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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of proteolysis
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Accession:GO:0045861 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Synonyms:exact_synonym: down regulation of proteolysis;   downregulation of proteolysis;   negative regulation of peptidolysis
 narrow_synonym: inhibition of proteolysis


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negative regulation of proteolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
JBrowse link
G Bag6 BAG cochaperone 6 ISO (MGI:MGI:3774040|PMID:18056262) UniProtKB PMID:18056262 MGI:MGI:3774040 NCBI chrNW_004955437:176,848...188,243
Ensembl chrNW_004955437:176,797...188,003
JBrowse link
G Camk2n1 calcium/calmodulin dependent protein kinase II inhibitor 1 ISO (PMID:18305109) UniProtKB PMID:18305109 NCBI chrNW_004955452:1,044,696...1,046,657
Ensembl chrNW_004955452:1,043,459...1,046,669
JBrowse link
G Cdk5 cyclin dependent kinase 5 ISO (PMID:24548080) ParkinsonsUK-UCL PMID:24548080 NCBI chrNW_004955491:5,491,744...5,497,280
Ensembl chrNW_004955491:5,491,744...5,497,280
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:1346962|PMID:10527801) MGI PMID:10527801 MGI:MGI:1346962 NCBI chrNW_004955493:6,696,520...6,707,849 JBrowse link
G Cst3 cystatin C ISO (PMID:3488317) UniProtKB PMID:3488317 NCBI chrNW_004955415:30,507,972...30,512,109 JBrowse link
G Csta cystatin A ISO (PMID:3488317) UniProtKB PMID:3488317 NCBI chrNW_004955427:21,617,099...21,630,712
Ensembl chrNW_004955427:21,617,054...21,630,773
JBrowse link
G Cstb cystatin B ISO (PMID:3488317) UniProtKB PMID:3488317 NCBI chrNW_004955407:41,475,533...41,478,943
Ensembl chrNW_004955407:41,475,533...41,479,150
JBrowse link
G F2 coagulation factor II, thrombin ISO (PMID:1695900) BHF-UCL PMID:1695900 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517
JBrowse link
G Hdac6 histone deacetylase 6 ISO (PMID:18356165) BHF-UCL PMID:18356165 NCBI chrNW_004955543:348,314...378,391
Ensembl chrNW_004955543:348,019...378,071
JBrowse link
G Ide insulin degrading enzyme ISO inhibits activity of the multicatalytic proteinase complex (proteasome) RGD PMID:9000694 RGD:1627643 NCBI chrNW_004955425:819,461...926,440
Ensembl chrNW_004955425:847,615...926,318
JBrowse link
G Ins insulin ISO (PMID:3553851) BHF-UCL PMID:3553851 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419
JBrowse link
G Kng1 kininogen 1 ISO (PMID:3488317) UniProtKB
RGD
PMID:3356189, PMID:3488317 RGD:1600550 NCBI chrNW_004955420:20,989,197...21,016,084 JBrowse link
G Nr1h2 nuclear receptor subfamily 1 group H member 2 ISO (MGI:MGI:3822255|PMID:18806227) BHF-UCL PMID:18806227 MGI:MGI:3822255 NCBI chrNW_004955559:731,630...736,973
Ensembl chrNW_004955559:730,670...737,505
JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 ISO (MGI:MGI:3822255|PMID:18806227) BHF-UCL PMID:18806227 MGI:MGI:3822255 NCBI chrNW_004955422:940,310...954,170
Ensembl chrNW_004955422:940,310...949,049
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:15161606 RGD:1625251 NCBI chrNW_004955446:1,020,707...1,098,327
Ensembl chrNW_004955446:1,020,043...1,098,820
JBrowse link
G Plat plasminogen activator, tissue type ISO (PMID:1695900) BHF-UCL PMID:1695900 NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394
JBrowse link
G Rab23 RAB23, member RAS oncogene family ISO (MGI:MGI:3612806|PMID:16364285) MGI PMID:16364285 MGI:MGI:3612806 NCBI chrNW_004955502:2,947,170...2,980,634
Ensembl chrNW_004955502:2,950,562...2,980,634
JBrowse link
G Serpina5 serpin family A member 5 ISO RGD PMID:16088033 RGD:1580291 NCBI chrNW_004955438:17,787,398...17,796,013
Ensembl chrNW_004955438:17,787,399...17,796,414
JBrowse link
G Serpine2 serpin family E member 2 ISO PMID:17379830
(PMID:17379830), (PMID:3997857)
BHF-UCL PMID:3997857, PMID:17379830 RGD:8553298 NCBI chrNW_004955453:10,049,822...10,076,155
Ensembl chrNW_004955453:10,027,104...10,076,645
JBrowse link
G Spink5 serine peptidase inhibitor Kazal type 5 ISO (MGI:MGI:3055648|PMID:15466487) MGI PMID:15466487 MGI:MGI:3055648 NCBI chrNW_004955415:6,118,616...6,186,632 JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:17532789 RGD:2290425 NCBI chrNW_004955506:3,769,113...3,812,896
Ensembl chrNW_004955506:3,768,646...3,813,820
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO RGD PMID:17532789 RGD:2290425 NCBI chrNW_004955405:41,613,976...41,655,813
Ensembl chrNW_004955405:41,613,966...41,655,813
JBrowse link
G Tm4sf20 transmembrane 4 L six family member 20 ISO (PMID:25310401), (PMID:27499293) UniProtKB PMID:25310401, PMID:27499293 NCBI chrNW_004955453:7,201,738...7,219,322
Ensembl chrNW_004955453:7,201,738...7,219,322
JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:5468878|PMID:23277542) MGI PMID:23277542 MGI:MGI:5468878 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928
JBrowse link
inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin ISO (PMID:2407243) CAFA PMID:2407243 NCBI chrNW_004955418:15,859,951...15,974,141
Ensembl chrNW_004955418:15,862,729...15,916,169
JBrowse link
G Cst7 cystatin F ISO (MGI:MGI:5904382|PMID:28251676) MGI PMID:28251676 MGI:MGI:5904382 NCBI chrNW_004955415:31,082,978...31,086,379
Ensembl chrNW_004955415:31,082,978...31,086,379
JBrowse link
G Nol3 nucleolar protein 3 ISO PMID:16639714
PMID:17292893
UniProt PMID:16639714, PMID:17292893 RGD:10047164, RGD:10047212 NCBI chrNW_004955484:9,443,090...9,447,142
Ensembl chrNW_004955484:9,443,090...9,447,095
JBrowse link
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l12 BCL2 like 12 ISO (PMID:22262180) UniProtKB PMID:22262180 NCBI chrNW_004955559:1,217,797...1,224,875
Ensembl chrNW_004955559:1,217,809...1,224,875
JBrowse link
G Fcmr Fc fragment of IgM receptor ISO (MGI:MGI:3576402|PMID:15632112) MGI PMID:15632112 MGI:MGI:3576402 NCBI chrNW_004955406:42,438,173...42,452,339
Ensembl chrNW_004955406:42,438,783...42,452,163
JBrowse link
G Nol3 nucleolar protein 3 ISO (PMID:15509781) UniProtKB PMID:15509781 NCBI chrNW_004955484:9,443,090...9,447,142
