ONTOLOGY REPORT - ANNOTATIONS


Term:low-density lipoprotein particle receptor biosynthetic process
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Accession:GO:0045713 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors, cell surface proteins that mediate the endocytosis of low-density lipoprotein particles by cells.
Synonyms:exact_synonym: LDLr biosynthesis;   LDLr biosynthetic process;   low-density lipoprotein receptor anabolism;   low-density lipoprotein receptor biosynthesis;   low-density lipoprotein receptor biosynthetic process;   low-density lipoprotein receptor formation;   low-density lipoprotein receptor synthesis


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low-density lipoprotein particle receptor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:1624291
RGD:1600115
negative regulation of low-density lipoprotein particle receptor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:1624291
RGD:1600115
G Itgav integrin subunit alpha V JBrowse link 3 71,113,269 71,205,958 RGD:1624291
RGD:1600115
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:1624291
positive regulation of low-density lipoprotein particle receptor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnpy2 canopy FGF signaling regulator 2 JBrowse link 7 2,737,674 2,744,321 RGD:1624291
RGD:1600115
G Hnrnpk heterogeneous nuclear ribonucleoprotein K JBrowse link 17 6,664,730 6,676,753 RGD:1624291
RGD:1600115
regulation of low-density lipoprotein particle receptor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1624291
RGD:1600115
G Sec24a SEC24 homolog A, COPII coat complex component JBrowse link 10 37,138,539 37,215,899 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17941
    metabolic process 10685
      primary metabolic process 9624
        protein metabolic process 5532
          low-density lipoprotein particle receptor biosynthetic process 8
            negative regulation of low-density lipoprotein particle receptor biosynthetic process 3
            positive regulation of low-density lipoprotein particle receptor biosynthetic process 2
            regulation of low-density lipoprotein particle receptor biosynthetic process + 7
Path 2
Term Annotations click to browse term
  biological_process 17941
    metabolic process 10685
      organic substance metabolic process 10138
        macromolecule metabolic process 8690
          cellular macromolecule metabolic process 7490
            receptor metabolic process 209
              low-density lipoprotein receptor particle metabolic process 12
                low-density lipoprotein particle receptor biosynthetic process 8
                  negative regulation of low-density lipoprotein particle receptor biosynthetic process 3
                  positive regulation of low-density lipoprotein particle receptor biosynthetic process 2
                  regulation of low-density lipoprotein particle receptor biosynthetic process + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.