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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of osteoblast differentiation
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Accession:GO:0045669 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
Synonyms:exact_synonym: up regulation of osteoblast differentiation;   upregulation of osteoblast differentiation
 narrow_synonym: activation of osteoblast differentiation;   stimulation of osteoblast differentiation


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positive regulation of osteoblast differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 ISO
IEA
(PMID:18436533)
GO_REF:0000107
RGD
Ensembl
PMID:18436533 GO_REF:0000107 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Acvr2a activin A receptor type 2A ISO
IEA
(PMID:18436533)
GO_REF:0000107
RGD
Ensembl
PMID:18436533 GO_REF:0000107 NCBI chr 3:32,947,901...33,034,598
Ensembl chr 3:32,947,378...33,034,282
JBrowse link
G Acvr2b activin A receptor type 2B ISO
IEA
(PMID:18436533)
GO_REF:0000107
RGD
Ensembl
PMID:18436533 GO_REF:0000107 NCBI chr 8:128,087,308...128,126,776
Ensembl chr 8:128,087,345...128,118,746
JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 IEA
ISO
ISS
GO_REF:0000107
(MGI:5575464|PMID:22467241)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:22467241 GO_REF:0000024, GO_REF:0000107, MGI:5575464 NCBI chr  X:156,407,973...156,415,053
Ensembl chr  X:156,407,937...156,415,145
JBrowse link
G Atraid all-trans retinoic acid-induced differentiation factor ISO (PMID:21723284) RGD PMID:21723284 NCBI chr 6:26,680,628...26,685,185
Ensembl chr 6:26,680,598...26,685,235
JBrowse link
G Bmp2 bone morphogenetic protein 2 ISS
ISO
GO_REF:0000024
(MGI:3050916|PMID:15175325), (MGI:3587162|PMID:16099986), (MGI:5009350|PMID:20675382)
(PMID:15254224), (PMID:16433617), (PMID:18436533), (PMID:20576608)
UniProt
RGD
PMID:15175325, PMID:15254224, PMID:16099986, PMID:16433617, PMID:18436533, PMID:20576608, PMID:20675382 GO_REF:0000024, MGI:3050916, MGI:3587162, MGI:5009350 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp4 bone morphogenetic protein 4 IMP
ISO
ISS
IEA
IDA
(PMID:14749725), (PMID:18436533)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:14749725, PMID:18436533, PMID:17112416, PMID:16245174 GO_REF:0000024, GO_REF:0000107, RGD:1643600, RGD:2289011 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp6 bone morphogenetic protein 6 IMP
ISO
(PMID:18436533) RGD PMID:18436533, PMID:9202223 RGD:2289027 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A ISO (PMID:18436533) RGD PMID:18436533 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 2:247,392,195...247,662,026
Ensembl chr 2:247,403,920...247,446,882
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO (PMID:18436533) RGD PMID:18436533 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Ccn1 cellular communication network factor 1 ISO
IEA
(PMID:20675382)
GO_REF:0000107
RGD
Ensembl
PMID:20675382 GO_REF:0000107 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccn4 cellular communication network factor 4 IEA
ISO
GO_REF:0000107
(PMID:20684029)
Ensembl
RGD
PMID:20684029 GO_REF:0000107 NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772
JBrowse link
G Cd276 Cd276 molecule ISO MGI:3033707 (MGI:3052626|PMID:15317945) RGD PMID:15317945 MGI:3052626 NCBI chr 8:63,312,060...63,350,411
Ensembl chr 8:63,318,019...63,350,269
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha IEA
ISO
GO_REF:0000107
(MGI:3050916|PMID:15175325)
Ensembl
RGD
