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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of keratinocyte differentiation
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Accession:GO:0045616 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of keratinocyte differentiation.


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regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd109 CD109 molecule ISO (MGI:MGI:5441431|PMID:22490868) MGI PMID:22490868 MGI:MGI:5441431 NCBI chrNW_004955488:9,281,407...9,378,354 JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 ISO (MGI:MGI:3629275|PMID:16648858) UniProtKB PMID:16648858 MGI:MGI:3629275 NCBI chrNW_004955486:4,941,143...4,955,693 JBrowse link
G Grhl1 grainyhead like transcription factor 1 ISO (MGI:MGI:5585711|PMID:24586629) MGI PMID:24586629 MGI:MGI:5585711 NCBI chrNW_004955487:5,407,187...5,432,828 JBrowse link
G Krt36 keratin 36 ISO (MGI:MGI:50776|PMID:1385239) UniProtKB PMID:1385239 MGI:MGI:50776 NCBI chrNW_004955451:15,828,596...15,837,892 JBrowse link
G Krt84 keratin 84 ISO (MGI:MGI:50776|PMID:1385239) UniProtKB PMID:1385239 MGI:MGI:50776 NCBI chrNW_004955547:2,729,046...2,737,142 JBrowse link
G Rock1 Rho associated coiled-coil containing protein kinase 1 ISO (PMID:19997641) UniProtKB PMID:19997641 NCBI chrNW_004955402:9,752,101...9,864,317 JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 ISO (PMID:19997641) UniProtKB PMID:19997641 NCBI chrNW_004955487:5,856,190...5,972,408 JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 ISO (MGI:MGI:5503267|PMID:23637227) UniProt PMID:23637227 MGI:MGI:5503267 NCBI chrNW_004955466:6,075,507...6,103,739 JBrowse link
G Zfp36 ZFP36 ring finger protein ISO (PMID:27182009) UniProtKB PMID:27182009 NCBI chrNW_004955468:152,744...155,140 JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 ISO (PMID:27182009) UniProtKB PMID:27182009 NCBI chrNW_004955466:1,541,367...1,546,617 JBrowse link
negative regulation of cornification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdsn corneodesmosin ISO (PMID:26014679) CAFA PMID:26014679 NCBI chrNW_004955583:959,544...968,632 JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grhl2 grainyhead like transcription factor 2 ISO (PMID:23254293) UniProtKB PMID:23254293 NCBI chrNW_004955417:26,401,337...26,533,297 JBrowse link
G Hoxa7 homeobox A7 ISO (PMID:11435435) MGI PMID:11435435 NCBI chrNW_004955410:28,848,029...28,851,069 JBrowse link
G Msx2 msh homeobox 2 ISO (MGI:MGI:4868690|PMID:19769717) MGI PMID:19769717 MGI:MGI:4868690 NCBI chrNW_004955408:27,323,405...27,329,484 JBrowse link
G Ovol2 ovo like zinc finger 2 ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chrNW_004955415:26,825,284...26,843,438 JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 ISO (PMID:24440982) UniProtKB PMID:24440982 NCBI chrNW_004955445:13,663,474...13,669,102 JBrowse link
G Tp63 tumor protein p63 ISO (MGI:MGI:5310685|PMID:22274697)
(MGI:MGI:3623698|PMID:16618808)
MGI PMID:16618808, PMID:22274697 MGI:MGI:3623698, MGI:MGI:5310685 NCBI chrNW_004955420:18,178,639...18,384,786 JBrowse link
positive regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15b arachidonate 15-lipoxygenase type B ISO (MGI:MGI:3784332|PMID:10965849) UniProtKB PMID:10965849 MGI:MGI:3784332 NCBI chrNW_004955467:8,896,740...8,906,032 JBrowse link
G Etv4 ETS variant transcription factor 4 ISO (PMID:31552090) UniProt PMID:31552090 NCBI chrNW_004955451:16,965,404...16,976,503 JBrowse link
G LOC102008188 core histone macro-H2A.1 ISO (PMID:23595991) UniProtKB PMID:23595991 NCBI chrNW_004955408:30,497,531...30,550,095 JBrowse link
G LOC102011841 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial ISO (PMID:12496369) BHF-UCL PMID:12496369 NCBI chrNW_004955458:5,472,404...5,477,001 JBrowse link
G LOC102017503 core histone macro-H2A.2 ISO (PMID:23595991) UniProtKB PMID:23595991 NCBI chrNW_004955437:21,126,581...21,186,308 JBrowse link
G Med1 mediator complex subunit 1 ISO (PMID:17082781) UniProtKB PMID:17082781 NCBI chrNW_004955451:14,204,326...14,237,809 JBrowse link
G Ncoa3 nuclear receptor coactivator 3 ISO (PMID:17082781), (PMID:17223341) UniProtKB PMID:17082781, PMID:17223341 NCBI chrNW_004955445:10,020,916...10,085,318 JBrowse link
G Notch1 notch receptor 1 ISO (MGI:MGI:3689772|PMID:17079689)
(MGI:MGI:3623698|PMID:16618808)
MGI PMID:16618808, PMID:17079689 MGI:MGI:3623698, MGI:MGI:3689772 NCBI chrNW_004955513:4,225,939...4,264,875 JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 ISO (MGI:MGI:5754878|PMID:26765568) UniProtKB PMID:26765568 MGI:MGI:5754878 NCBI chrNW_004955414:19,252,191...19,327,504 JBrowse link
G Ovol2 ovo like zinc finger 2 ISO (MGI:MGI:5584327|PMID:24735878) MGI PMID:24735878 MGI:MGI:5584327 NCBI chrNW_004955415:26,825,284...26,843,438 JBrowse link
G Prkch protein kinase C eta ISO (MGI:MGI:5306545|PMID:21346190) UniProtKB PMID:21346190 MGI:MGI:5306545 NCBI chrNW_004955466:8,178,323...8,393,446 JBrowse link
G Trim16 tripartite motif containing 16 ISO (PMID:11919186) UniProtKB PMID:11919186 NCBI chrNW_004955467:2,059,793...2,084,221 JBrowse link
G Vdr vitamin D receptor ISO (PMID:17082781) UniProtKB PMID:17082781 NCBI chrNW_004955500:6,745,725...6,798,052 JBrowse link
G Zbed2 zinc finger BED-type containing 2 ISO (PMID:31552090) HGNC PMID:31552090 NCBI chrNW_004955427:12,007,646...12,009,431 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11857
    regulation of biological process 8250
      regulation of developmental process 2531
        regulation of epidermis development 76
          regulation of epidermal cell differentiation 52
            regulation of keratinocyte differentiation 30
              negative regulation of keratinocyte differentiation + 7
              positive regulation of keratinocyte differentiation + 14
              regulation of cornification + 1
Path 2
Term Annotations click to browse term
  biological_process 11857
    developmental process 5599
      anatomical structure development 5237
        tissue development 1857
          epithelium development 1133
            epithelial cell differentiation 620
              epidermal cell differentiation 160
                keratinocyte differentiation 89
                  regulation of keratinocyte differentiation 30
                    negative regulation of keratinocyte differentiation + 7
                    positive regulation of keratinocyte differentiation + 14
                    regulation of cornification + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.