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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of G protein-coupled receptor signaling pathway
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Accession:GO:0045745 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.
Synonyms:exact_synonym: positive regulation of G protein coupled receptor protein signaling pathway;   positive regulation of G protein coupled receptor protein signalling pathway;   positive regulation of GPCR protein signaling pathway;   positive regulation of GPCR protein signalling pathway;   up regulation of G-protein coupled receptor protein signaling pathway;   upregulation of G-protein coupled receptor protein signaling pathway
 narrow_synonym: activation of G-protein coupled receptor protein signaling pathway;   stimulation of G-protein coupled receptor protein signaling pathway


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positive regulation of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein ISO (PMID:11316806) RGD PMID:11316806 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G C3 complement C3 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:15833747)
Ensembl
UniProt
RGD
PMID:15833747 GO_REF:0000024, GO_REF:0000107 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Drd2 dopamine receptor D2 IMP RGD PMID:18809670 RGD:2311559 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Ece1 endothelin converting enzyme 1 IMP RGD PMID:15733912 RGD:1581735 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Fgf8 fibroblast growth factor 8 ISO (MGI:MGI:3847828|PMID:19307307) RGD PMID:19307307 MGI:MGI:3847828 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 IDA
ISO
PMID:23994616
(MGI:MGI:6355742|PMID:23994616)
RGD PMID:23994616, PMID:23994616 MGI:MGI:6355742, RGD:14697711 NCBI chr10:70,639,429...70,646,402
Ensembl chr10:70,639,862...70,646,495
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:15539556)
Ensembl
UniProt
RGD
PMID:15539556 GO_REF:0000024, GO_REF:0000107 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Klk14 kallikrein related-peptidase 14 ISO (PMID:16885167) RGD PMID:16885167 NCBI chr 1:99,616,153...99,621,425
Ensembl chr 1:99,616,447...99,621,037
JBrowse link
G Klk5 kallikrein related-peptidase 5 ISO (PMID:16885167) RGD PMID:16885167 NCBI chr 1:99,781,291...99,793,745
Ensembl chr 1:99,781,237...99,786,330
JBrowse link
G Klk6 kallikrein related-peptidase 6 ISO (PMID:16885167) RGD PMID:16885167 NCBI chr 1:99,762,195...99,769,486
Ensembl chr 1:99,762,253...99,769,488
JBrowse link
G LOC108348322 GAS2-like protein 2 IDA PMID:23994616 UniProt PMID:23994616 RGD:14697711
G Myh9 myosin, heavy chain 9 IMP RGD PMID:20068007 RGD:6902910 NCBI chr 7:118,740,005...118,792,507
Ensembl chr 7:118,741,110...118,792,625
JBrowse link
G Pde6g phosphodiesterase 6G ISO
IBA
(MGI:MGI:2156093|PMID:11502744)
PMID:21873635
RGD PMID:11502744, PMID:21873635 MGI:MGI:2156093, RGD:13792537 NCBI chr10:109,620,499...109,625,214
Ensembl chr10:109,620,980...109,622,745
JBrowse link
G Pde6h phosphodiesterase 6H ISO
IBA
(MGI:MGI:2156093|PMID:11502744)
PMID:21873635
RGD PMID:11502744, PMID:21873635 MGI:MGI:2156093, RGD:13792537 NCBI chr 4:170,947,723...170,963,046
Ensembl chr 4:170,958,196...170,963,046
JBrowse link
G Phb prohibitin ISO (PMID:24732013) RGD PMID:24732013 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO (MGI:MGI:2670839|PMID:12878180) RGD PMID:12878180 MGI:MGI:2670839 NCBI chr 1:226,976,455...226,995,641
Ensembl chr 1:226,993,250...226,994,849
JBrowse link
G Slc39a14 solute carrier family 39 member 14 ISO (MGI:MGI:4950776|PMID:21445361) RGD PMID:21445361 MGI:MGI:4950776 NCBI chr15:51,982,872...52,029,841
Ensembl chr15:51,982,982...52,029,816
JBrowse link
G Tmod2 tropomodulin 2 ISO MGI:MGI:2664500 (MGI:MGI:2663390|PMID:12799133) RGD PMID:12799133 MGI:MGI:2663390 NCBI chr 8:82,505,947...82,547,450
Ensembl chr 8:82,506,934...82,533,689
JBrowse link
positive regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 IEA
ISO
GO_REF:0000107
(PMID:18940592), (PMID:22389722)
Ensembl
RGD
PMID:18940592, PMID:22389722 GO_REF:0000107 NCBI chr 8:112,838,574...112,884,062
Ensembl chr 8:112,834,707...112,884,077
JBrowse link
G Cntn2 contactin 2 ISO
IEA
MGI:MGI:2181052 (MGI:MGI:1930847|PMID:11178983)
GO_REF:0000107
RGD
Ensembl
PMID:11178983 GO_REF:0000107, MGI:MGI:1930847 NCBI chr13:49,280,913...49,314,061
Ensembl chr13:49,285,310...49,313,940
JBrowse link
G Necab2 N-terminal EF-hand calcium binding protein 2 ISO (PMID:17689978) RGD PMID:17689978 NCBI chr19:52,086,325...52,112,633
Ensembl chr19:52,086,325...52,112,629
