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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of action potential
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Accession:GO:0045759 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
Synonyms:exact_synonym: down regulation of action potential;   downregulation of action potential
 narrow_synonym: inhibition of action potential


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negative regulation of action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:1624291
RGD:1600115
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:2316187
G Cnr2 cannabinoid receptor 2 JBrowse link 5 154,242,010 154,268,126 RGD:2316192
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 JBrowse link 2 50,099,576 50,499,799 RGD:9686419
G Sumo1 small ubiquitin-like modifier 1 JBrowse link 9 66,453,428 66,483,614 RGD:1624291
RGD:1600115
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
RGD:1600115
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:1624291
RGD:1600115
negative regulation of neuronal action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpr35 G protein-coupled receptor 35 JBrowse link 9 100,129,428 100,141,269 RGD:11541107
G Kcnc4 potassium voltage-gated channel subfamily C member 4 JBrowse link 2 210,220,908 210,241,447 RGD:10412022
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link 18 25,163,575 25,222,139 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17883
    negative regulation of biological process 5335
      negative regulation of action potential 10
        negative regulation of AV node cell action potential + 0
        negative regulation of atrial cardiac muscle cell action potential + 0
        negative regulation of membrane depolarization during cardiac muscle cell action potential + 1
        negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
        negative regulation of neuronal action potential 2
        negative regulation of ventricular cardiac muscle cell action potential + 2
Path 2
Term Annotations click to browse term
  biological_process 17883
    biological regulation 12594
      regulation of biological quality 4113
        regulation of membrane potential 464
          action potential 139
            regulation of action potential 62
              negative regulation of action potential 10
                negative regulation of AV node cell action potential + 0
                negative regulation of atrial cardiac muscle cell action potential + 0
                negative regulation of membrane depolarization during cardiac muscle cell action potential + 1
                negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
                negative regulation of neuronal action potential 2
                negative regulation of ventricular cardiac muscle cell action potential + 2
paths to the root