Ensembl chrNW_004955484:9,443,090...9,447,095
JBrowse link
G Xiap X-linked inhibitor of apoptosis ISO (MGI:MGI:2681362|PMID:14623868) MGI PMID:14623868 MGI:MGI:2681362 NCBI chrNW_004955473:10,823,795...10,878,256
Ensembl chrNW_004955473:10,827,435...10,840,604
JBrowse link
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 ISO (PMID:27179792)
(MGI:MGI:5811968|PMID:27179792)
ARUK-UCL PMID:27179792 MGI:MGI:5811968 NCBI chrNW_004955459:3,376,149...3,423,157
Ensembl chrNW_004955459:3,399,611...3,422,621
JBrowse link
G Sorl1 sortilin related receptor 1 ISO (MGI:MGI:3801250|PMID:18362153)
(PMID:16407538)
(PMID:17855360), (PMID:21989385)
Alzheimers_University_of_Toronto PMID:16407538, PMID:17855360, PMID:18362153, PMID:21989385 MGI:MGI:3801250 NCBI chrNW_004955412:22,421,984...22,576,179
Ensembl chrNW_004955412:22,421,984...22,576,179
JBrowse link
negative regulation of cysteine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csn2 casein beta ISO (PMID:12788072) CAFA PMID:12788072 NCBI chrNW_004955447:2,868,899...2,889,969 JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:23690069 RGD:13792722 NCBI chrNW_004955422:18,173,438...18,192,357
Ensembl chrNW_004955422:18,170,616...18,192,412
JBrowse link
G Htt huntingtin ISO RGD PMID:17124493 RGD:6902918 NCBI chrNW_004955514:1,906,189...2,042,357
Ensembl chrNW_004955514:1,906,502...2,038,889
JBrowse link
G Ifi16 interferon gamma inducible protein 16 ISO (PMID:22046441) UniProtKB PMID:22046441 NCBI chrNW_004955468:10,828,726...10,845,853 JBrowse link
G Ltf lactotransferrin ISO (PMID:12788072) CAFA PMID:12788072 NCBI chrNW_004955420:25,580,449...25,604,277
Ensembl chrNW_004955420:25,580,359...25,604,331
JBrowse link
G Pcid2 PCI domain containing 2 ISO (PMID:20870947) UniProtKB PMID:20870947 NCBI chrNW_004955404:618,092...639,424
Ensembl chrNW_004955404:618,092...639,704
JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO RGD PMID:15211592 RGD:1625666 NCBI chrNW_004955455:7,886,720...7,906,214
Ensembl chrNW_004955455:7,895,974...7,906,505
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO (MGI:MGI:5294538|PMID:18977203) UniProtKB PMID:18977203 MGI:MGI:5294538 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO caspase 3 RGD PMID:18348079 RGD:2313324 NCBI chrNW_004955578:950,258...1,004,438 JBrowse link
G Aqp1 aquaporin 1 (Colton blood group) ISO (PMID:21215257) UniProtKB PMID:21215257 NCBI chrNW_004955410:32,066,196...32,078,661 JBrowse link
G Arl6ip1 ADP ribosylation factor like GTPase 6 interacting protein 1 ISO (PMID:12754298) UniProtKB PMID:12754298 NCBI chrNW_004955442:2,540,676...2,550,531 JBrowse link
G Arrb1 arrestin beta 1 ISO (MGI:MGI:4453294|PMID:19915011) UniProtKB PMID:19915011 MGI:MGI:4453294 NCBI chrNW_004955414:16,478,843...16,568,050
Ensembl chrNW_004955414:16,478,843...16,562,135
JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:19171933 RGD:5510006 NCBI chrNW_004955467:10,109,985...10,118,687
Ensembl chrNW_004955467:10,110,003...10,123,022
JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO (PMID:19047049) UniProtKB PMID:19047049 NCBI chrNW_004955422:11,106,061...11,189,951 JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D ISO (PMID:15750620) BHF-UCL PMID:15750620 NCBI chrNW_004955495:1,755,280...1,759,125
Ensembl chrNW_004955495:1,755,878...1,757,037
JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator ISO (MGI:MGI:3612311|PMID:16263940) MGI PMID:16263940 MGI:MGI:3612311 NCBI chrNW_004955403:415,092...442,214
Ensembl chrNW_004955403:412,632...434,741
JBrowse link
G Cryaa crystallin alpha A ISO (MGI:MGI:3617146|PMID:16439475) MGI PMID:16439475 MGI:MGI:3617146 NCBI chrNW_004955407:38,880,088...38,892,946 JBrowse link
G Cryab crystallin alpha B ISO (MGI:MGI:3617146|PMID:16439475) MGI PMID:16439475 MGI:MGI:3617146 NCBI chrNW_004955412:13,626,018...13,629,495
Ensembl chrNW_004955412:13,625,363...13,640,426
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 ISO (PMID:16193064) UniProtKB PMID:16193064 NCBI chrNW_004955597:326,601...397,112 JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked ISO (PMID:18846110) UniProtKB PMID:18846110 NCBI chrNW_004955565:1,387,043...1,403,624
Ensembl chrNW_004955565:1,386,973...1,404,220
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase ISO (PMID:11007892) UniProtKB PMID:11007892 NCBI chrNW_004955464:4,533,928...4,557,893
Ensembl chrNW_004955464:4,533,928...4,558,133
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 ISO (PMID:10411904) UniProtKB PMID:10411904 NCBI chrNW_004955442:12,971,031...13,002,605
Ensembl chrNW_004955442:12,967,438...13,010,943
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 ISO (PMID:11896048) UniProtKB PMID:11896048 NCBI chrNW_004955579:240,058...298,592 JBrowse link
G Dpep1 dipeptidase 1 ISO (PMID:20435919) UniProtKB PMID:20435919 NCBI chrNW_004955541:3,204,421...3,215,514
Ensembl chrNW_004955541:3,204,055...3,215,565
JBrowse link
G Ep300 E1A binding protein p300 ISO cardiac myocytes RGD PMID:22562121 RGD:7327216 NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933
JBrowse link
G Fnip1 folliculin interacting protein 1 ISO (MGI:MGI:5444323|PMID:22709692) MGI PMID:22709692 MGI:MGI:5444323 NCBI chrNW_004955408:3,117,258...3,238,223
Ensembl chrNW_004955408:3,117,277...3,238,223
JBrowse link
G Gas6 growth arrest specific 6 ISO (PMID:16723520) UniProtKB PMID:16723520 NCBI chrNW_004955404:276,397...303,864
Ensembl chrNW_004955404:275,946...304,809
JBrowse link
G Gpi glucose-6-phosphate isomerase ISO RGD PMID:12615053 RGD:1600634 NCBI chrNW_004955468:3,980,999...4,007,553
Ensembl chrNW_004955468:3,980,999...4,008,652
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO (PMID:12221075) BHF-UCL PMID:12221075 NCBI chrNW_004955532:1,298,336...1,298,830 JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 ISO RGD PMID:15102845 RGD:1304324 NCBI chrNW_004955433:14,609,275...14,621,774
Ensembl chrNW_004955433:14,608,375...14,621,839
JBrowse link
G Hgf hepatocyte growth factor ISO (PMID:20655899) BHF-UCL PMID:20655899 NCBI chrNW_004955410:4,114,280...4,181,953
