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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of inner ear auditory receptor cell differentiation
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Accession:GO:0045608 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation.
Synonyms:exact_synonym: down regulation of auditory receptor cell differentiation;   downregulation of auditory receptor cell differentiation;   negative regulation of auditory hair cell differentiation
 narrow_synonym: inhibition of auditory receptor cell differentiation
 related_synonym: negative regulation of auditory receptor cell differentiation


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negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 ISO
IEA
MGI:MGI:1932522|MGI:MGI:3044907 (MGI:MGI:3621102|PMID:16495313)
GO_REF:0000107
RGD
Ensembl
PMID:16495313 GO_REF:0000107, MGI:MGI:3621102 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Hes1 hes family bHLH transcription factor 1 IEA
ISO
GO_REF:0000107
MGI:MGI:104876|MGI:MGI:1341800|MGI:MGI:2149672 (MGI:MGI:1889857|PMID:11023859), (MGI:MGI:2136156|PMID:11425898), (MGI:MGI:4949990|PMID:21300049)
Ensembl
RGD
PMID:11023859, PMID:11425898, PMID:21300049 GO_REF:0000107, MGI:MGI:1889857, MGI:MGI:2136156, MGI:MGI:4949990 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hes5 hes family bHLH transcription factor 5 ISO MGI:MGI:104853|MGI:MGI:1341800|MGI:MGI:2149674 (MGI:MGI:2136156|PMID:11425898), (MGI:MGI:4949990|PMID:21300049) RGD PMID:11425898, PMID:21300049 MGI:MGI:2136156, MGI:MGI:4949990 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Notch1 notch receptor 1 ISO MGI:MGI:3044585 (MGI:MGI:5617067|PMID:25535395) RGD PMID:25535395 MGI:MGI:5617067 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure morphogenesis 2877
        regulation of anatomical structure morphogenesis 994
          inhibition of neuroepithelial cell differentiation 5
            negative regulation of inner ear auditory receptor cell differentiation 4
              negative regulation of auditory receptor cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            nervous system development 2722
              neurogenesis 1938
                generation of neurons 1781
                  neuron differentiation 1617
                    mechanoreceptor differentiation 93
                      inner ear receptor cell differentiation 85
                        inner ear auditory receptor cell differentiation 54
                          regulation of inner ear auditory receptor cell differentiation 10
                            negative regulation of inner ear auditory receptor cell differentiation 4
                              negative regulation of auditory receptor cell fate specification 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.