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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of proteolysis
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Accession:GO:0045861 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Synonyms:exact_synonym: down regulation of proteolysis;   downregulation of proteolysis;   negative regulation of peptidolysis
 narrow_synonym: inhibition of proteolysis


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negative regulation of proteolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G BAG6 BAG cochaperone 6 ISO (MGI:MGI:3774040|PMID:18056262) UniProtKB PMID:18056262 MGI:MGI:3774040 NCBI chr12:1,126,730...1,141,978
Ensembl chr12:1,126,732...1,137,896
JBrowse link
G CDK5 cyclin dependent kinase 5 ISO (PMID:24548080) ParkinsonsUK-UCL PMID:24548080 NCBI chr16:15,105,177...15,113,085
Ensembl chr16:15,101,230...15,109,269
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin IEA Ensembl GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033
JBrowse link
G CSTA cystatin A ISO (PMID:3488317) UniProtKB PMID:3488317 NCBI chr33:25,477,789...25,489,123
Ensembl chr33:25,478,055...25,489,121
JBrowse link
G F2 coagulation factor II, thrombin IEA Ensembl GO_REF:0000107 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459
JBrowse link
G HDAC6 histone deacetylase 6 IEA Ensembl GO_REF:0000107 NCBI chr  X:42,004,268...42,024,726
Ensembl chr  X:42,004,591...42,024,427
JBrowse link
G IDE insulin degrading enzyme ISO inhibits activity of the multicatalytic proteinase complex (proteasome) RGD PMID:9000694 RGD:1627643 NCBI chr28:6,844,480...6,967,713
Ensembl chr28:6,844,055...6,967,713
JBrowse link
G INS insulin ISO (PMID:3553851) BHF-UCL PMID:3553851 NCBI chr18:46,324,047...46,324,933
Ensembl chr18:46,324,041...46,325,122
JBrowse link
G KNG1 kininogen 1 ISO (PMID:3488317) UniProtKB
RGD
PMID:3356189, PMID:3488317 RGD:1600550 NCBI chr34:19,288,629...19,318,096
Ensembl chr34:19,287,109...19,318,081
JBrowse link
G LOC480424 plasma serine protease inhibitor ISO RGD PMID:16088033 RGD:1580291 NCBI chr 8:63,567,060...63,577,015
Ensembl chr 8:63,566,356...63,576,308
JBrowse link
G LOC607874 cystatin-C-like ISO (PMID:3488317) UniProtKB PMID:3488317 NCBI chr23:49,562...53,618 JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:106,332,691...106,339,168
Ensembl chr 1:106,332,798...106,339,135
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 ISO (MGI:MGI:3822255|PMID:18806227) BHF-UCL PMID:18806227 MGI:MGI:3822255 NCBI chr18:42,333,173...42,346,152
Ensembl chr18:42,333,202...42,341,236
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:15161606 RGD:1625251 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970
JBrowse link
G PLAT plasminogen activator, tissue type ISO (PMID:1695900) BHF-UCL PMID:1695900 NCBI chr16:23,469,590...23,496,013 JBrowse link
G RAB23 RAB23, member RAS oncogene family ISO (MGI:MGI:3612806|PMID:16364285) MGI PMID:16364285 MGI:MGI:3612806 NCBI chr12:24,388,530...24,438,956
Ensembl chr12:24,387,643...24,421,869
JBrowse link
G SERPINB10 serpin family B member 10 ISO RGD PMID:11986314 RGD:634009 NCBI chr 1:13,233,715...13,256,289
Ensembl chr 1:13,234,402...13,256,238
JBrowse link
G SERPINE2 serpin family E member 2 ISO (PMID:17379830), (PMID:3997857) BHF-UCL PMID:3997857, PMID:17379830 RGD:8553298 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228
JBrowse link
G SPINK5 serine peptidase inhibitor Kazal type 5 ISO (MGI:MGI:3055648|PMID:15466487) MGI PMID:15466487 MGI:MGI:3055648 NCBI chr 2:42,285,537...42,365,637
Ensembl chr 2:42,285,537...42,365,690
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:17532789 RGD:2290425 NCBI chr 9:2,521,882...2,533,883
Ensembl chr 9:2,521,882...2,533,989
