ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of action potential
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Accession:GO:0045759 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
Synonyms:exact_synonym: down regulation of action potential;   downregulation of action potential
 narrow_synonym: inhibition of action potential


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negative regulation of action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link NW_004955545 1,065,457 1,077,056 RGD:9068941
G Cnr1 cannabinoid receptor 1 JBrowse link NW_004955411 15,052,151 15,077,320 RGD:9068941
G Cnr2 cannabinoid receptor 2 JBrowse link NW_004955452 3,763,742 3,795,069 RGD:9068941
G Sumo1 small ubiquitin like modifier 1 JBrowse link NW_004955457 12,538,974 12,565,803 RGD:9068941
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link NW_004955561 326,008 335,911 RGD:9068941
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link NW_004955414 17,166,537 17,200,385 RGD:9068941
negative regulation of neuronal action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpr35 G protein-coupled receptor 35 JBrowse link NW_004955542 851,895 856,688 RGD:9068941
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link NW_004955459 3,376,149 3,423,157 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14516
    negative regulation of biological process 4878
      negative regulation of action potential 8
        negative regulation of AV node cell action potential + 0
        negative regulation of atrial cardiac muscle cell action potential + 0
        negative regulation of membrane depolarization during cardiac muscle cell action potential + 1
        negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
        negative regulation of neuronal action potential 1
        negative regulation of ventricular cardiac muscle cell action potential + 2
Path 2
Term Annotations click to browse term
  biological_process 14516
    biological regulation 10323
      regulation of biological quality 3741
        regulation of membrane potential 412
          action potential 126
            regulation of action potential 48
              negative regulation of action potential 8
                negative regulation of AV node cell action potential + 0
                negative regulation of atrial cardiac muscle cell action potential + 0
                negative regulation of membrane depolarization during cardiac muscle cell action potential + 1
                negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
                negative regulation of neuronal action potential 1
                negative regulation of ventricular cardiac muscle cell action potential + 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.