Ensembl chrNW_004955410:4,114,778...4,182,058
JBrowse link
G Igbp1 immunoglobulin binding protein 1 ISO (PMID:17438131) UniProtKB PMID:17438131 NCBI chrNW_004955475:9,671,162...9,694,926 JBrowse link
G Igf1 insulin like growth factor 1 ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Il24 interleukin 24 ISO (MGI:MGI:3821693|PMID:18708357) MGI PMID:18708357 MGI:MGI:3821693 NCBI chrNW_004955406:42,431,845...42,437,392
Ensembl chrNW_004955406:42,432,795...42,437,016
JBrowse link
G Il6 interleukin 6 ISO RGD PMID:19061939 RGD:2306937 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Ints1 integrator complex subunit 1 ISO (MGI:MGI:3722560|PMID:17544522) MGI PMID:17544522 MGI:MGI:3722560 NCBI chrNW_004955460:9,116,650...9,149,470
Ensembl chrNW_004955460:9,116,891...9,143,120
JBrowse link
G Klf4 Kruppel like factor 4 ISO (PMID:20551324) BHF-UCL PMID:20551324 NCBI chrNW_004955419:19,280,311...19,284,097
Ensembl chrNW_004955419:19,280,235...19,285,174
JBrowse link
G Lamp3 lysosomal associated membrane protein 3 ISO (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chrNW_004955420:24,155,793...24,185,366 JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 ISO (PMID:12773388) UniProtKB PMID:12773388 NCBI chrNW_004955435:13,896,320...13,900,742
Ensembl chrNW_004955435:13,896,320...13,900,754
JBrowse link
G Map2k5 mitogen-activated protein kinase kinase 5 ISO PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chrNW_004955450:8,207,577...8,458,258
Ensembl chrNW_004955450:8,203,569...8,458,258
JBrowse link
G Mdm2 MDM2 proto-oncogene ISO caspase-2, caspase-3 RGD PMID:19850968 RGD:2317361 NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808
JBrowse link
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 ISO (MGI:MGI:5142343|PMID:21730291) UniProtKB PMID:21730291 MGI:MGI:5142343 NCBI chrNW_004955411:34,484,536...34,495,154
Ensembl chrNW_004955411:34,484,653...34,493,877
JBrowse link
G Mrtfa myocardin related transcription factor A ISO (MGI:MGI:2183867|PMID:12019265) MGI PMID:12019265 MGI:MGI:2183867 NCBI chrNW_004955413:26,139,060...26,311,272
Ensembl chrNW_004955413:26,139,843...26,222,580
JBrowse link
G Naip NLR family apoptosis inhibitory protein ISO (PMID:11896143) UniProtKB PMID:11896143 NCBI chrNW_004955575:249,659...283,378 JBrowse link
G Nol3 nucleolar protein 3 ISO PMID:19001025 UniProt PMID:19001025 RGD:8553292 NCBI chrNW_004955484:9,443,090...9,447,142
Ensembl chrNW_004955484:9,443,090...9,447,095
JBrowse link
G Nr4a1 nuclear receptor subfamily 4 group A member 1 ISO (MGI:MGI:2667579|PMID:12815108) MGI PMID:12815108 MGI:MGI:2667579 NCBI chrNW_004955547:2,404,532...2,426,882
Ensembl chrNW_004955547:2,404,532...2,431,050
JBrowse link
G Pax2 paired box 2 ISO (PMID:10980123), (PMID:17357786) UniProtKB PMID:10980123, PMID:17357786 NCBI chrNW_004955485:9,351,913...9,430,607
Ensembl chrNW_004955485:9,350,087...9,430,607
JBrowse link
G Por P450 (cytochrome) oxidoreductase ISO caspase-3 RGD PMID:19264869 RGD:2316785 NCBI chrNW_004955456:14,698,589...14,748,520
Ensembl chrNW_004955456:14,698,589...14,748,520
JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO (PMID:21716255) CAFA PMID:21716255 NCBI chrNW_004955409:10,760,801...10,775,197
Ensembl chrNW_004955409:10,757,888...10,774,688
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO (MGI:MGI:5474549|PMID:21716255) CAFA PMID:21716255 MGI:MGI:5474549 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
JBrowse link
G Ptma prothymosin alpha ISO RGD PMID:12522243 RGD:734494 NCBI chrNW_004955453:4,036,503...4,037,788 JBrowse link
G Rag1 recombination activating 1 ISO (MGI:MGI:3531056|PMID:15728238) MGI PMID:15728238 MGI:MGI:3531056 NCBI chrNW_004955422:9,891,878...9,928,569
Ensembl chrNW_004955422:9,891,878...9,919,504
JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 ISO (PMID:18402937) UniProtKB PMID:18402937 NCBI chrNW_004955452:5,905,561...5,938,096
Ensembl chrNW_004955452:5,904,762...5,939,091
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 ISO (PMID:18402937) UniProtKB PMID:18402937 NCBI chrNW_004955509:600,415...701,833
Ensembl chrNW_004955509:600,284...701,837
JBrowse link
G Sfn stratifin ISO (PMID:11574543) HGNC PMID:11574543 NCBI chrNW_004955452:6,217,519...6,218,481
Ensembl chrNW_004955452:6,217,698...6,218,444
JBrowse link
G Sfrp2 secreted frizzled related protein 2 ISO (MGI:MGI:3702339|PMID:17251350) MGI PMID:17251350 MGI:MGI:3702339 NCBI chrNW_004955471:8,103,937...8,112,596
Ensembl chrNW_004955471:8,103,783...8,112,321
JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 ISO (PMID:21586138) UniProtKB PMID:21586138 NCBI chrNW_004955403:36,989,509...37,141,188
Ensembl chrNW_004955403:36,988,811...37,142,401
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 ISO (PMID:21586138) UniProtKB PMID:21586138 NCBI chrNW_004955448:1,907,478...1,926,445
Ensembl chrNW_004955448:1,907,401...1,926,445
JBrowse link
G Snca synuclein alpha ISO (PMID:10818098) UniProtKB PMID:10818098 NCBI chrNW_004955405:854,011...962,741
Ensembl chrNW_004955405:853,946...965,403
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO (PMID:19767770) UniProtKB PMID:19767770 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695
JBrowse link
G Thbs1 thrombospondin 1 ISO (PMID:18653767) UniProtKB PMID:18653767 NCBI chrNW_004955416:6,490,034...6,506,419
Ensembl chrNW_004955416:6,489,451...6,506,419
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:31124343) ARUK-UCL PMID:31124343 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 ISO (PMID:15735003) BHF-UCL PMID:15735003 NCBI chrNW_004955455:11,195,399...11,198,402
Ensembl chrNW_004955455:11,195,399...11,198,402
JBrowse link
G Usp47 ubiquitin specific peptidase 47 ISO (PMID:19966869) UniProtKB PMID:19966869 NCBI chrNW_004955414:27,357,602...27,462,481
Ensembl chrNW_004955414:27,357,602...27,462,731
JBrowse link
G Vegfa vascular endothelial growth factor A ISO (PMID:18386220) UniProtKB PMID:18386220 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
