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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of fatty acid biosynthetic process
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Accession:GO:0045717 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
Synonyms:exact_synonym: down regulation of fatty acid biosynthetic process;   downregulation of fatty acid biosynthetic process;   negative regulation of fatty acid anabolism;   negative regulation of fatty acid biosynthesis;   negative regulation of fatty acid formation;   negative regulation of fatty acid synthesis
 narrow_synonym: inhibition of fatty acid biosynthetic process


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negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain ISO (MGI:MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:MGI:3526480 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain ISO
IEA
(MGI:MGI:3526480|PMID:15639194)
GO_REF:0000107
RGD
Ensembl
PMID:15639194 GO_REF:0000107, MGI:MGI:3526480 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Apoc1 apolipoprotein C1 ISO (PMID:15576844) RGD PMID:15576844 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoc3 apolipoprotein C3 IEA
ISO
GO_REF:0000107
(PMID:11060345), (PMID:18635818)
Ensembl
RGD
PMID:11060345, PMID:18635818 GO_REF:0000107 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Brca1 BRCA1, DNA repair associated IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:16326698)
Ensembl
UniProt
RGD
PMID:16326698, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 IMP PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Erlin1 ER lipid raft associated 1 ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:263,810,439...263,845,762
Ensembl chr 1:263,810,439...263,845,762
JBrowse link
G Erlin2 ER lipid raft associated 2 ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:69,179,005...69,195,452
Ensembl chr16:69,179,588...69,195,097
JBrowse link
G Insig1 insulin induced gene 1 ISO MGI:MGI:1920249 (MGI:MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:MGI:3603108 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insig2 insulin induced gene 2 ISO MGI:MGI:1916289 (MGI:MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:MGI:3603108 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Trib3 tribbles pseudokinase 3 ISO (MGI:MGI:3630230|PMID:16794074) RGD PMID:16794074 MGI:MGI:3630230 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Wdtc1 WD and tetratricopeptide repeats 1 ISO
IBA
(MGI:MGI:3770497|PMID:17767906)
PMID:21873635
RGD PMID:17767906, PMID:21873635 MGI:MGI:3770497, RGD:13792537 NCBI chr 5:151,487,572...151,536,829
Ensembl chr 5:151,487,577...151,536,518
JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pibf1 progesterone immunomodulatory binding factor 1 ISO (PMID:3863495) RGD PMID:3863495 NCBI chr15:83,494,110...83,663,202
Ensembl chr15:83,495,377...83,663,143
JBrowse link
G Sirt1 sirtuin 1 ISO (MGI:MGI:5306564|PMID:20042607) RGD PMID:20042607 MGI:MGI:5306564 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      biosynthetic process 6217
        negative regulation of biosynthetic process 1702
          negative regulation of cellular biosynthetic process 1661
            negative regulation of fatty acid biosynthetic process 15
              negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA 0
              negative regulation of butyryl-CoA catabolic process to butyrate 0
              negative regulation of methyl-branched fatty acid biosynthetic process 0
              negative regulation of prostaglandin biosynthetic process 2
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      cellular metabolic process 11065
        organic acid metabolic process 1090
          oxoacid metabolic process 1061
            carboxylic acid metabolic process 1005
              monocarboxylic acid metabolic process 665
                fatty acid metabolic process 423
                  fatty acid biosynthetic process 156
                    regulation of fatty acid biosynthetic process 46
                      negative regulation of fatty acid biosynthetic process 15
                        negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA 0
                        negative regulation of butyryl-CoA catabolic process to butyrate 0
                        negative regulation of methyl-branched fatty acid biosynthetic process 0
                        negative regulation of prostaglandin biosynthetic process 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.