JBrowse link
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3a glycogen synthase kinase 3 alpha ISO (MGI:MGI:4829580|PMID:20516643) RGD PMID:20516643 MGI:MGI:4829580 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos1 nitric oxide synthase 1 IEA
ISO
GO_REF:0000107
(MGI:MGI:3771112|PMID:17242280)
Ensembl
RGD
PMID:17242280 GO_REF:0000107, MGI:MGI:3771112 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18202135 RGD:5129138 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO (MGI:MGI:4829580|PMID:20516643) RGD PMID:20516643 MGI:MGI:4829580 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Mrap melanocortin 2 receptor accessory protein ISO (PMID:19329486) RGD PMID:19329486 NCBI chr11:30,904,733...30,915,225
Ensembl chr11:30,904,733...30,915,225
JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 ISO (PMID:19329486) RGD PMID:19329486 NCBI chr 8:94,801,336...94,858,192
Ensembl chr 8:94,801,336...94,857,443
JBrowse link
positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt5 protein arginine methyltransferase 5 ISO UniProtKB:P14416 (PMID:26554819) RGD PMID:26554819 NCBI chr15:33,156,508...33,165,893
Ensembl chr15:33,156,492...33,165,895
JBrowse link
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 IMP RGD PMID:17157995 RGD:1625132 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chga chromogranin A IDA RGD PMID:11257446 RGD:6907050 NCBI chr 6:126,434,226...126,445,569
Ensembl chr 6:126,434,226...126,445,568
JBrowse link
G F2 coagulation factor II ISO
IEA
(PMID:20164183)
GO_REF:0000107
RGD
Ensembl
PMID:20164183 GO_REF:0000107 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Gpr27 G protein-coupled receptor 27 ISO (MGI:MGI:5311513|PMID:22253604) RGD PMID:22253604 MGI:MGI:5311513 NCBI chr 4:132,137,793...132,138,926
Ensembl chr 4:132,137,793...132,138,926
JBrowse link
G Grp gastrin releasing peptide ISO
ISS
(MGI:MGI:5704231|PMID:26658875)
GO_REF:0000024
RGD
UniProt
PMID:26658875 GO_REF:0000024, MGI:MGI:5704231 NCBI chr18:61,563,458...61,576,818
Ensembl chr18:61,563,053...61,576,818
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    cellular process 18800
      signal transduction 7011
        G protein-coupled receptor signaling pathway 2509
          positive regulation of G protein-coupled receptor signaling pathway 32
            induction by symbiont of host G protein-coupled receptor signal transduction 0
            negative regulation of inhibitory G protein-coupled receptor phosphorylation 0
            positive regulation of adenosine receptor signaling pathway 3
            positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 5
            positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway + 2
            positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 1
            positive regulation of angiotensin-activated signaling pathway 0
            positive regulation of octopamine or tyramine signaling pathway + 0
            positive regulation of opioid receptor signaling pathway + 1
            positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 4
            positive regulation of thrombin-activated receptor signaling pathway 0
Path 2
Term Annotations click to browse term
  biological_process 20028
    biological regulation 13773
      regulation of biological process 13075
        regulation of cellular process 12561
          regulation of cell communication 3480
            positive regulation of cell communication 1927
              positive regulation of signal transduction 1604
                positive regulation of G protein-coupled receptor signaling pathway 32
                  induction by symbiont of host G protein-coupled receptor signal transduction 0
                  negative regulation of inhibitory G protein-coupled receptor phosphorylation 0
                  positive regulation of adenosine receptor signaling pathway 3
                  positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 5
                  positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway + 2
                  positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 1
                  positive regulation of angiotensin-activated signaling pathway 0
                  positive regulation of octopamine or tyramine signaling pathway + 0
                  positive regulation of opioid receptor signaling pathway + 1
                  positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 4
                  positive regulation of thrombin-activated receptor signaling pathway 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.