G Wnt9a Wnt family member 9A ISO (MGI:MGI:4368092|PMID:19422823) MGI PMID:19422823 MGI:MGI:4368092 NCBI chrNW_004955581:422,028...438,321
Ensembl chrNW_004955581:421,451...438,380
JBrowse link
G Xiap X-linked inhibitor of apoptosis ISO (MGI:MGI:2183141|PMID:12011074), (MGI:MGI:2183348|PMID:12153481)
(PMID:11583623)
MGI
UniProtKB
PMID:11583623, PMID:12011074, PMID:12153481 MGI:MGI:2183141, MGI:MGI:2183348 NCBI chrNW_004955473:10,823,795...10,878,256
Ensembl chrNW_004955473:10,827,435...10,840,604
JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Caap1 caspase activity and apoptosis inhibitor 1 ISO (PMID:21980415) UniProtKB PMID:21980415 NCBI chrNW_004955472:7,937,702...7,993,252
Ensembl chrNW_004955472:7,937,866...7,992,440
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO (PMID:22984561) CACAO PMID:22984561 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
JBrowse link
G Nle1 notchless homolog 1 ISO (MGI:MGI:5468737|PMID:23231322) MGI PMID:23231322 MGI:MGI:5468737 NCBI chrNW_004955481:9,821,329...9,830,350
Ensembl chrNW_004955481:9,821,329...9,830,555
JBrowse link
G Park7 Parkinsonism associated deglycase ISO (PMID:21785459) ParkinsonsUK-UCL PMID:21785459 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885
JBrowse link
G Pih1d1 PIH1 domain containing 1 ISO (PMID:21078300) UniProtKB PMID:21078300 NCBI chrNW_004955559:1,390,823...1,395,550
Ensembl chrNW_004955559:1,391,314...1,396,329
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO (PMID:22984561) CACAO PMID:22984561 NCBI chrNW_004955555:1,378,505...1,393,395
Ensembl chrNW_004955555:1,378,793...1,393,324
JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pak2 p21 (RAC1) activated kinase 2 ISO (PMID:21555521) UniProtKB PMID:21555521 NCBI chrNW_004955420:12,893,760...12,930,955
Ensembl chrNW_004955420:12,892,845...12,930,955
JBrowse link
G Rffl ring finger and FYVE like domain containing E3 ubiquitin protein ligase ISO (PMID:15069192) UniProtKB PMID:15069192 NCBI chrNW_004955481:9,718,369...9,788,048 JBrowse link
G Rnf34 ring finger protein 34 ISO (PMID:15069192) UniProtKB PMID:15069192 NCBI chrNW_004955482:6,889,112...6,905,139
Ensembl chrNW_004955482:6,891,546...6,905,139
JBrowse link
negative regulation of endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
JBrowse link
G Crb2 crumbs cell polarity complex component 2 ISO (PMID:20299451) UniProtKB PMID:20299451 NCBI chrNW_004955419:4,604,883...4,626,675
Ensembl chrNW_004955419:4,607,507...4,626,608
JBrowse link
G Fetub fetuin B ISO (MGI:MGI:5488517|PMID:23562279) UniProtKB PMID:23562279 MGI:MGI:5488517 NCBI chrNW_004955420:21,041,419...21,054,043
Ensembl chrNW_004955420:21,040,621...21,054,391
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO (PMID:22832495) UniProtKB PMID:22832495 NCBI chrNW_004955413:4,162,467...4,166,783
Ensembl chrNW_004955413:4,162,467...4,166,783
JBrowse link
G LOC102021956 alpha-2-macroglobulin ISO RGD PMID:19240864 RGD:7411612 NCBI chrNW_004955413:6,019,457...6,062,366
Ensembl chrNW_004955413:6,019,082...6,062,529
JBrowse link
G Renbp renin binding protein ISO RGD PMID:11926999 RGD:727355 NCBI chrNW_004955580:610,112...615,019
Ensembl chrNW_004955580:609,964...615,027
JBrowse link
G Serpinb1 serpin family B member 1 ISO (PMID:30692621) UniProt PMID:30692621 NCBI chrNW_004955465:10,541,562...10,551,417
Ensembl chrNW_004955465:10,541,485...10,550,290
JBrowse link
G Serpinb13 serpin family B member 13 ISO (PMID:12504904) UniProtKB PMID:12504904 NCBI chrNW_004955402:47,376,973...47,395,267 JBrowse link
G Serpinb8 serpin family B member 8 ISO (PMID:8530382) UniProtKB PMID:8530382 NCBI chrNW_004955402:47,761,900...47,781,281
Ensembl chrNW_004955402:47,763,322...47,781,523
JBrowse link
G Serpine1 serpin family E member 1 ISO (PMID:1695900) BHF-UCL
RGD
PMID:1695900, PMID:10717410 RGD:8547889 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142
JBrowse link
G Spock1 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 ISO (PMID:14511383) UniProtKB PMID:14511383 NCBI chrNW_004955408:31,954,622...32,465,463
Ensembl chrNW_004955408:31,957,882...32,465,461
JBrowse link
G Spock3 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 ISO (PMID:11751414) UniProtKB PMID:11751414 NCBI chrNW_004955403:38,476,251...38,870,760
Ensembl chrNW_004955403:38,476,182...38,873,299
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO (PMID:3903517) UniProtKB PMID:3903517 NCBI chrNW_004955516:507,113...511,360
Ensembl chrNW_004955516:505,789...512,118
JBrowse link
G Vtn vitronectin ISO (PMID:1695900) BHF-UCL PMID:1695900 NCBI chrNW_004955481:4,765,078...4,768,027 JBrowse link
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sgta small glutamine rich tetratricopeptide repeat containing alpha ISO (PMID:23129660) UniProtKB PMID:23129660 NCBI chrNW_004955495:5,025,038...5,051,810
Ensembl chrNW_004955495:5,031,229...5,052,389
JBrowse link
G Svip small VCP interacting protein ISO (PMID:17872946) UniProtKB PMID:17872946 NCBI chrNW_004955476:3,231,789...3,236,602 JBrowse link
G Usp14 ubiquitin specific peptidase 14 ISO (PMID:19135427) ParkinsonsUK-UCL PMID:19135427 NCBI chrNW_004955402:9,710,080...9,737,601
Ensembl chrNW_004955402:9,710,080...9,743,077
JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp11 aquaporin 11 ISO (MGI:MGI:3813160|PMID:18606867) UniProt PMID:18606867 MGI:MGI:3813160 NCBI chrNW_004955414:14,245,682...14,260,717
Ensembl chrNW_004955414:14,245,682...14,260,717
JBrowse link
G Ubxn1 UBX domain protein 1 ISO (PMID:21135095) ParkinsonsUK-UCL PMID:21135095 NCBI chrNW_004955599:526,792...529,825
Ensembl chrNW_004955599:526,966...529,735
JBrowse link
G Usp25 ubiquitin specific peptidase 25 ISO (PMID:22590560) ParkinsonsUK-UCL PMID:22590560 NCBI chrNW_004955407:17,429,299...17,572,138
Ensembl chrNW_004955407:17,429,299...17,575,262
JBrowse link
negative regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 ISO (PMID:18383040) BHF-UCL PMID:18383040 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Lrig2 leucine rich repeats and immunoglobulin like domains 2 ISO (MGI:MGI:5702499|PMID:26651291) MGI PMID:26651291 MGI:MGI:5702499 NCBI chrNW_004955435:16,468,300...16,522,503
