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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of keratinocyte differentiation
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Accession:GO:0045616 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of keratinocyte differentiation.


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regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd109 CD109 molecule ISO (MGI:MGI:5441431|PMID:22490868) MGI PMID:22490868 MGI:MGI:5441431 NCBI chrNW_004936859:467,958...595,337 JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 ISO (MGI:MGI:3629275|PMID:16648858) UniProtKB PMID:16648858 MGI:MGI:3629275 NCBI chrNW_004936623:2,457,709...2,462,956 JBrowse link
G Grhl1 grainyhead like transcription factor 1 ISO (MGI:MGI:5585711|PMID:24586629) MGI PMID:24586629 MGI:MGI:5585711 NCBI chrNW_004936532:6,199,525...6,247,282 JBrowse link
G Krt36 keratin 36 ISO (MGI:MGI:50776|PMID:1385239) UniProtKB PMID:1385239 MGI:MGI:50776 NCBI chrNW_004936490:16,394,193...16,408,224 JBrowse link
G Krt84 keratin 84 ISO (MGI:MGI:50776|PMID:1385239) UniProtKB PMID:1385239 MGI:MGI:50776 NCBI chrNW_004936512:9,784,467...9,792,289 JBrowse link
G Rock1 Rho associated coiled-coil containing protein kinase 1 ISO (PMID:19997641) UniProtKB PMID:19997641 NCBI chrNW_004936550:730,462...874,601 JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 ISO (PMID:19997641) UniProtKB PMID:19997641 NCBI chrNW_004936532:7,142,580...7,284,722 JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 ISO (MGI:MGI:5503267|PMID:23637227) UniProt PMID:23637227 MGI:MGI:5503267 NCBI chrNW_004936495:7,500,991...7,528,520 JBrowse link
G Zfp36 ZFP36 ring finger protein ISO (PMID:27182009) UniProtKB PMID:27182009 NCBI chrNW_004936661:2,251,148...2,253,527 JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 ISO (PMID:27182009) UniProtKB PMID:27182009 NCBI chrNW_004936495:12,045,679...12,050,737 JBrowse link
negative regulation of cornification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdsn corneodesmosin ISO (PMID:26014679) CAFA PMID:26014679 NCBI chrNW_004936837:787,035...791,388 JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grhl2 grainyhead like transcription factor 2 ISO (PMID:23254293) UniProtKB PMID:23254293 NCBI chrNW_004936470:41,856,683...41,961,666 JBrowse link
G Hoxa7 homeobox A7 ISO (PMID:11435435) MGI PMID:11435435 NCBI chrNW_004936478:3,782,476...3,784,361 JBrowse link
G Msx2 msh homeobox 2 ISO (MGI:MGI:4868690|PMID:19769717) MGI PMID:19769717 MGI:MGI:4868690 NCBI chrNW_004936609:1,216,436...1,221,528 JBrowse link
G Ovol2 ovo like zinc finger 2 ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chrNW_004936485:2,096,495...2,128,002 JBrowse link
G Reg3g regenerating family member 3 gamma ISO (MGI:MGI:5488867|PMID:22727489) UniProtKB PMID:22727489 MGI:MGI:5488867 NCBI chrNW_004936556:4,896,141...4,898,240 JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 ISO (PMID:24440982) UniProtKB PMID:24440982 NCBI chrNW_004936530:3,086,944...3,092,780 JBrowse link
G Tp63 tumor protein p63 ISO (MGI:MGI:3623698|PMID:16618808)
(MGI:MGI:5310685|PMID:22274697)
MGI PMID:16618808, PMID:22274697 MGI:MGI:3623698, MGI:MGI:5310685 NCBI chrNW_004936578:492,267...705,282 JBrowse link
positive regulation of keratinocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15b arachidonate 15-lipoxygenase type B ISO (MGI:MGI:3784332|PMID:10965849) UniProtKB PMID:10965849 MGI:MGI:3784332 NCBI chrNW_004936595:1,279,944...1,288,321 JBrowse link
G Etv4 ETS variant transcription factor 4 ISO (PMID:31552090) UniProt PMID:31552090 NCBI chrNW_004936541:120,533...138,463 JBrowse link
G LOC101956559 core histone macro-H2A.2 ISO (PMID:23595991) UniProtKB PMID:23595991 NCBI chrNW_004936521:8,474,408...8,509,269 JBrowse link
G LOC101971629 core histone macro-H2A.1 ISO (PMID:23595991) UniProtKB PMID:23595991 NCBI chrNW_004936597:2,496,489...2,556,352 JBrowse link
G LOC101978323 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial ISO (PMID:12496369) BHF-UCL PMID:12496369 NCBI chrNW_004936646:1,899,686...1,904,104 JBrowse link
G Med1 mediator complex subunit 1 ISO (PMID:17082781) UniProtKB PMID:17082781 NCBI chrNW_004936490:14,625,201...14,663,184 JBrowse link
G Ncoa3 nuclear receptor coactivator 3 ISO (PMID:17082781), (PMID:17223341) UniProtKB PMID:17082781, PMID:17223341 NCBI chrNW_004936514:5,900,135...5,967,862 JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO (PMID:16862176) HGNC PMID:16862176 NCBI chrNW_004936490:10,634,788...10,640,182 JBrowse link
G Notch1 notch receptor 1 ISO (MGI:MGI:3689772|PMID:17079689)
(MGI:MGI:3623698|PMID:16618808)
MGI PMID:16618808, PMID:17079689 MGI:MGI:3623698, MGI:MGI:3689772 NCBI chrNW_004936669:1,292,016...1,334,061 JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 ISO (MGI:MGI:5754878|PMID:26765568) UniProtKB PMID:26765568 MGI:MGI:5754878 NCBI chrNW_004936498:1,358,598...1,438,041 JBrowse link
G Ovol2 ovo like zinc finger 2 ISO (MGI:MGI:5584327|PMID:24735878) MGI PMID:24735878 MGI:MGI:5584327 NCBI chrNW_004936485:2,096,495...2,128,002 JBrowse link
G Prkch protein kinase C eta ISO (MGI:MGI:5306545|PMID:21346190) UniProtKB PMID:21346190 MGI:MGI:5306545 NCBI chrNW_004936495:5,426,243...5,638,250 JBrowse link
G Trim16 tripartite motif containing 16 ISO (PMID:11919186) UniProtKB PMID:11919186 NCBI chrNW_004936724:2,101,942...2,122,747 JBrowse link
G Vdr vitamin D receptor ISO (PMID:17082781) UniProtKB PMID:17082781 NCBI chrNW_004936512:5,741,836...5,800,999 JBrowse link
G Zbed2 zinc finger BED-type containing 2 ISO (PMID:31552090) HGNC PMID:31552090 NCBI chrNW_004936834:473,265...474,584 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    regulation of biological process 8316
      regulation of developmental process 2544
        regulation of epidermis development 78
          regulation of epidermal cell differentiation 54
            regulation of keratinocyte differentiation 32
              negative regulation of keratinocyte differentiation + 8
              positive regulation of keratinocyte differentiation + 15
              regulation of cornification + 1
Path 2
Term Annotations click to browse term
  biological_process 11962
    developmental process 5628
      anatomical structure development 5266
        tissue development 1864
          epithelium development 1134
            epithelial cell differentiation 621
              epidermal cell differentiation 164
                keratinocyte differentiation 91
                  regulation of keratinocyte differentiation 32
                    negative regulation of keratinocyte differentiation + 8
                    positive regulation of keratinocyte differentiation + 15
                    regulation of cornification + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.