of keratinocyte differentiation 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.