Ensembl chrNW_004955435:16,468,509...16,521,868
JBrowse link
G Ptpn3 protein tyrosine phosphatase non-receptor type 3 ISO (PMID:12207026) BHF-UCL PMID:12207026 NCBI chrNW_004955419:17,560,664...17,645,420
Ensembl chrNW_004955419:17,493,518...17,645,477
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO (PMID:12714508) UniProtKB PMID:12714508 NCBI chrNW_004955516:507,113...511,360
Ensembl chrNW_004955516:505,789...512,118
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO (PMID:18383040) BHF-UCL PMID:18383040 NCBI chrNW_004955405:41,613,976...41,655,813
Ensembl chrNW_004955405:41,613,966...41,655,813
JBrowse link
negative regulation of metalloendopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Reck reversion inducing cysteine rich protein with kazal motifs ISO (PMID:18194466)
(MGI:MGI:5659805|PMID:24812324)
UniProt
BHF-UCL
PMID:18194466, PMID:24812324 MGI:MGI:5659805 NCBI chrNW_004955472:222,261...276,869
Ensembl chrNW_004955472:223,683...287,089
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO (MGI:MGI:5659805|PMID:24812324) BHF-UCL PMID:24812324 MGI:MGI:5659805 NCBI chrNW_004955405:41,613,976...41,655,813
Ensembl chrNW_004955405:41,613,966...41,655,813
JBrowse link
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Picalm phosphatidylinositol binding clathrin assembly protein ISO (MGI:MGI:5432454|PMID:22539346) Alzheimers_University_of_Toronto PMID:22539346 MGI:MGI:5432454 NCBI chrNW_004955414:6,871,220...6,970,569
Ensembl chrNW_004955414:6,871,520...6,969,208
JBrowse link
G Sorl1 sortilin related receptor 1 ISO (MGI:MGI:3801250|PMID:18362153)
(PMID:17855360), (PMID:21989385)
Alzheimers_University_of_Toronto PMID:17855360, PMID:18362153, PMID:21989385 MGI:MGI:3801250 NCBI chrNW_004955412:22,421,984...22,576,179
Ensembl chrNW_004955412:22,421,984...22,576,179
JBrowse link
negative regulation of metallopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Timp1 TIMP metallopeptidase inhibitor 1 ISO (PMID:9573338) UniProtKB PMID:9573338 NCBI chrNW_004955516:507,113...511,360
Ensembl chrNW_004955516:505,789...512,118
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO (PMID:9573338) UniProtKB PMID:9573338 NCBI chrNW_004955506:3,769,113...3,812,896
Ensembl chrNW_004955506:3,768,646...3,813,820
JBrowse link
negative regulation of peptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin ISO (MGI:MGI:5295525|PMID:21849499) MGI PMID:21849499 MGI:MGI:5295525 NCBI chrNW_004955418:15,859,951...15,974,141
Ensembl chrNW_004955418:15,862,729...15,916,169
JBrowse link
G Cst3 cystatin C ISO (PMID:18256700), (PMID:6203523), (PMID:7890620) ARUK-UCL PMID:6203523, PMID:7890620, PMID:18256700 NCBI chrNW_004955415:30,507,972...30,512,109 JBrowse link
G Cst7 cystatin F ISO (PMID:15752368), (PMID:18256700), (PMID:22365146)
(MGI:MGI:6294189|PMID:18256700)
ARUK-UCL PMID:15752368, PMID:18256700, PMID:22365146 MGI:MGI:6294189 NCBI chrNW_004955415:31,082,978...31,086,379
Ensembl chrNW_004955415:31,082,978...31,086,379
JBrowse link
G Csta cystatin A ISO (PMID:6203523) BHF-UCL PMID:6203523 NCBI chrNW_004955427:21,617,099...21,630,712
Ensembl chrNW_004955427:21,617,054...21,630,773
JBrowse link
G Cstb cystatin B ISO (PMID:6203523) BHF-UCL PMID:6203523 NCBI chrNW_004955407:41,475,533...41,478,943
Ensembl chrNW_004955407:41,475,533...41,479,150
JBrowse link
G Ecm1 extracellular matrix protein 1 ISO (PMID:16512877) UniProtKB PMID:16512877 NCBI chrNW_004955413:293,295...299,293
Ensembl chrNW_004955413:290,363...299,130
JBrowse link
G Serpine2 serpin family E member 2 ISO (MGI:MGI:3521551|PMID:15509762), (MGI:MGI:3810206|PMID:18398001) MGI PMID:15509762, PMID:18398001 MGI:MGI:3521551, MGI:MGI:3810206 NCBI chrNW_004955453:10,049,822...10,076,155
Ensembl chrNW_004955453:10,027,104...10,076,645
JBrowse link
G Spink1 serine peptidase inhibitor Kazal type 1 ISO (MGI:MGI:72783|PMID:3428272) MGI PMID:3428272 MGI:MGI:72783 NCBI chrNW_004955415:6,328,672...6,378,611
Ensembl chrNW_004955415:6,371,059...6,378,529
JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpb2 carboxypeptidase B2 ISO RGD PMID:23369837 RGD:7243115 NCBI chrNW_004955518:3,740,348...3,803,540
Ensembl chrNW_004955518:3,740,348...3,803,539
JBrowse link
G Ctsz cathepsin Z ISO (PMID:19433310) CAFA PMID:19433310 NCBI chrNW_004955445:586,901...597,753
Ensembl chrNW_004955445:586,902...597,753
JBrowse link
G Serpine1 serpin family E member 1 ISO (PMID:18835034), (PMID:19855083)
(PMID:8508955)
(MGI:MGI:4418017|PMID:19855083)
BHF-UCL PMID:8508955, PMID:18835034, PMID:19855083 MGI:MGI:4418017 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142
JBrowse link
G Serpine2 serpin family E member 2 ISO (PMID:19855083)
(MGI:MGI:4418017|PMID:19855083)
BHF-UCL PMID:19855083 MGI:MGI:4418017 NCBI chrNW_004955453:10,049,822...10,076,155
Ensembl chrNW_004955453:10,027,104...10,076,645
JBrowse link
G Serpinf2 serpin family F member 2 ISO (PMID:134998) BHF-UCL PMID:134998 NCBI chrNW_004955481:1,441,262...1,449,078
Ensembl chrNW_004955481:1,442,010...1,449,242
JBrowse link
G Thbs1 thrombospondin 1 ISO (PMID:6438154) BHF-UCL PMID:6438154 NCBI chrNW_004955416:6,490,034...6,506,419
Ensembl chrNW_004955416:6,489,451...6,506,419
JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase ISO (PMID:8175643) CAFA PMID:8175643 NCBI chrNW_004955419:14,093,010...14,104,376
Ensembl chrNW_004955419:14,093,010...14,104,545
JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 ISO (PMID:21669198) BHF-UCL PMID:21669198 NCBI chrNW_004955484:1,991,020...2,004,925
Ensembl chrNW_004955484:1,991,020...2,004,925
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO PMID:17517623
(MGI:MGI:6148636|PMID:17517623)
ARUK-UCL PMID:17517623 MGI:MGI:6148636, RGD:13514081 NCBI chrNW_004955437:9,872,649...9,878,459
Ensembl chrNW_004955437:9,873,908...9,878,459
JBrowse link
G Lamp3 lysosomal associated membrane protein 3 ISO (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chrNW_004955420:24,155,793...24,185,366 JBrowse link