PMID:15175325 GO_REF:0000107, MGI:3050916 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO (MGI:3050916|PMID:15175325) RGD PMID:15175325 MGI:3050916 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta ISO (MGI:3050916|PMID:15175325) RGD PMID:15175325 MGI:3050916 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Clic1 chloride intracellular channel 1 ISO (MGI:4410403|PMID:19703605) RGD PMID:19703605 MGI:4410403 NCBI chr20:5,040,314...5,049,166
Ensembl chr20:5,040,337...5,049,166
JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 ISO MGI:3830252 (MGI:3829514|PMID:18779865) RGD PMID:18779865 MGI:3829514 NCBI chr 7:77,966,722...77,977,004
Ensembl chr 7:77,966,722...77,977,004
JBrowse link
G Ctnnb1 catenin beta 1 IEA
ISO
GO_REF:0000107
MGI:2148591|MGI:2148594|MGI:2450929 (MGI:3578464|PMID:15866163)
Ensembl
RGD
PMID:15866163 GO_REF:0000107, MGI:3578464 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 ISO (PMID:18977368) RGD PMID:18977368 NCBI chr 5:166,464,170...166,513,030
Ensembl chr 5:166,464,252...166,513,027
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO (PMID:20564243) RGD PMID:20564243 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Dlx5 distal-less homeobox 5 IMP RGD PMID:12815054 RGD:1298882 NCBI chr 4:32,387,741...32,392,085
Ensembl chr 4:32,387,741...32,392,007
JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 IEA
ISO
GO_REF:0000107
(MGI:6450489|PMID:25498833)
Ensembl
RGD
PMID:25498833 GO_REF:0000107, MGI:6450489 NCBI chr 2:251,912,432...251,970,699
Ensembl chr 2:251,912,368...251,970,768
JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase ISO (MGI:5427766|PMID:22615579) RGD PMID:22615579 MGI:5427766 NCBI chr12:17,913,771...17,972,733
Ensembl chr12:17,913,767...17,972,737
JBrowse link
G Fbn2 fibrillin 2 ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr18:53,068,495...53,272,254
Ensembl chr18:53,068,495...53,181,503
JBrowse link
G Fbxo5 F-box protein 5 ISO (PMID:29850565) RGD PMID:29850565 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Fermt2 fermitin family member 2 ISO (PMID:29496737)
(MGI:6149626|PMID:29496737)
RGD PMID:29496737 MGI:6149626 NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408
JBrowse link
G Ffar4 free fatty acid receptor 4 ISS
ISO
GO_REF:0000024
(MGI:6220333|PMID:26365922)
UniProt
RGD
PMID:26365922 GO_REF:0000024, MGI:6220333 NCBI chr 1:256,786,124...256,804,156
Ensembl chr 1:256,786,124...256,804,156
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO MGI:95729 (MGI:4821204|PMID:20570969) RGD PMID:20570969 MGI:4821204 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Gdf10 growth differentiation factor 10 IDA RGD PMID:12559390 RGD:2316372 NCBI chr16:10,250,508...10,262,383
Ensembl chr16:10,250,404...10,263,150
JBrowse link
G Gdpd2 glycerophosphodiester phosphodiesterase domain containing 2 ISO (MGI:2679742|PMID:12933806) RGD PMID:12933806 MGI:2679742 NCBI chr  X:70,563,381...70,572,295
Ensembl chr  X:70,563,570...70,572,295
JBrowse link
G Gli3 GLI family zinc finger 3 ISO MGI:1856276|MGI:95516 (MGI:4821204|PMID:20570969) RGD PMID:20570969 MGI:4821204 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
JBrowse link
G Gnas GNAS complex locus ISO MGI:3043361 (MGI:3619837|PMID:15797856) RGD PMID:15797856 MGI:3619837 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISO MGI:1321394|MGI:99829 (MGI:3836510|PMID:18986983) RGD PMID:18986983 MGI:3836510 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Igf1 insulin-like growth factor 1 IDA
IEA
ISO
GO_REF:0000107
(PMID:16433617)
Ensembl
RGD