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO RGD PMID:17532789 RGD:2290425 NCBI chr10:30,627,154...30,681,520
Ensembl chr10:30,627,154...30,694,288
JBrowse link
G TM4SF20 transmembrane 4 L six family member 20 IEA Ensembl GO_REF:0000107 NCBI chr25:40,148,578...40,159,975
Ensembl chr25:40,148,570...40,159,959
JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARD8 caspase recruitment domain family, member 8 ISO (PMID:11821383) UniProtKB PMID:11821383 NCBI chr 1:107,994,215...108,025,875 JBrowse link
G CAST calpastatin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:12,920,514...13,031,974
Ensembl chr 3:12,922,453...13,031,959
JBrowse link
G CST7 cystatin F IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr23:1,136,161...1,145,411
Ensembl chr23:1,136,258...1,144,983
JBrowse link
G LOC485601 caspase-14-like ISO (PMID:11821383) UniProtKB PMID:11821383 NCBI chr23:9,047,897...9,068,151 JBrowse link
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2L12 BCL2 like 12 ISO (PMID:22262180) UniProtKB PMID:22262180 NCBI chr 1:106,865,346...106,873,329 JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:29,294,080...29,314,837
Ensembl chr 5:29,294,692...29,312,771
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:29,324,893...29,343,322
Ensembl chr 5:29,325,331...29,337,240
JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr24:46,950,700...46,956,375
Ensembl chr24:46,952,474...46,955,495
JBrowse link
G FCMR Fc fragment of IgM receptor ISO (MGI:MGI:3576402|PMID:15632112) MGI PMID:15632112 MGI:MGI:3576402 NCBI chr 7:6,046,270...6,064,063
Ensembl chr 7:6,048,814...6,064,013
JBrowse link
G HSF4 heat shock transcription factor 4 IEA Ensembl GO_REF:0000107 NCBI chr 5:82,190,996...82,201,224
Ensembl chr 5:82,196,500...82,201,151
Ensembl chr 5:82,196,500...82,201,151
JBrowse link
G XIAP X-linked inhibitor of apoptosis IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582
JBrowse link
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 ISO (MGI:MGI:5811968|PMID:27179792)
(PMID:27179792)
ARUK-UCL PMID:27179792 MGI:MGI:5811968 NCBI chr19:23,503,934...23,534,407
Ensembl chr19:23,375,363...23,534,303
JBrowse link
G SORL1 sortilin related receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:12,493,750...12,650,530
Ensembl chr 5:12,431,377...12,650,784
JBrowse link
negative regulation of cysteine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSN2 casein beta IEA Ensembl GO_REF:0000107 NCBI chr13:59,436,726...59,444,398
Ensembl chr13:59,438,601...59,444,398
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:23690069 RGD:13792722 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
G HTT huntingtin ISO RGD PMID:17124493 RGD:6902918 NCBI chr 3:61,076,934...61,221,462
Ensembl chr 3:61,079,904...61,330,290
JBrowse link
G LOC488622 interferon-activable protein 203 ISO (PMID:22046441) UniProtKB PMID:22046441 NCBI chr38:22,874,345...22,892,362 JBrowse link
G LTF lactotransferrin IEA Ensembl GO_REF:0000107 NCBI chr20:42,231,994...42,263,202
Ensembl chr20:42,231,994...42,263,202
JBrowse link
G PCID2 PCI domain containing 2 IEA Ensembl GO_REF:0000107 NCBI chr22:60,602,440...60,623,811
Ensembl chr22:60,602,888...60,623,719
JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO RGD PMID:15211592 RGD:1625666 NCBI chr26:28,141,076...28,150,600
Ensembl chr26:28,141,076...28,150,598
JBrowse link
G AKT1 AKT serine/threonine kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G AKT2 AKT serine/threonine kinase 2 ISO caspase 3 RGD PMID:18348079 RGD:2313324 NCBI chr 1:113,359,038...113,407,119
Ensembl chr 1:113,359,575...113,407,131
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO (PMID:21215257) UniProtKB PMID:21215257 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720
JBrowse link
G ARRB1 arrestin beta 1 IEA Ensembl GO_REF:0000107 NCBI chr21:23,261,020...23,304,448