G LOC102030058 protein SCO1 homolog, mitochondrial ISO (MGI:MGI:5643882|PMID:25683716) MGI PMID:25683716 MGI:MGI:5643882 NCBI chrNW_004955467:6,519,873...6,535,321
Ensembl chrNW_004955467:6,519,873...6,537,753
JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 ISO (PMID:29295817) UniProtKB PMID:29295817 NCBI chrNW_004955449:13,834,561...13,875,864
Ensembl chrNW_004955449:13,835,811...13,859,699
JBrowse link
G Ophn1 oligophrenin 1 ISO (MGI:MGI:5303043|PMID:21874017) UniProtKB PMID:21874017 MGI:MGI:5303043 NCBI chrNW_004955475:7,576,629...8,019,132
Ensembl chrNW_004955475:7,581,675...8,018,139
JBrowse link
G Prkcg protein kinase C gamma ISO (MGI:MGI:5467682|PMID:23185022) UniProtKB PMID:23185022 MGI:MGI:5467682 NCBI chrNW_004955604:262,182...279,259
Ensembl chrNW_004955604:262,071...279,259
JBrowse link
G Psme3ip1 proteasome activator subunit 3 interacting protein 1 ISO (PMID:29934401) UniProt PMID:29934401 NCBI chrNW_004955433:14,813,688...14,843,446
Ensembl chrNW_004955433:14,813,688...14,843,223
JBrowse link
G Psmf1 proteasome inhibitor subunit 1 ISO (PMID:10764772) UniProtKB PMID:10764772 NCBI chrNW_004955596:381,080...414,307
Ensembl chrNW_004955596:381,068...416,055
JBrowse link
G Usp19 ubiquitin specific peptidase 19 ISO (MGI:MGI:5614537|PMID:25088257) ParkinsonsUK-UCL PMID:25088257 MGI:MGI:5614537 NCBI chrNW_004955532:1,104,212...1,115,267
Ensembl chrNW_004955532:1,104,591...1,113,567
JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 ISO (PMID:24475098) ParkinsonsUK-UCL PMID:24475098 NCBI chrNW_004955538:2,412,297...2,416,094
Ensembl chrNW_004955538:2,412,297...2,415,132
JBrowse link
G Bag6 BAG cochaperone 6 ISO (MGI:MGI:3808636|PMID:18678708) UniProtKB PMID:18678708 MGI:MGI:3808636 NCBI chrNW_004955437:176,848...188,243
Ensembl chrNW_004955437:176,797...188,003
JBrowse link
G Camlg calcium modulating ligand ISO (PMID:20553626) UniProt PMID:20553626 NCBI chrNW_004955408:29,968,962...29,977,896
Ensembl chrNW_004955408:29,968,934...29,979,794
JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 ISO (PMID:23398316) UniProtKB PMID:23398316 NCBI chrNW_004955403:46,027,997...46,042,154
Ensembl chrNW_004955403:46,027,998...46,042,154
JBrowse link
G Clec16a C-type lectin domain containing 16A ISO (MGI:MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:MGI:5603233 NCBI chrNW_004955442:7,369,616...7,584,052
Ensembl chrNW_004955442:7,368,952...7,584,703
JBrowse link
G Ddrgk1 DDRGK domain containing 1 ISO (PMID:28263186) UniProtKB PMID:28263186 NCBI chrNW_004955415:14,085,404...14,098,220
Ensembl chrNW_004955415:14,085,404...14,098,856
JBrowse link
G Eif3h eukaryotic translation initiation factor 3 subunit H ISO (PMID:32269044) FlyBase PMID:32269044 NCBI chrNW_004955417:22,757,781...22,846,349
Ensembl chrNW_004955417:22,754,395...22,846,618
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO (PMID:15313915) UniProtKB PMID:15313915 NCBI chrNW_004955430:221,518...508,094 JBrowse link
G Gipc1 GIPC PDZ domain containing family member 1 ISO (MGI:MGI:3807767|PMID:11546783) BHF-UCL PMID:11546783 MGI:MGI:3807767 NCBI chrNW_004955415:33,067,689...33,077,749
Ensembl chrNW_004955415:33,067,689...33,074,730
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO (PMID:16280321)
(PMID:24613385)
MGI
UniProtKB
PMID:16280321, PMID:24613385 NCBI chrNW_004955437:9,872,649...9,878,459
Ensembl chrNW_004955437:9,873,908...9,878,459
JBrowse link
G Klhl40 kelch like family member 40 ISO (MGI:MGI:5586592|PMID:24960163) MGI PMID:24960163 MGI:MGI:5586592 NCBI chrNW_004955420:28,117,553...28,122,391
Ensembl chrNW_004955420:28,117,898...28,122,270
JBrowse link
G Map1a microtubule associated protein 1A ISO (MGI:MGI:5703671|PMID:26609151) ARUK-UCL PMID:26609151 MGI:MGI:5703671 NCBI chrNW_004955416:10,052,964...10,073,318
Ensembl chrNW_004955416:10,053,010...10,071,421
JBrowse link
G Mtm1 myotubularin 1 ISO (MGI:MGI:5510937|PMID:23695157) MGI PMID:23695157 MGI:MGI:5510937 NCBI chrNW_004955498:6,329,402...6,444,708
Ensembl chrNW_004955498:6,329,275...6,445,169
JBrowse link
G N4bp1 NEDD4 binding protein 1 ISO (MGI:MGI:3829128|PMID:17592138) UniProtKB PMID:17592138 MGI:MGI:3829128 NCBI chrNW_004955474:6,796,068...6,814,906
Ensembl chrNW_004955474:6,796,066...6,814,906
JBrowse link
G Nop53 NOP53 ribosome biogenesis factor ISO (PMID:22522597) UniProtKB PMID:22522597 NCBI chrNW_004955574:1,505,997...1,514,680
Ensembl chrNW_004955574:1,506,022...1,517,130
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase ISO (PMID:26678539) UniProtKB PMID:26678539 NCBI chrNW_004955475:11,062,258...11,112,252
Ensembl chrNW_004955475:11,062,076...11,114,169
JBrowse link
G Park7 Parkinsonism associated deglycase ISO (PMID:17015834) ParkinsonsUK-UCL PMID:17015834 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885
JBrowse link
G Pbk PDZ binding kinase ISO (MGI:MGI:5293269|PMID:21715333) MGI PMID:21715333 MGI:MGI:5293269 NCBI chrNW_004955403:50,332,167...50,353,147
Ensembl chrNW_004955403:50,330,981...50,352,570
JBrowse link
G Rpl11 ribosomal protein L11 ISO (MGI:MGI:5897550|PMID:21804542) UniProtKB PMID:21804542 MGI:MGI:5897550 NCBI chrNW_004955452:3,626,609...3,630,911
Ensembl chrNW_004955452:3,626,609...3,633,209
JBrowse link
G Rybp RING1 and YY1 binding protein ISO (PMID:27060496) UniProtKB PMID:27060496 NCBI chrNW_004955421:15,728,778...15,803,150
Ensembl chrNW_004955421:15,728,580...15,803,150
JBrowse link
G Sdcbp syndecan binding protein ISO (PMID:25893292) UniProtKB PMID:25893292 NCBI chrNW_004955454:17,093,930...17,113,491
Ensembl chrNW_004955454:17,089,232...17,113,484
JBrowse link
G Senp1 SUMO specific peptidase 1 ISO (MGI:MGI:3818351|PMID:17981124) MGI PMID:17981124 MGI:MGI:3818351 NCBI chrNW_004955500:6,924,445...6,978,482
Ensembl chrNW_004955500:6,926,548...6,979,230
JBrowse link
G Shh sonic hedgehog signaling molecule ISO (MGI:MGI:3624046|PMID:16611981) MGI PMID:16611981 MGI:MGI:3624046 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 ISO (MGI:MGI:5310666|PMID:22285184) MGI PMID:22285184 MGI:MGI:5310666 NCBI chrNW_004955420:24,594,057...24,729,108
