ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of action potential
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Accession:GO:0045759 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
Synonyms:exact_synonym: down regulation of action potential;   downregulation of action potential
 narrow_synonym: inhibition of action potential


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negative regulation of action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 7 42,786,505 42,797,976 RGD:13508589
RGD:9068941
G CNR1 cannabinoid receptor 1 JBrowse link 12 47,537,240 47,560,723 RGD:9068941
G CNR2 cannabinoid receptor 2 JBrowse link 2 75,640,636 75,662,000 RGD:9068941
G SUMO1 small ubiquitin like modifier 1 JBrowse link 37 11,199,937 11,229,743 RGD:9068941
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAV3 caveolin 3 JBrowse link 20 9,384,901 9,398,055 RGD:13508589
RGD:9068941
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 21 23,860,727 23,872,194 RGD:13508589
RGD:9068941
negative regulation of neuronal action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100855802 G-protein coupled receptor 35-like JBrowse link 25 50,566,263 50,841,473 RGD:9068941
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BIN1 bridging integrator 1 JBrowse link 19 23,503,934 23,534,407 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15735
    negative regulation of biological process 5072
      negative regulation of action potential 8
        negative regulation of AV node cell action potential + 0
        negative regulation of atrial cardiac muscle cell action potential + 0
        negative regulation of membrane depolarization during cardiac muscle cell action potential + 1
        negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
        negative regulation of neuronal action potential 1
        negative regulation of ventricular cardiac muscle cell action potential + 2
Path 2
Term Annotations click to browse term
  biological_process 15735
    biological regulation 11138
      regulation of biological quality 3878
        regulation of membrane potential 424
          action potential 128
            regulation of action potential 51
              negative regulation of action potential 8
                negative regulation of AV node cell action potential + 0
                negative regulation of atrial cardiac muscle cell action potential + 0
                negative regulation of membrane depolarization during cardiac muscle cell action potential + 1
                negative regulation of membrane repolarization during cardiac muscle cell action potential + 1
                negative regulation of neuronal action potential 1
                negative regulation of ventricular cardiac muscle cell action potential + 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.