ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of action potential
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Accession:GO:0045759 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
Synonyms:exact_synonym: down regulation of action potential;   downregulation of action potential
 narrow_synonym: inhibition of action potential


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negative regulation of action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 1 133,535,023 133,547,361 RGD:9068941
G CNR1 cannabinoid receptor 1 JBrowse link 6 89,289,102 89,315,174 RGD:9068941
G CNR2 cannabinoid receptor 2 JBrowse link 1 24,046,009 24,135,236 RGD:9068941
G SUMO1 small ubiquitin like modifier 1 JBrowse link 2B 207,613,649 207,645,590 RGD:9068941
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAV3 caveolin 3 JBrowse link 3 8,928,069 8,940,942 RGD:9068941
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 11 72,832,858 72,845,399 RGD:9068941
negative regulation of neuronal action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GPR35 G protein-coupled receptor 35 JBrowse link 2B 246,664,731 246,692,467 RGD:9068941
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BIN1 bridging integrator 1 JBrowse link 2B 127,716,543 127,775,378 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15676
    negative regulation of biological process 5053
      negative regulation of action potential 8
        negative regulation of AV node cell action potential + 0
        negative regulation of atrial cardiac muscle cell action potential + 0
        negative regulation of membrane depolarization during cardiac muscle cell action potential + 1
        negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
        negative regulation of neuronal action potential 1
        negative regulation of ventricular cardiac muscle cell action potential + 2
Path 2
Term Annotations click to browse term
  biological_process 15676
    biological regulation 11110
      regulation of biological quality 3845
        regulation of membrane potential 418
          action potential 124
            regulation of action potential 47
              negative regulation of action potential 8
                negative regulation of AV node cell action potential + 0
                negative regulation of atrial cardiac muscle cell action potential + 0
                negative regulation of membrane depolarization during cardiac muscle cell action potential + 1
                negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
                negative regulation of neuronal action potential 1
                negative regulation of ventricular cardiac muscle cell action potential + 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.