Ensembl chrNW_004955420:24,593,830...24,729,108
JBrowse link
G Taf9 TATA-box binding protein associated factor 9 ISO (PMID:11278372) BHF-UCL PMID:11278372 NCBI chrNW_004955575:74,506...76,272
Ensembl chrNW_004955575:74,506...76,272
JBrowse link
G Tlk2 tousled like kinase 2 ISO (PMID:20016786) UniProtKB PMID:20016786 NCBI chrNW_004955478:9,100,863...9,229,448
Ensembl chrNW_004955478:9,100,863...9,231,281
JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 ISO (MGI:MGI:6362140|PMID:31537781) MGI PMID:31537781 MGI:MGI:6362140 NCBI chrNW_004955412:19,670,590...19,672,495 JBrowse link
G Ubxn1 UBX domain protein 1 ISO (PMID:20351172) UniProtKB PMID:20351172 NCBI chrNW_004955599:526,792...529,825
Ensembl chrNW_004955599:526,966...529,735
JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 ISO (PMID:23770237) UniProtKB PMID:23770237 NCBI chrNW_004955406:30,432,652...30,468,741 JBrowse link
G Usp7 ubiquitin specific peptidase 7 ISO (PMID:26678539) UniProtKB PMID:26678539 NCBI chrNW_004955442:9,316,022...9,355,751
Ensembl chrNW_004955442:9,315,225...9,356,393
JBrowse link
G Wac WW domain containing adaptor with coiled-coil ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chrNW_004955462:2,358,842...2,435,644
Ensembl chrNW_004955462:2,358,842...2,435,628
JBrowse link
negative regulation of protein deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 ISO (PMID:15936278) BHF-UCL PMID:15936278 NCBI chrNW_004955453:14,147,286...14,154,396
Ensembl chrNW_004955453:14,148,070...14,154,670
JBrowse link
G Trim21 tripartite motif containing 21 ISO (PMID:16472766) UniProtKB PMID:16472766 NCBI chrNW_004955414:20,066,109...20,077,331
Ensembl chrNW_004955414:20,070,359...20,077,595
JBrowse link
negative regulation of protein K48-linked deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase ISO (PMID:21097510) ParkinsonsUK-UCL PMID:21097510 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885
JBrowse link
G Ubxn1 UBX domain protein 1 ISO (PMID:21135095) ParkinsonsUK-UCL PMID:21135095 NCBI chrNW_004955599:526,792...529,825
Ensembl chrNW_004955599:526,966...529,735
JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp4 acid phosphatase 4 ISO (PMID:15219672) UniProtKB PMID:15219672 NCBI chrNW_004955559:481,953...488,464
Ensembl chrNW_004955559:483,071...486,592
JBrowse link
G Cdh1 cadherin 1 ISO (MGI:MGI:3763814|PMID:17344476) MGI PMID:17344476 MGI:MGI:3763814 NCBI chrNW_004955484:7,782,409...7,861,082
Ensembl chrNW_004955484:7,782,772...7,860,967
JBrowse link
G Chac1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 ISO (PMID:22445366) UniProtKB PMID:22445366 NCBI chrNW_004955416:7,828,917...7,831,368
Ensembl chrNW_004955416:7,828,482...7,832,391
JBrowse link
G Fmr1 FMRP translational regulator 1 ISO Casp3 RGD PMID:22817682 RGD:11566024 NCBI chrNW_004955498:566,741...594,837
Ensembl chrNW_004955498:566,688...595,360
JBrowse link
G Gas1 growth arrest specific 1 ISO (PMID:21357679) UniProtKB PMID:21357679 NCBI chrNW_004955432:727,784...729,096 JBrowse link
G Glg1 golgi glycoprotein 1 ISO (MGI:MGI:4829577|PMID:20530870) MGI PMID:20530870 MGI:MGI:4829577 NCBI chrNW_004955484:2,871,390...2,987,913
Ensembl chrNW_004955484:2,870,872...2,983,467
JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO (MGI:MGI:5468848|PMID:23395675) MGI PMID:23395675 MGI:MGI:5468848 NCBI chrNW_004955470:7,518,565...7,562,219
Ensembl chrNW_004955470:7,518,663...7,559,470
JBrowse link
G Lrrk2 leucine rich repeat kinase 2 ISO (PMID:21370995) ParkinsonsUK-UCL PMID:21370995 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923
JBrowse link
G Mdm2 MDM2 proto-oncogene ISO caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808
JBrowse link
G Ppp1r15a protein phosphatase 1 regulatory subunit 15A ISO Casp3 RGD PMID:21925170 RGD:9999170 NCBI chrNW_004955559:1,750,227...1,753,607 JBrowse link
G Snx12 sorting nexin 12 ISO (PMID:22709416) UniProtKB PMID:22709416 NCBI chrNW_004955475:10,632,938...10,641,452
Ensembl chrNW_004955475:10,474,697...10,641,723
JBrowse link
G Tmem59 transmembrane protein 59 ISO (PMID:20427278) UniProtKB PMID:20427278 NCBI chrNW_004955464:5,193,173...5,222,089
Ensembl chrNW_004955464:5,193,272...5,222,974
JBrowse link
G Tmem98 transmembrane protein 98 ISO (MGI:MGI:6258499|PMID:30249802) UniProt PMID:30249802 MGI:MGI:6258499 NCBI chrNW_004955481:7,788,066...7,797,433
Ensembl chrNW_004955481:7,785,967...7,798,575
JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chrNW_004955455:11,322,812...11,334,786
Ensembl chrNW_004955455:11,324,479...11,334,817
JBrowse link
negative regulation of proteolysis involved in cellular protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efna1 ephrin A1 ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chrNW_004955545:1,610,929...1,617,217
Ensembl chrNW_004955545:1,610,929...1,617,460
JBrowse link
G Epha4 EPH receptor A4 ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chrNW_004955453:12,099,800...12,240,199
Ensembl chrNW_004955453:12,099,757...12,240,199
JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Styx serine/threonine/tyrosine interacting protein ISO (PMID:28007894) UniProtKB PMID:28007894 NCBI chrNW_004955409:10,428,556...10,445,384
Ensembl chrNW_004955409:10,428,556...10,445,880
JBrowse link
negative regulation of serine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102021597 alpha-1-antiproteinase S-like ISO RGD PMID:19240864 RGD:7411612 NCBI chrNW_004955438:17,920,200...17,929,105 JBrowse link
G Spink1 serine peptidase inhibitor Kazal type 1 ISO (MGI:MGI:4442135|PMID:20110462)
(MGI:MGI:5428115|PMID:22228629)
RGD
MGI
PMID:12771515, PMID:20110462, PMID:22228629 MGI:MGI:4442135, MGI:MGI:5428115, RGD:724699 NCBI chrNW_004955415:6,328,672...6,378,611
Ensembl chrNW_004955415:6,371,059...6,378,529
JBrowse link
G Spink2 serine peptidase inhibitor Kazal type 2 ISO (MGI:MGI:5287926|PMID:21705336) MGI PMID:21705336 MGI:MGI:5287926 NCBI chrNW_004955447:14,285,248...14,291,835 JBrowse link