Ensembl chr21:23,235,711...23,297,786
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:19171933 RGD:5510006 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454
JBrowse link
G AVP arginine vasopressin IEA Ensembl GO_REF:0000107 NCBI chr24:18,183,057...18,184,827
Ensembl chr24:18,183,057...18,184,883
JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:29,294,080...29,314,837
Ensembl chr 5:29,294,692...29,312,771
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:29,324,893...29,343,322
Ensembl chr 5:29,325,331...29,337,240
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISS UniProtKB GO_REF:0000024 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr24:46,950,700...46,956,375
Ensembl chr24:46,952,474...46,955,495
JBrowse link
G CD27 CD27 molecule IEA GOC GO_REF:0000108 NCBI chr27:38,534,704...38,537,806
Ensembl chr27:38,534,707...38,537,604
JBrowse link
G CD44 CD44 molecule IEA Ensembl GO_REF:0000107 NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107
JBrowse link
G CDKN2D cyclin dependent kinase inhibitor 2D IEA Ensembl GO_REF:0000107 NCBI chr20:50,607,382...50,609,929
Ensembl chr20:50,607,674...50,609,482
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator IEA Ensembl GO_REF:0000107 NCBI chr37:10,268,407...10,307,803
Ensembl chr37:10,268,582...10,345,095
JBrowse link
G CRYAA crystallin alpha A IEA Ensembl GO_REF:0000107 NCBI chr31:37,307,070...37,310,262
Ensembl chr31:37,307,093...37,310,247
JBrowse link
G CRYAB crystallin alpha B IEA Ensembl GO_REF:0000107 NCBI chr 5:21,181,836...21,185,164
Ensembl chr 5:21,179,936...21,360,132
JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO (PMID:16193064) UniProtKB PMID:16193064 NCBI chr24:20,333,593...20,390,341 JBrowse link
G DDX3X DEAD-box helicase 3 X-linked IEA Ensembl GO_REF:0000107 NCBI chr  X:35,759,367...35,789,759
Ensembl chr  X:35,759,416...35,789,774
JBrowse link
G DHCR24 24-dehydrocholesterol reductase IEA Ensembl GO_REF:0000107 NCBI chr 5:54,294,055...54,324,389
Ensembl chr 5:54,294,046...54,321,921
JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 ISO (PMID:10411904) UniProtKB PMID:10411904 NCBI chr 6:36,921,941...36,967,718
Ensembl chr 6:36,917,858...36,967,689
JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 ISO (PMID:11896048) UniProtKB PMID:11896048 NCBI chr16:19,792,957...19,849,299
Ensembl chr16:19,768,639...19,848,139
JBrowse link
G DPEP1 dipeptidase 1 ISS UniProtKB GO_REF:0000024 NCBI chr 5:63,909,034...63,923,309
Ensembl chr 5:63,909,042...63,923,492
JBrowse link
G FABP1 fatty acid binding protein 1 IEA Ensembl GO_REF:0000107 NCBI chr17:38,242,119...38,247,969
Ensembl chr17:38,242,119...38,247,962
JBrowse link
G FNIP1 folliculin interacting protein 1 ISS UniProtKB GO_REF:0000024 NCBI chr11:19,979,294...20,134,341
Ensembl chr11:19,979,163...20,134,229
JBrowse link
G GAS6 growth arrest specific 6 IEA Ensembl GO_REF:0000107 NCBI chr22:60,975,196...61,005,869
Ensembl chr22:60,974,849...61,005,875
JBrowse link
G GPI glucose-6-phosphate isomerase ISO RGD PMID:12615053 RGD:1600634 NCBI chr 1:117,922,380...117,948,325
Ensembl chr 1:117,922,635...117,948,316
JBrowse link
G GPX1 glutathione peroxidase 1 IEA Ensembl GO_REF:0000107 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260
JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 ISO RGD PMID:15102845 RGD:1304324 NCBI chr 2:59,388,492...59,400,028
Ensembl chr 2:59,388,494...59,400,003
JBrowse link
G HGF hepatocyte growth factor IEA Ensembl GO_REF:0000107 NCBI chr18:21,329,688...21,410,257
Ensembl chr18:21,332,817...21,410,263
JBrowse link
G HSP70 heat shock protein 70 ISO (MGI:MGI:2177029|PMID:11879190)
reduced cleavage of Casp8 and Casp9 in brain following hypoxic/ischemic injury
MGI
RGD
PMID:11879190, PMID:16397188 MGI:MGI:2177029, RGD:1626654 NCBI chr12:1,285,282...1,287,670 JBrowse link
