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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of T-helper 1 cell differentiation
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Accession:GO:0045626 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of T-helper 1 cell differentiation;   downregulation of T-helper 1 cell differentiation
 narrow_synonym: inhibition of T-helper 1 cell differentiation
 related_synonym: negative regulation of T-helper 1 cell development


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negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:1624291
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:1600115
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    immune system process 2631
      immune effector process 849
        negative regulation of immune effector process 140
          negative regulation of T-helper cell differentiation 19
            negative regulation of T-helper 1 cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 19439
    developmental process 6673
      anatomical structure development 6138
        multicellular organism development 5605
          system development 5126
            immune system development 1040
              hematopoietic or lymphoid organ development 976
                hemopoiesis 924
                  leukocyte differentiation 571
                    lymphocyte differentiation 389
                      T cell differentiation 276
                        T cell differentiation involved in immune response 72
                          alpha-beta T cell differentiation involved in immune response 65
                            CD4-positive, alpha-beta T cell differentiation involved in immune response 64
                              T-helper cell differentiation 62
                                regulation of T-helper cell differentiation 38
                                  negative regulation of T-helper cell differentiation 19
                                    negative regulation of T-helper 1 cell differentiation 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.