G Spink5 serine peptidase inhibitor Kazal type 5 ISO (MGI:MGI:3770082|PMID:17012259) UniProtKB PMID:17012259 MGI:MGI:3770082 NCBI chrNW_004955415:6,118,616...6,186,632 JBrowse link
G Spink6 serine peptidase inhibitor Kazal type 6 ISO (MGI:MGI:5560845|PMID:24352040) MGI PMID:24352040 MGI:MGI:5560845 NCBI chrNW_004955415:6,041,712...6,053,963
Ensembl chrNW_004955415:6,041,712...6,053,963
JBrowse link
negative regulation of serine-type peptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor Kazal type 5 ISO (MGI:MGI:4440399|PMID:20179351) MGI PMID:20179351 MGI:MGI:4440399 NCBI chrNW_004955415:6,118,616...6,186,632 JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A ISO (MGI:MGI:4461099|PMID:20100865) MGI PMID:20100865 MGI:MGI:4461099 NCBI chrNW_004955437:2,916,598...3,070,771
Ensembl chrNW_004955437:2,916,598...3,070,771
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chrNW_004955597:326,601...397,112 JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chrNW_004955433:15,677,788...15,718,894
Ensembl chrNW_004955433:15,674,116...15,718,894
JBrowse link
G Hfe homeostatic iron regulator ISO (PMID:24904118) BHF-UCL PMID:24904118 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 ISO (PMID:21628596) FlyBase PMID:21628596 NCBI chrNW_004955494:3,365,826...3,554,735
Ensembl chrNW_004955494:3,393,049...3,554,844
JBrowse link
G Pdcl3 phosducin like 3 ISO (PMID:23792958) MGI PMID:23792958 NCBI chrNW_004955470:6,553,450...6,563,814 JBrowse link
G Pml PML nuclear body scaffold ISO (PMID:15195100) UniProtKB PMID:15195100 NCBI chrNW_004955450:3,654,854...3,692,057
Ensembl chrNW_004955450:3,656,498...3,692,406
JBrowse link
G Psen1 presenilin 1 ISO (MGI:MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:MGI:4887523 NCBI chrNW_004955523:2,128,529...2,210,737
Ensembl chrNW_004955523:2,128,529...2,210,737
JBrowse link
G Psen2 presenilin 2 ISO (MGI:MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:MGI:4887523 NCBI chrNW_004955406:5,727,367...5,748,798
Ensembl chrNW_004955406:5,727,367...5,752,234
JBrowse link
G Qrich2 glutamine rich 2 ISO (MGI:MGI:6277293|PMID:30683861)
(PMID:30683861)
UniProt PMID:30683861 MGI:MGI:6277293 NCBI chrNW_004955506:5,990,070...6,015,808 JBrowse link
G Rpl11 ribosomal protein L11 ISO (PMID:18560357) CAFA PMID:18560357 NCBI chrNW_004955452:3,626,609...3,630,911
Ensembl chrNW_004955452:3,626,609...3,633,209
JBrowse link
G Rpl23 ribosomal protein L23 ISO (PMID:15314173) CAFA PMID:15314173 NCBI chrNW_004955451:13,892,880...13,898,079
Ensembl chrNW_004955451:13,892,880...13,898,079
JBrowse link
G Rpl5 ribosomal protein L5 ISO (PMID:18560357) CAFA PMID:18560357 NCBI chrNW_004955423:1,748,809...1,758,622 JBrowse link
G Rps7 ribosomal protein S7 ISO (PMID:17310983) CAFA PMID:17310983 NCBI chrNW_004955487:3,793,168...3,798,007
Ensembl chrNW_004955487:3,792,870...3,798,153
JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat containing alpha ISO (PMID:23129660) UniProtKB PMID:23129660 NCBI chrNW_004955495:5,025,038...5,051,810
Ensembl chrNW_004955495:5,031,229...5,052,389
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO (MGI:MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:MGI:4355593 NCBI chrNW_004955485:7,805,244...7,925,414
Ensembl chrNW_004955485:7,808,131...7,925,677
JBrowse link
G Taf1 TATA-box binding protein associated factor 1 ISO (PMID:17237821) ParkinsonsUK-UCL PMID:17237821 NCBI chrNW_004955475:10,930,175...11,006,876 JBrowse link
G Wnt1 Wnt family member 1 ISO (MGI:MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:MGI:3628833 NCBI chrNW_004955500:7,797,063...7,811,142
Ensembl chrNW_004955500:7,797,060...7,811,167
JBrowse link
negative regulation of ubiquitin-specific protease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase ISO (PMID:21097510) ParkinsonsUK-UCL PMID:21097510 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885
JBrowse link
G Ubxn1 UBX domain protein 1 ISO (PMID:21135095) ParkinsonsUK-UCL PMID:21135095 NCBI chrNW_004955599:526,792...529,825
Ensembl chrNW_004955599:526,966...529,735
JBrowse link
zymogen inhibition term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin, paired basic amino acid cleaving enzyme ISO (PMID:11799113), (PMID:9130696) UniProt PMID:9130696, PMID:11799113 NCBI chrNW_004955416:14,915,031...14,947,634
Ensembl chrNW_004955416:14,936,546...14,949,252
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11889
    metabolic process 7609
      primary metabolic process 6753
        protein metabolic process 3853
          proteolysis 1057
            negative regulation of proteolysis 209
              negative regulation of membrane protein ectodomain proteolysis 5
              negative regulation of peptidase activity + 110
              negative regulation of protein desumoylation 0
              negative regulation of protein deubiquitination + 4
              negative regulation of protein processing + 27
              negative regulation of proteolysis involved in cellular protein catabolic process + 65
Path 2
Term Annotations click to browse term
  biological_process 11889
    metabolic process 7609
      organic substance metabolic process 7318
        macromolecule metabolic process 6345
          protein metabolic process 3853
            cellular protein metabolic process 3512
              regulation of cellular protein metabolic process 2156
                negative regulation of cellular protein metabolic process 829
                  negative regulation of proteolysis 209
                    negative regulation of membrane protein ectodomain proteolysis 5
                    negative regulation of peptidase activity + 110
                    negative regulation of protein desumoylation 0
                    negative regulation of protein deubiquitination + 4
                    negative regulation of protein processing + 27
                    negative regulation of proteolysis involved in cellular protein catabolic process + 65
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.