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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA repair
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Accession:GO:0045738 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair.
Synonyms:exact_synonym: down regulation of DNA repair;   downregulation of DNA repair
 narrow_synonym: inhibition of DNA repair


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negative regulation of DNA repair term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rps3 ribosomal protein S3 JBrowse link 1 164,435,868 164,441,167 RGD:1624291
negative regulation of double-strand break repair term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 JBrowse link 1 222,451,674 222,459,952 RGD:1624291
RGD:13792537
RGD:1600115
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 JBrowse link 6 127,282,445 127,301,086 RGD:13792537
G Rnf169 ring finger protein 169 JBrowse link 1 164,917,069 164,978,061 RGD:1624291
G Trip12 thyroid hormone receptor interactor 12 JBrowse link 9 92,305,059 92,435,388 RGD:1600115
RGD:1624291
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 JBrowse link 7
7
76,789,110
76,839,661
76,835,517
76,907,441
RGD:1600115
RGD:1624291
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cgas cyclic GMP-AMP synthase JBrowse link 8 85,789,515 85,804,008 RGD:1624291
RGD:13792537
G Fancb FA complementation group B JBrowse link X 31,124,018 31,140,790 RGD:1624291
RGD:13792537
G Fbh1 F-box DNA helicase 1 JBrowse link 17 70,399,093 70,437,151 RGD:1624291
G Helb DNA helicase B JBrowse link 7 64,860,641 64,888,146 RGD:1624291
RGD:13792537
G Klhl15 kelch-like family member 15 JBrowse link X 63,342,277 63,390,915 RGD:1624291
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link 5 164,943,183 164,956,255 RGD:1624291
G Parpbp PARP1 binding protein JBrowse link 7 28,654,707 28,724,412 RGD:1624291
RGD:1600115
G Polq DNA polymerase theta JBrowse link 11 66,585,860 66,695,369 RGD:1624291
G Radx RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 110,670,037 110,782,420 RGD:1624291
RGD:1600115
G Recql5 RecQ like helicase 5 JBrowse link 10 104,443,735 104,482,889 RGD:1624291
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
G Rmi2 RecQ mediated genome instability 2 JBrowse link 10 4,904,458 4,910,339 RGD:13792537
G Shld1 shieldin complex subunit 1 JBrowse link 3 125,318,682 125,396,705 RGD:1624291
RGD:13792537
G Shld2 shieldin complex subunit 2 JBrowse link 16 10,570,307 10,661,528 RGD:1624291
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 9 119,675,750 119,818,620 RGD:1624291
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link 3 113,160,030 113,259,701 RGD:1624291
G Ubqln4 ubiquilin 4 JBrowse link 2 187,915,701 187,931,035 RGD:1624291
negative regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aunip aurora kinase A and ninein interacting protein JBrowse link 5 152,721,799 152,734,577 RGD:1624291
RGD:1600115
G Cyren cell cycle regulator of NHEJ JBrowse link 4 62,391,770 62,397,162 RGD:1624291
RGD:1600115
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:1624291
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1624291
RGD:1600115
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:1624291
G Nudt16l1 nudix hydrolase 16 like 1 JBrowse link 10 10,829,866 10,831,782 RGD:1624291
negative regulation of double-strand break repair via single-strand annealing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ogg1 8-oxoguanine DNA glycosylase JBrowse link 4 145,282,828 145,289,367 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    cellular process 18452
      negative regulation of cellular process 5071
        negative regulation of response to DNA damage stimulus 77
          negative regulation of DNA repair 31
            negative regulation of base-excision repair 0
            negative regulation of double-strand break repair + 30
            negative regulation of error-prone translesion synthesis 0
            negative regulation of mismatch repair 0
            negative regulation of single strand break repair + 0
Path 2
Term Annotations click to browse term
  biological_process 19678
    metabolic process 11954
      cellular metabolic process 10782
        cellular aromatic compound metabolic process 5534
          nucleobase-containing compound metabolic process 5311
            nucleic acid metabolic process 4822
              DNA metabolic process 906
                DNA repair 475
                  regulation of DNA repair 128
                    negative regulation of DNA repair 31
                      negative regulation of base-excision repair 0
                      negative regulation of double-strand break repair + 30
                      negative regulation of error-prone translesion synthesis 0
                      negative regulation of mismatch repair 0
                      negative regulation of single strand break repair + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.