PMID:16433617, PMID:16897348 GO_REF:0000107, RGD:1598452 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il6 interleukin 6 ISO (PMID:30545407) RGD PMID:30545407 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6st interleukin 6 signal transducer ISO
IEA
(PMID:12372336)
GO_REF:0000107
RGD
Ensembl
PMID:12372336 GO_REF:0000107 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Ilk integrin-linked kinase ISO (MGI:5009350|PMID:20675382) RGD PMID:20675382 MGI:5009350 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Jag1 jagged canonical Notch ligand 1 IEA
ISO
GO_REF:0000107
(MGI:5522615|PMID:23980096)
Ensembl
RGD
PMID:23980096 GO_REF:0000107, MGI:5522615 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit ISO MGI:1316736 (MGI:3573815|PMID:15563473) RGD PMID:15563473 MGI:3573815 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Lmna lamin A/C IMP RGD PMID:22119912 RGD:10003161 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Lrp3 LDL receptor related protein 3 ISO (PMID:28340487) RGD PMID:28340487 NCBI chr 1:91,447,308...91,462,603
Ensembl chr 1:91,448,361...91,462,603
JBrowse link
G Lrp5 LDL receptor related protein 5 ISO (MGI:6162346|PMID:26891291) RGD PMID:26891291 MGI:6162346 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094
JBrowse link
G Ltf lactotransferrin ISO (PMID:15166119) RGD PMID:15166119 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Mef2c myocyte enhancer factor 2C IEA
ISO
ISS
GO_REF:0000107
(MGI:5285459|PMID:21652706)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21652706 GO_REF:0000024, GO_REF:0000107, MGI:5285459 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Men1 menin 1 ISO MGI:88177 (MGI:3056877|PMID:15150273) RGD PMID:15150273 MGI:3056877 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Mir210 microRNA 210 ISO (MGI:3851892|PMID:19520079) RGD PMID:19520079 MGI:3851892 NCBI chr 1:214,208,355...214,208,464 JBrowse link
G Mnda myeloid cell nuclear differentiation antigen ISO MGI:88177 (MGI:3530710|PMID:15557274) RGD PMID:15557274 MGI:3530710 NCBI chr13:92,073,664...92,091,335
Ensembl chr13:92,073,668...92,089,980
JBrowse link
G Msx2 msh homeobox 2 IEA
ISO
GO_REF:0000107
(MGI:3050916|PMID:15175325)
Ensembl
RGD
PMID:15175325 GO_REF:0000107, MGI:3050916 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Nell1 neural EGFL like 1 ISO
ISS
(PMID:21723284)
GO_REF:0000024
RGD
UniProt
PMID:21723284 GO_REF:0000024 NCBI chr 1:105,348,577...106,218,970
Ensembl chr 1:105,349,069...106,218,958
JBrowse link
G Npnt nephronectin ISO (MGI:4414689|PMID:19944102), (MGI:5285024|PMID:21689636) RGD PMID:19944102, PMID:21689636 MGI:4414689, MGI:5285024 NCBI chr 2:238,001,767...238,068,886
Ensembl chr 2:238,002,990...238,068,694
JBrowse link
G Nppc natriuretic peptide C IDA RGD PMID:17562543 RGD:1642298 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Pdlim7 PDZ and LIM domain 7 IDA RGD PMID:9832452 RGD:632731 NCBI chr17:9,653,510...9,668,715
Ensembl chr17:9,653,561...9,668,712
JBrowse link
G Prkd1 protein kinase D1 ISS
ISO
GO_REF:0000024
(MGI:5306577|PMID:19029091)
UniProt
RGD
PMID:19029091 GO_REF:0000024, MGI:5306577 NCBI chr 6:71,035,017...71,349,531
Ensembl chr 6:71,035,332...71,349,249
JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:14751573 RGD:10043372 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Runx2 RUNX family transcription factor 2 IEA
ISO
ISS
GO_REF:0000107
MGI:1316736|MGI:1341800 (MGI:3050916|PMID:15175325), (MGI:3056877|PMID:15150273), (MGI:3836510|PMID:18986983)
GO_REF:0000024
(PMID:28703881)
Ensembl
RGD
UniProt