G IFI6 interferon alpha inducible protein 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:72,638,657...72,642,648
Ensembl chr 2:72,638,705...72,642,648
JBrowse link
G IGBP1 immunoglobulin binding protein 1 ISO (PMID:17438131) UniProtKB PMID:17438131 NCBI chr  X:54,558,515...54,612,029
Ensembl chr  X:54,547,446...54,613,171
JBrowse link
G IGF1 insulin like growth factor 1 ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794
JBrowse link
G IL24 interleukin 24 ISO (MGI:MGI:3821693|PMID:18708357) MGI PMID:18708357 MGI:MGI:3821693 NCBI chr 7:6,043,249...6,047,097
Ensembl chr 7:6,041,625...6,047,097
JBrowse link
G IL6 interleukin 6 ISO RGD PMID:19061939 RGD:2306937 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G INTS1 integrator complex subunit 1 ISO (MGI:MGI:3722560|PMID:17544522) MGI PMID:17544522 MGI:MGI:3722560 NCBI chr 6:15,453,491...15,483,240
Ensembl chr 6:15,447,391...15,483,239
JBrowse link
G KLF4 Kruppel like factor 4 IEA Ensembl GO_REF:0000107 NCBI chr11:62,881,840...62,886,676
Ensembl chr11:62,882,767...62,928,251
JBrowse link
G LAMP3 lysosomal associated membrane protein 3 ISO (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chr34:16,092,172...16,126,563 JBrowse link
G LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 IEA InterPro GO_REF:0000002 NCBI chr 6:41,591,332...41,595,913 JBrowse link
G LEF1 lymphoid enhancer binding factor 1 IEA Ensembl GO_REF:0000107 NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019
JBrowse link
G LOC100856583 ADP-ribosylation factor-like protein 6-interacting protein 1 ISO (PMID:12754298) UniProtKB PMID:12754298 NCBI chr11:10,744,146...10,744,856 JBrowse link
G LOC102156380 ragulator complex protein LAMTOR5 pseudogene ISO (PMID:12773388) UniProtKB PMID:12773388 NCBI chr 9:53,420,574...53,421,161 JBrowse link
G MAP2K5 mitogen-activated protein kinase kinase 5 ISO PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr30:31,665,032...31,920,792
Ensembl chr30:31,664,564...31,920,751
JBrowse link
G MDM2 MDM2 proto-oncogene ISO caspase-2, caspase-3 RGD PMID:19850968 RGD:2317361 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596
JBrowse link
G MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 IEA Ensembl GO_REF:0000107 NCBI chr12:66,350,459...66,358,391
Ensembl chr12:66,350,427...66,360,615
JBrowse link
G MIR494 microRNA mir-494 ISO (MGI:MGI:5302482|PMID:20837890) MGI PMID:20837890 MGI:MGI:5302482 NCBI chr 8:69,261,385...69,261,465
Ensembl chr 8:69,261,385...69,261,465
JBrowse link
G MRTFA myocardin related transcription factor A IEA Ensembl GO_REF:0000107 NCBI chr10:24,561,161...24,759,586
Ensembl chr10:24,561,161...24,759,081
JBrowse link
G MT3 metallothionein 3 IEA Ensembl GO_REF:0000107 Ensembl chr 2:59,624,849...59,626,424 JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 IEA Ensembl GO_REF:0000107 NCBI chr27:2,947,729...2,965,045
Ensembl chr27:2,891,053...2,955,655
JBrowse link
G PAX2 paired box 2 IEA Ensembl GO_REF:0000107 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094
JBrowse link
G POR cytochrome p450 oxidoreductase ISO caspase-3 RGD PMID:19264869 RGD:2316785 NCBI chr 6:7,247,780...7,316,282
Ensembl chr 6:7,263,574...7,316,297
JBrowse link
G PTGER2 prostaglandin E receptor 2 IMP (PMID:21716255) CAFA PMID:21716255 NCBI chr 8:28,523,318...28,536,936
Ensembl chr 8:28,522,681...28,536,922
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 IEA Ensembl GO_REF:0000107 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G PTMA prothymosin alpha ISO RGD PMID:12522243 RGD:734494 NCBI chr25:43,563,145...43,567,987
Ensembl chr25:43,562,395...43,675,699
JBrowse link
G RAG1 recombination activating 1 IEA Ensembl GO_REF:0000107 NCBI chr18:31,628,231...31,639,980
Ensembl chr18:31,630,737...31,641,660
JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 IEA Ensembl GO_REF:0000107 NCBI chr 2:73,497,128...73,533,853
Ensembl chr 2:73,497,473...73,534,378
JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 IEA Ensembl GO_REF:0000107 NCBI chr  X:15,991,623...16,079,689
Ensembl chr  X:15,998,172...16,074,749
JBrowse link
G SERPINB9 serpin family B member 9 IEA GOC GO_REF:0000108 NCBI chr35:3,186,209...3,200,894
Ensembl chr35:3,190,543...3,199,690
JBrowse link
G SFN stratifin IEA Ensembl GO_REF:0000107 NCBI chr 2:73,268,289...73,269,663
Ensembl chr 2:73,268,791...73,269,537
JBrowse link
G SFRP2 secreted frizzled related protein 2 IEA Ensembl GO_REF:0000107 NCBI chr15:51,541,197...51,548,765
Ensembl chr15:51,540,500...51,548,765
JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 IEA Ensembl GO_REF:0000107 NCBI chr25:20,025,920...20,208,470
Ensembl chr25:20,015,915...20,205,946
JBrowse link
G SIAH2 siah E3 ubiquitin protein ligase 2 IEA Ensembl GO_REF:0000107 NCBI chr23:45,366,343...45,418,960
Ensembl chr23:45,341,199...45,385,546
JBrowse link
G SNCA synuclein alpha IEA Ensembl GO_REF:0000107 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077
JBrowse link
G THBS1 thrombospondin 1 IEA Ensembl GO_REF:0000107 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915
JBrowse link
G TNF tumor necrosis factor IEA Ensembl GO_REF:0000107 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TNFAIP8 TNF alpha induced protein 8 IEA GOC GO_REF:0000108 NCBI chr11:8,624,106...8,685,389
Ensembl chr11:8,660,557...8,684,374
JBrowse link
G TNFSF14 TNF superfamily member 14 IEA GOC GO_REF:0000108 NCBI chr20:53,604,101...53,607,522
Ensembl chr20:53,603,709...53,607,522
JBrowse link
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 ISO (PMID:15735003) BHF-UCL PMID:15735003 NCBI chr26:16,349,513...16,352,805
Ensembl chr26:16,351,044...16,352,773
JBrowse link
G USP47 ubiquitin specific peptidase 47 IEA Ensembl GO_REF:0000107 NCBI chr21:34,917,664...35,027,969
Ensembl chr21:34,911,269...35,026,790
JBrowse link
G VEGFA vascular endothelial growth factor A ISO (PMID:18386220) UniProtKB PMID:18386220 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link
G VIL1 villin 1 IEA GOC GO_REF:0000108 NCBI chr37:25,065,887...25,090,238
Ensembl chr37:25,065,180...25,090,705
JBrowse link
G WNT9A Wnt family member 9A IEA Ensembl GO_REF:0000107 NCBI chr14:946,843...959,289
Ensembl chr14:953,244...959,295
JBrowse link
G XIAP X-linked inhibitor of apoptosis IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582
JBrowse link
G ZC3H7B zinc finger CCCH-type containing 7B ISO cardiac myocytes RGD PMID:22562121 RGD:7327216 NCBI chr10:23,882,379...23,944,850
Ensembl chr10:23,884,981...23,920,131
JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAAP1 caspase activity and apoptosis inhibitor 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:45,063,524...45,112,437
Ensembl chr11:45,064,472...45,109,672
JBrowse link
G MMP9 matrix metallopeptidase 9 IEA Ensembl GO_REF:0000107 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293
JBrowse link
G NLE1 notchless homolog 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:38,222,083...38,230,819
Ensembl chr 9:38,222,051...38,365,621
JBrowse link
G PARK7 Parkinsonism associated deglycase ISO (PMID:21785459) ParkinsonsUK-UCL PMID:21785459 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303
JBrowse link
G PIH1D1 PIH1 domain containing 1 ISO (PMID:21078300) UniProtKB PMID:21078300 NCBI chr 1:107,045,466...107,051,281
Ensembl chr 1:107,045,697...107,051,236
JBrowse link
G PLAUR plasminogen activator, urokinase receptor IEA Ensembl GO_REF:0000107 NCBI chr 1:111,476,804...111,490,876
Ensembl chr 1:111,476,893...111,490,880
JBrowse link
G RAD51D RAD51 paralog D IEA Ensembl GO_REF:0000107 NCBI chr 9:38,242,178...38,259,788
