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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of T-helper 2 cell differentiation
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Accession:GO:0045629 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of T-helper 2 cell differentiation;   downregulation of T-helper 2 cell differentiation
 narrow_synonym: inhibition of T-helper 2 cell differentiation
 related_synonym: negative regulation of T-helper 2 cell development


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negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:1624291
RGD:13792537
RGD:1600115
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Hlx H2.0-like homeobox JBrowse link 13 102,637,967 102,643,376 RGD:1624291
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
G Zfp35 zinc finger protein 35 JBrowse link 18 15,883,182 15,898,803 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19575
    immune system process 2692
      immune response 1625
        type 2 immune response 39
          negative regulation of type 2 immune response 14
            negative regulation of T-helper 2 cell differentiation 5
Path 2
Term Annotations click to browse term
  biological_process 19575
    developmental process 6692
      anatomical structure development 6151
        multicellular organism development 5619
          system development 5155
            immune system development 1046
              hematopoietic or lymphoid organ development 982
                hemopoiesis 930
                  leukocyte differentiation 575
                    lymphocyte differentiation 392
                      T cell differentiation 279
                        T cell differentiation involved in immune response 72
                          alpha-beta T cell differentiation involved in immune response 65
                            CD4-positive, alpha-beta T cell differentiation involved in immune response 64
                              T-helper cell differentiation 62
                                regulation of T-helper cell differentiation 38
                                  negative regulation of T-helper cell differentiation 19
                                    negative regulation of T-helper 2 cell differentiation 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.