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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of T-helper cell differentiation
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Accession:GO:0045624 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: up regulation of T-helper cell differentiation;   upregulation of T-helper cell differentiation
 narrow_synonym: activation of T-helper cell differentiation;   stimulation of T-helper cell differentiation
 related_synonym: positive regulation of T-helper cell development


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positive regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myb MYB proto-oncogene, transcription factor JBrowse link NW_004955439 1,523,516 1,560,185 RGD:9068941
G Shb SH2 domain containing adaptor protein B JBrowse link NW_004955419 28,423,354 28,555,948 RGD:9068941
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link NW_004955512 5,686,508 5,703,645 RGD:9068941
G Ccl19 C-C motif chemokine ligand 19 JBrowse link NW_004955472 1,444,598 1,446,488 RGD:9068941
G Hlx H2.0 like homeobox JBrowse link NW_004955520 2,937,131 2,941,170 RGD:9068941
G Ripk2 receptor interacting serine/threonine kinase 2 JBrowse link NW_004955417 6,669,675 6,698,142 RGD:9068941
G Socs5 suppressor of cytokine signaling 5 JBrowse link NW_004955441 13,593,342 13,657,389 RGD:9068941
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Malt1 MALT1 paracaspase JBrowse link NW_004955402 42,919,480 42,968,873 RGD:9068941
G Nfkbid NFKB inhibitor delta JBrowse link NW_004955468 2,680,934 2,688,797 RGD:9068941
G Nfkbiz NFKB inhibitor zeta JBrowse link NW_004955427 3,350,174 3,358,609 RGD:9068941
G Nlrp3 NLR family pyrin domain containing 3 JBrowse link NW_004955581 597,952 616,903 RGD:9068941
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il23a interleukin 23 subunit alpha JBrowse link NW_004955458 3,946,964 3,949,180 RGD:9068941
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il18 interleukin 18 JBrowse link NW_004955412 13,807,361 13,826,007 RGD:9068941
G Il4r interleukin 4 receptor JBrowse link NW_004955493 5,546,340 5,580,745 RGD:9068941
G Il6 interleukin 6 JBrowse link NW_004955410 25,079,835 25,084,390 RGD:9068941
G Nlrp3 NLR family pyrin domain containing 3 JBrowse link NW_004955581 597,952 616,903 RGD:9068941
G Prkcz protein kinase C zeta JBrowse link NW_004955486 8,947,579 9,021,702 RGD:9068941
G Rara retinoic acid receptor alpha JBrowse link NW_004955451 14,876,663 14,917,134 RGD:9068941
G Tnfsf4 TNF superfamily member 4 JBrowse link NW_004955406 13,477,077 13,493,309 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11826
    immune system process 1887
      immune effector process 594
        positive regulation of immune effector process 220
          positive regulation of T-helper cell differentiation 18
            positive regulation of T-helper 1 cell differentiation 5
            positive regulation of T-helper 17 cell differentiation + 5
            positive regulation of T-helper 2 cell differentiation 7
Path 2
Term Annotations click to browse term
  biological_process 11826
    developmental process 5545
      anatomical structure development 5187
        multicellular organism development 4753
          system development 4496
            immune system development 908
              hematopoietic or lymphoid organ development 852
                hemopoiesis 806
                  leukocyte differentiation 505
                    lymphocyte differentiation 342
                      T cell differentiation 255
                        T cell differentiation involved in immune response 68
                          alpha-beta T cell differentiation involved in immune response 61
                            CD4-positive, alpha-beta T cell differentiation involved in immune response 60
                              T-helper cell differentiation 58
                                regulation of T-helper cell differentiation 34
                                  positive regulation of T-helper cell differentiation 18
                                    positive regulation of T-helper 1 cell differentiation 5
                                    positive regulation of T-helper 17 cell differentiation + 5
                                    positive regulation of T-helper 2 cell differentiation 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.