Ensembl chr 9:38,222,051...38,365,621
JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase IEA Ensembl GO_REF:0000107 NCBI chr 9:38,271,419...38,346,103
Ensembl chr 9:38,222,051...38,365,621
JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLE1 notchless homolog 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:38,222,083...38,230,819
Ensembl chr 9:38,222,051...38,365,621
JBrowse link
G PAK2 p21 (RAC1) activated kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr33:29,774,645...29,863,661
Ensembl chr33:29,774,593...29,987,478
JBrowse link
G RAD51D RAD51 paralog D IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:38,242,178...38,259,788
Ensembl chr 9:38,222,051...38,365,621
JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:38,271,419...38,346,103
Ensembl chr 9:38,222,051...38,365,621
JBrowse link
G RNF34 ring finger protein 34 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:7,746,460...7,767,967
Ensembl chr26:7,744,924...7,767,892
JBrowse link
negative regulation of endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2ML1 alpha-2-macroglobulin like 1 IEA GOC GO_REF:0000108 NCBI chr27:36,844,292...36,882,274
Ensembl chr27:36,844,572...36,883,887
JBrowse link
G AGT angiotensinogen IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880
JBrowse link
G AHSG alpha 2-HS glycoprotein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr34:19,221,034...19,228,866
Ensembl chr34:19,221,107...19,228,716
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor IEA GOC GO_REF:0000108 NCBI chr11:68,338,644...68,353,366
Ensembl chr11:68,338,389...68,351,994
JBrowse link
G ANXA2 annexin A2 IEA GOC GO_REF:0000108 NCBI chr30:25,176,845...25,210,244
Ensembl chr30:25,115,842...25,218,281
JBrowse link
G APLP2 amyloid beta precursor like protein 2 IEA GOC GO_REF:0000108 NCBI chr 5:4,704,155...4,786,011
Ensembl chr 5:4,705,491...4,786,079
JBrowse link
G APP amyloid beta precursor protein IEA GOC GO_REF:0000108 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
G BIRC6 baculoviral IAP repeat containing 6 IEA GOC GO_REF:0000108 NCBI chr17:25,618,262...25,847,920
Ensembl chr17:25,617,892...25,847,202
JBrowse link
G BST2 bone marrow stromal cell antigen 2 IEA GOC GO_REF:0000108 NCBI chr20:45,383,757...45,387,420
Ensembl chr20:45,383,915...45,387,178
JBrowse link
G C3 complement C3 IEA GOC GO_REF:0000108 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G C5 complement C5 IEA GOC GO_REF:0000108 NCBI chr11:73,953,727...74,029,919
Ensembl chr11:73,953,727...74,029,851
JBrowse link
G CD109 CD109 molecule IEA GOC GO_REF:0000108 NCBI chr12:35,712,589...35,839,153
Ensembl chr12:35,712,271...35,839,044
JBrowse link
G CE10 CE10 protein IEA GOC GO_REF:0000108 NCBI chr24:32,847,081...32,848,913
Ensembl chr24:32,847,081...32,848,919
JBrowse link
G COL28A1 collagen type XXVIII alpha 1 chain IEA GOC GO_REF:0000108 NCBI chr14:22,991,469...23,153,333
Ensembl chr14:22,993,286...23,153,305
JBrowse link
G COL6A3 collagen type VI alpha 3 chain IEA GOC GO_REF:0000108 NCBI chr25:47,971,439...48,052,673
Ensembl chr25:47,971,315...48,052,402
JBrowse link
G COL7A1 collagen type VII alpha 1 chain IEA GOC GO_REF:0000108 NCBI chr20:40,519,121...40,550,305
Ensembl chr20:40,519,378...40,552,935
JBrowse link
G CPAMD8 C3 and PZP like alpha-2-macroglobulin domain containing 8 IEA GOC GO_REF:0000108 NCBI chr20:45,659,795...45,737,492
Ensembl chr20:45,653,620...45,736,931
JBrowse link
G CRB2 crumbs cell polarity complex component 2 IEA Ensembl GO_REF:0000107 NCBI chr 9:59,427,661...59,450,436
Ensembl chr 9:59,427,569...59,450,434
JBrowse link
G CRIM1 cysteine rich transmembrane BMP regulator 1 IEA GOC GO_REF:0000108 NCBI chr17:28,857,702...29,042,399
Ensembl chr17:28,857,696...29,040,002
JBrowse link
