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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of Notch signaling pathway
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Accession:GO:0045746 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
Synonyms:exact_synonym: down regulation of Notch signaling pathway;   downregulation of Notch signaling pathway;   negative regulation of N signaling pathway;   negative regulation of N signalling pathway;   negative regulation of Notch signalling pathway
 narrow_synonym: inhibition of Notch signaling pathway


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negative regulation of Notch signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
RGD:13792537
RGD:1600115
G Arrdc1 arrestin domain containing 1 JBrowse link 3 2,129,876 2,137,161 RGD:1624291
RGD:1600115
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Bend6 BEN domain containing 6 JBrowse link 9 38,297,253 38,351,312 RGD:1624291
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
G Cbfa2t2 CBFA2/RUNX1 partner transcriptional co-repressor 2 JBrowse link 3 149,935,731 150,041,545 RGD:1624291
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 JBrowse link 3 111,160,205 111,163,425 RGD:1624291
RGD:1600115
G Dlk1 delta like non-canonical Notch ligand 1 JBrowse link 6 133,576,513 133,583,751 RGD:1624291
RGD:13792537
G Dlk2 delta like non-canonical Notch ligand 2 JBrowse link 9 17,061,187 17,065,600 RGD:1624291
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:13792537
G Dll3 delta like canonical Notch ligand 3 JBrowse link 1 85,485,875 85,493,683 RGD:1599776
G Dll4 delta like canonical Notch ligand 4 JBrowse link 3 111,135,011 111,146,746 RGD:1624291
RGD:13792537
G Dlx1 distal-less homeobox 1 JBrowse link 3 58,164,931 58,169,521 RGD:1624291
RGD:1600115
G Dlx2 distal-less homeobox 2 JBrowse link 3 58,180,088 58,181,971 RGD:1624291
RGD:1600115
G Egfl7 EGF-like-domain, multiple 7 JBrowse link 3 4,034,759 4,044,280 RGD:1624291
G Gata2 GATA binding protein 2 JBrowse link 4 120,129,028 120,142,490 RGD:1624291
G Gdpd5 glycerophosphodiester phosphodiesterase domain containing 5 JBrowse link 1 164,337,176 164,418,056 RGD:1624291
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:1624291
RGD:1600115
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor JBrowse link 1 264,309,214 264,319,269 RGD:1624291
RGD:13792537
G Kctd10 potassium channel tetramerization domain containing 10 JBrowse link 12 47,992,079 48,010,531 RGD:1624291
G LOC684871 similar to Protein C8orf4 (Thyroid cancer protein 1) (TC-1) JBrowse link 16 72,388,842 72,390,135 RGD:13792537
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:1624291
RGD:1600115
G Neurl1 neuralized E3 ubiquitin protein ligase 1 JBrowse link 1 266,953,006 267,038,879 RGD:1624291
RGD:13792537
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:1624291
G Notch4 notch receptor 4 JBrowse link 20 4,329,794 4,353,868 RGD:1624291
G Nrarp Notch-regulated ankyrin repeat protein JBrowse link 3 2,396,143 2,398,697 RGD:1624291
RGD:13792537
G Numb NUMB, endocytic adaptor protein JBrowse link 6 107,279,917 107,325,345 RGD:1624291
G Ovol2 ovo-like zinc finger 2 JBrowse link 3 138,433,990 138,464,511 RGD:1624291
G Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase JBrowse link 10 109,963,726 109,966,821 RGD:633801
G Rita1 RBPJ interacting and tubulin associated 1 JBrowse link 12 41,484,970 41,488,889 RGD:1624291
RGD:13792537
RGD:1600115
G Slc35c1 solute carrier family 35 member C1 JBrowse link 3 81,361,080 81,369,010 RGD:1624291
G Tcim transcriptional and immune response regulator JBrowse link 16 72,401,526 72,403,180 RGD:1624291
RGD:13792537
G Tspan15 tetraspanin 15 JBrowse link 20 31,812,558 31,857,191 RGD:1624291
G Zbtb7a zinc finger and BTB domain containing 7a JBrowse link 7 11,429,266 11,446,119 RGD:1600115
RGD:1624291
negative regulation of Notch signaling pathway involved in somitogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase JBrowse link 12 16,117,767 16,126,211 RGD:1624291
RGD:1600115
G Nrarp Notch-regulated ankyrin repeat protein JBrowse link 3 2,396,143 2,398,697 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      signal transduction 6968
        negative regulation of signal transduction 1232
          negative regulation of Notch signaling pathway 36
            negative regulation of Notch signaling pathway involved in somitogenesis 2
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          signal transduction 6968
            cell surface receptor signaling pathway 2772
              Notch signaling pathway 178
                regulation of Notch signaling pathway 87
                  negative regulation of Notch signaling pathway 36
                    negative regulation of Notch signaling pathway involved in somitogenesis 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.