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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epidermal cell differentiation
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Accession:GO:0045605 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
Synonyms:exact_synonym: down regulation of epidermal cell differentiation;   downregulation of epidermal cell differentiation
 narrow_synonym: inhibition of epidermal cell differentiation
 related_synonym: negative regulation of hypodermal cell differentiation


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negative regulation of epidermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 ISO (MGI:MGI:3793982|PMID:17960184) UniProtKB PMID:17960184 MGI:MGI:3793982 NCBI chrNW_004937098:212,704...220,589 JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO (MGI:MGI:3846264|PMID:19303854) MGI PMID:19303854 MGI:MGI:3846264 NCBI chrNW_004936527:5,024,077...5,069,152 JBrowse link
G Gdf3 growth differentiation factor 3 ISO (PMID:18823971) UniProtKB PMID:18823971 NCBI chrNW_004937847:8,179...16,783 JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 ISO (MGI:MGI:3621102|PMID:16495313) MGI PMID:16495313 MGI:MGI:3621102 NCBI chrNW_004937098:212,704...220,589 JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO (MGI:MGI:4949990|PMID:21300049)
(MGI:MGI:1889857|PMID:11023859), (MGI:MGI:2136156|PMID:11425898)
MGI PMID:11023859, PMID:11425898, PMID:21300049 MGI:MGI:1889857, MGI:MGI:2136156, MGI:MGI:4949990 NCBI chrNW_004936711:640,002...642,580 JBrowse link
G Hes5 hes family bHLH transcription factor 5 ISO (MGI:MGI:2136156|PMID:11425898)
(MGI:MGI:4949990|PMID:21300049)
MGI PMID:11425898, PMID:21300049 MGI:MGI:2136156, MGI:MGI:4949990 NCBI chrNW_004936737:1,045,496...1,047,865 JBrowse link
G Notch1 notch receptor 1 ISO (MGI:MGI:5617067|PMID:25535395) MGI PMID:25535395 MGI:MGI:5617067 NCBI chrNW_004936669:1,292,016...1,334,061 JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grhl2 grainyhead like transcription factor 2 ISO (PMID:23254293) UniProtKB PMID:23254293 NCBI chrNW_004936470:41,856,683...41,961,666 JBrowse link
G Hoxa7 homeobox A7 ISO (PMID:11435435) MGI PMID:11435435 NCBI chrNW_004936478:3,782,476...3,784,361 JBrowse link
G Msx2 msh homeobox 2 ISO (MGI:MGI:4868690|PMID:19769717) MGI PMID:19769717 MGI:MGI:4868690 NCBI chrNW_004936609:1,216,436...1,221,528 JBrowse link
G Ovol2 ovo like zinc finger 2 ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chrNW_004936485:2,096,495...2,128,002 JBrowse link
G Reg3g regenerating family member 3 gamma ISO (MGI:MGI:5488867|PMID:22727489) UniProtKB PMID:22727489 MGI:MGI:5488867 NCBI chrNW_004936556:4,896,141...4,898,240 JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 ISO (PMID:24440982) UniProtKB PMID:24440982 NCBI chrNW_004936530:3,086,944...3,092,780 JBrowse link
G Tp63 tumor protein p63 ISO (MGI:MGI:3623698|PMID:16618808)
(MGI:MGI:5310685|PMID:22274697)
MGI PMID:16618808, PMID:22274697 MGI:MGI:3623698, MGI:MGI:5310685 NCBI chrNW_004936578:492,267...705,282 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11998
    negative regulation of biological process 4639
      negative regulation of developmental process 902
        negative regulation of epidermis development 13
          negative regulation of epidermal cell differentiation 13
            negative regulation of inner ear auditory receptor cell differentiation + 4
            negative regulation of keratinocyte differentiation 7
Path 2
Term Annotations click to browse term
  biological_process 11998
    developmental process 5648
      anatomical structure development 5286
        tissue development 1870
          epithelium development 1139
            epithelial cell differentiation 624
              epidermal cell differentiation 164
                regulation of epidermal cell differentiation 53
                  negative regulation of epidermal cell differentiation 13
                    negative regulation of inner ear auditory receptor cell differentiation + 4
                    negative regulation of keratinocyte differentiation 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.