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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of T-helper cell differentiation
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Accession:GO:0045624 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: up regulation of T-helper cell differentiation;   upregulation of T-helper cell differentiation
 narrow_synonym: activation of T-helper cell differentiation;   stimulation of T-helper cell differentiation
 related_synonym: positive regulation of T-helper cell development


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positive regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MYB MYB proto-oncogene, transcription factor JBrowse link 1 27,908,309 27,991,984 RGD:9068941
G SHB SH2 domain containing adaptor protein B JBrowse link 11 54,189,580 54,329,004 RGD:13508589
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA1 annexin A1 JBrowse link 1 84,744,159 84,763,011 RGD:13508589
G CCL19 C-C motif chemokine ligand 19 JBrowse link 11 51,357,706 51,359,207 RGD:9068941
G HLX H2.0 like homeobox JBrowse link 38 15,538,744 15,543,686 RGD:13508589
G RIPK2 receptor interacting serine/threonine kinase 2 JBrowse link 29 35,283,209 35,311,608 RGD:13508589
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 10 48,916,446 48,977,183 RGD:13508589
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MALT1 MALT1 paracaspase JBrowse link 1 17,351,458 17,412,591 RGD:13508589
G MIR326 microRNA mir-326 JBrowse link 21 23,240,463 23,240,553 RGD:9068941
G NFKBID NFKB inhibitor delta JBrowse link 1 116,763,371 116,770,683 RGD:13508589
G NFKBIZ NFKB inhibitor zeta JBrowse link 33 8,147,160 8,154,401 RGD:9068941
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 8 251,776 313,290 RGD:13508589
G TYROBP transmembrane immune signaling adaptor TYROBP JBrowse link 1 116,757,271 116,760,453 RGD:13508589
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL23A interleukin 23 subunit alpha JBrowse link 10 635,384 640,715 RGD:13508589
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL18 interleukin 18 JBrowse link 5 20,972,742 20,995,327 RGD:13508589
G IL4R interleukin 4 receptor JBrowse link 6 19,254,183 19,280,973 RGD:9068941
G IL6 interleukin 6 JBrowse link 14 36,474,268 36,478,519 RGD:9068941
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 8 251,776 313,290 RGD:13508589
G PRKCZ protein kinase C zeta JBrowse link 5 57,012,020 57,113,346 RGD:13508589
G RARA retinoic acid receptor alpha JBrowse link 9 22,254,803 22,298,614 RGD:13508589
G TNFSF4 TNF superfamily member 4 JBrowse link 7 25,883,297 25,909,608 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16042
    immune system process 2246
      immune effector process 691
        positive regulation of immune effector process 241
          positive regulation of T-helper cell differentiation 20
            positive regulation of T-helper 1 cell differentiation 5
            positive regulation of T-helper 17 cell differentiation + 7
            positive regulation of T-helper 2 cell differentiation 7
Path 2
Term Annotations click to browse term
  biological_process 16042
    developmental process 6212
      anatomical structure development 5762
        multicellular organism development 5250
          system development 4915
            immune system development 1000
              hematopoietic or lymphoid organ development 938
                hemopoiesis 891
                  leukocyte differentiation 558
                    lymphocyte differentiation 378
                      T cell differentiation 277
                        T cell differentiation involved in immune response 75
                          alpha-beta T cell differentiation involved in immune response 67
                            CD4-positive, alpha-beta T cell differentiation involved in immune response 66
                              T-helper cell differentiation 64
                                regulation of T-helper cell differentiation 38
                                  positive regulation of T-helper cell differentiation 20
                                    positive regulation of T-helper 1 cell differentiation 5
                                    positive regulation of T-helper 17 cell differentiation + 7
                                    positive regulation of T-helper 2 cell differentiation 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.