G CST11 cystatin 11 IEA GOC GO_REF:0000108 NCBI chr24:181,410...184,213
Ensembl chr24:180,692...184,323
JBrowse link
G CST6 cystatin E/M IEA GOC GO_REF:0000108 NCBI chr18:51,263,161...51,264,816
Ensembl chr18:51,263,178...51,264,780
JBrowse link
G CST8 cystatin 8 IEA GOC GO_REF:0000108 NCBI chr24:110,591...119,626
Ensembl chr24:110,702...119,172
JBrowse link
G CSTA cystatin A IEA GOC GO_REF:0000108 NCBI chr33:25,477,789...25,489,123
Ensembl chr33:25,478,055...25,489,121
JBrowse link
G CSTB cystatin B IEA GOC GO_REF:0000108 Ensembl chr31:37,717,955...37,719,546 JBrowse link
G CSTL1 cystatin like 1 IEA GOC GO_REF:0000108 NCBI chr24:197,438...202,306
Ensembl chr24:197,472...202,316
JBrowse link
G FETUB fetuin B IEA
IBA
(PMID:21873635) GOC
GO_Central
PMID:21873635 GO_REF:0000108 NCBI chr34:19,259,362...19,273,030
Ensembl chr34:19,259,357...19,273,030
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme IEA GOC GO_REF:0000108 NCBI chr 3:53,357,491...53,368,285
Ensembl chr 3:53,358,045...53,365,423
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO (PMID:22832495) UniProtKB PMID:22832495 NCBI chr27:38,468,889...38,472,653
Ensembl chr27:38,468,889...38,472,385
JBrowse link
G HRG histidine rich glycoprotein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr34:19,276,487...19,286,540
Ensembl chr34:19,276,549...19,286,537
JBrowse link
G ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 IEA GOC GO_REF:0000108 NCBI chr20:37,038,070...37,051,866
Ensembl chr20:37,038,070...37,052,675
JBrowse link
G ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 IEA GOC GO_REF:0000108 NCBI chr 2:28,367,842...28,403,610
Ensembl chr 2:28,367,908...28,403,667
JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 IEA GOC GO_REF:0000108
G ITIH5 inter-alpha-trypsin inhibitor heavy chain 5 IEA GOC GO_REF:0000108 NCBI chr 2:28,437,907...28,507,008
Ensembl chr 2:28,441,056...28,506,966
JBrowse link
G KNG1 kininogen 1 IEA GOC GO_REF:0000108 NCBI chr34:19,288,629...19,318,096
Ensembl chr34:19,287,109...19,318,081
JBrowse link
G LOC100685761 WAP four-disulfide core domain protein 10A-like IEA GOC GO_REF:0000108 NCBI chr24:32,909,505...32,910,890
Ensembl chr24:32,909,505...32,910,860
JBrowse link
G LOC100685852 protein WFDC9-like IEA GOC GO_REF:0000108 NCBI chr24:32,922,063...32,929,964
Ensembl chr24:32,926,995...32,929,081
JBrowse link
G LOC102151893 uncharacterized LOC102151893 IEA GOC GO_REF:0000108 NCBI chr 9:37,618,049...37,622,296 JBrowse link
G LOC102152702 WAP four-disulfide core domain protein 6A-like IEA GOC GO_REF:0000108 NCBI chr24:32,799,699...32,804,545 JBrowse link
G LOC102156375 probable cystatin-15 IEA GOC GO_REF:0000108 NCBI chr24:144,115...148,182 JBrowse link
G LOC111092171 double-headed protease inhibitor, submandibular gland IEA GOC GO_REF:0000108 NCBI chr 2:42,375,657...42,380,862 JBrowse link
G LOC477699 alpha-2-macroglobulin IEA GOC GO_REF:0000108 NCBI chr27:36,654,328...36,695,775 JBrowse link
G LOC480424 plasma serine protease inhibitor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:63,567,060...63,577,015
Ensembl chr 8:63,566,356...63,576,308
JBrowse link
G LOC480425 alpha-1-antichymotrypsin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:63,588,188...63,596,955
Ensembl chr 8:63,587,891...63,596,954
JBrowse link
G LOC481722 complement C4-A IEA GOC GO_REF:0000108 NCBI chr12:1,433,185...1,448,056 JBrowse link
G LOC484960 complement C3 IEA GOC GO_REF:0000108 NCBI chr20:50,993,122...51,019,645 JBrowse link
G LOC485559 cystatin 9 (testatin) IEA GOC GO_REF:0000108 NCBI chr23:1,913...5,329 JBrowse link
G LOC491368 inter-alpha-trypsin inhibitor heavy chain H3 IEA GOC GO_REF:0000108
G LOC606793 cystatin-13-like IEA GOC GO_REF:0000108 NCBI chr24:71,236...93,269 JBrowse link