PMID:15150273, PMID:15175325, PMID:18986983, PMID:28703881 GO_REF:0000024, GO_REF:0000107, MGI:3050916, MGI:3056877, MGI:3836510 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 ISO MGI:5698367|MGI:96533 (MGI:5698232|PMID:25639508) RGD PMID:25639508 MGI:5698232 NCBI chr 1:174,428,056...174,495,356
Ensembl chr 1:174,428,699...174,495,258
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 ISO MGI:98956 (MGI:3772759|PMID:18166153) RGD PMID:18166153 MGI:3772759 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Smad1 SMAD family member 1 IEA
ISO
GO_REF:0000107
MGI:1316736 (MGI:3056877|PMID:15150273)
Ensembl
RGD
PMID:15150273 GO_REF:0000107, MGI:3056877 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684
JBrowse link
G Smad5 SMAD family member 5 ISO MGI:1316736 (MGI:3056877|PMID:15150273) RGD PMID:15150273 MGI:3056877 NCBI chr17:8,307,448...8,336,996
Ensembl chr17:8,311,796...8,331,032
JBrowse link
G Sox11 SRY-box transcription factor 11 ISO
ISS
(PMID:20626275)
GO_REF:0000024
RGD
UniProt
PMID:20626275 GO_REF:0000024 NCBI chr 6:46,629,967...46,631,988
Ensembl chr 6:46,629,974...46,631,983
JBrowse link
G Suco SUN domain containing ossification factor IEA
ISO
ISS
GO_REF:0000107
(MGI:4452525|PMID:20440000)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:20440000 GO_REF:0000024, GO_REF:0000107, MGI:4452525 NCBI chr13:79,736,485...79,801,133
Ensembl chr13:79,736,482...79,801,561
JBrowse link
G Tmem119 transmembrane protein 119 ISO
IBA
(PMID:20025746)
(MGI:4418582|PMID:20025746), (MGI:5543589|PMID:22416756), (MGI:6294241|PMID:22579779)
PMID:21873635
RGD PMID:20025746, PMID:22416756, PMID:22579779, PMID:21873635 MGI:4418582, MGI:5543589, MGI:6294241, RGD:13792537 NCBI chr12:48,598,498...48,605,704
Ensembl chr12:48,598,647...48,605,704
JBrowse link
G Tp63 tumor protein p63 ISO (PMID:22521434) RGD PMID:22521434 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Vegfa vascular endothelial growth factor A ISO MGI:1931048 (MGI:5461755|PMID:22886301) RGD PMID:22886301 MGI:5461755 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wnt10b Wnt family member 10B ISO (MGI:3574150|PMID:15728361), (MGI:4358631|PMID:19723499) RGD PMID:15728361, PMID:19723499 MGI:3574150, MGI:4358631 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
G Wnt4 Wnt family member 4 ISO
IEA
(PMID:17720811)
GO_REF:0000107
RGD
Ensembl
PMID:17720811 GO_REF:0000107 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
G Wnt7b Wnt family member 7B ISO (MGI:3511731|PMID:15576404) RGD PMID:15576404 MGI:3511731 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 ISO UniProtKB:Q96AC1 (PMID:29496737) RGD PMID:29496737 NCBI chr 2:147,577,149...147,693,033
Ensembl chr 2:147,577,089...147,693,082
JBrowse link
G Yap1 Yes1 associated transcriptional regulator ISO (PMID:29496737) RGD PMID:29496737 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 ISO
ISS
(PMID:21174497)
GO_REF:0000024
RGD
UniProt
PMID:21174497 GO_REF:0000024 NCBI chr 3:156,759,820...156,868,173
Ensembl chr 3:156,764,751...156,777,999
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    positive regulation of biological process 6648
      positive regulation of cellular process 6145
        positive regulation of cell differentiation 961
          positive regulation of osteoblast differentiation 73
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      cellular developmental process 4457
        cell differentiation 4362
          regulation of cell differentiation 1684
            regulation of osteoblast differentiation 150
              positive regulation of osteoblast differentiation 73
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.