G LOC607874 cystatin-C-like IEA GOC GO_REF:0000108 NCBI chr23:49,562...53,618 JBrowse link
G LOC610614 collagen alpha-4(VI) chain-like IEA GOC GO_REF:0000108 NCBI chr23:27,419,042...27,530,981 JBrowse link
G LOC611455 ovostatin homolog 2-like IEA GOC GO_REF:0000108 NCBI chr27:36,412,017...36,464,973 JBrowse link
G LOC611458 pregnancy zone protein-like IEA GOC GO_REF:0000108 NCBI chr27:36,527,426...36,577,684 JBrowse link
G LXN latexin IEA GOC GO_REF:0000108 NCBI chr23:51,962,877...51,968,447
Ensembl chr23:51,962,873...51,969,172
JBrowse link
G NGF nerve growth factor IEA GOC GO_REF:0000108 NCBI chr17:52,900,647...52,901,607
Ensembl chr17:52,900,647...52,901,607
JBrowse link
G PAPLN papilin, proteoglycan like sulfated glycoprotein IEA GOC GO_REF:0000108 NCBI chr 8:46,587,197...46,620,381
Ensembl chr 8:46,592,854...46,618,612
JBrowse link
G PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor IEA InterPro GO_REF:0000002 NCBI chr  X:42,030,708...42,036,363
Ensembl chr  X:41,962,524...42,036,586
JBrowse link
G PEBP1 phosphatidylethanolamine binding protein 1 IEA GOC GO_REF:0000108 NCBI chr26:14,522,124...14,526,370
Ensembl chr26:14,500,074...14,529,354
JBrowse link
G PI3 peptidase inhibitor 3 IEA GOC GO_REF:0000108 NCBI chr24:32,504,697...32,506,214
Ensembl chr24:32,504,675...32,506,214
JBrowse link
G PRNP prion protein IEA GOC GO_REF:0000108 NCBI chr24:16,845,224...16,862,319
Ensembl chr24:16,846,207...16,859,815
JBrowse link
G PTTG1 PTTG1 regulator of sister chromatid separation, securin IEA GOC GO_REF:0000108 NCBI chr 4:50,301,868...50,309,636 JBrowse link
G RARRES1 retinoic acid receptor responder 1 IEA GOC GO_REF:0000108 NCBI chr23:51,992,368...52,019,242
Ensembl chr23:51,992,606...52,019,311
JBrowse link
G RECK reversion inducing cysteine rich protein with kazal motifs IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:52,519,303...52,607,753
Ensembl chr11:52,519,317...52,607,217
JBrowse link
G RENBP renin binding protein ISO RGD PMID:11926999 RGD:727355 NCBI chr  X:121,782,411...121,788,928
Ensembl chr  X:121,727,573...121,788,860
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 IEA GOC GO_REF:0000108 NCBI chr 7:66,862,614...67,001,538
Ensembl chr 7:66,862,608...67,142,853
JBrowse link
G SERPINA1 serpin family A member 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:63,388,498...63,400,377
Ensembl chr 8:63,376,945...63,398,435
JBrowse link
G SERPINA11 serpin family A member 11 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:63,436,710...63,453,354
Ensembl chr 8:63,323,933...63,453,708
JBrowse link
G SERPINA12 serpin family A member 12 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:63,497,542...63,511,701
Ensembl chr 8:63,497,849...63,512,171
JBrowse link
G SERPINA14 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 14 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:63,457,140...63,465,073 JBrowse link
G SERPINA4 serpin family A member 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:63,552,033...63,560,667
Ensembl chr 8:63,552,107...63,560,667
JBrowse link
G SERPINA6 serpin family A member 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:63,323,896...63,341,829
Ensembl chr 8:63,323,933...63,453,708
JBrowse link
G SERPINA7 serpin family A member 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:79,571,169...79,589,199
Ensembl chr  X:79,571,169...79,576,759
JBrowse link
G SERPINA9 serpin family A member 9 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:63,473,622...63,487,720
Ensembl chr 8:63,473,687...63,488,556
JBrowse link
G SERPINB1 serpin family B member 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr35:3,147,140...3,151,747
Ensembl chr35:3,147,170...3,153,915
JBrowse link
G SERPINB10 serpin family B member 10 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:13,233,715...13,256,289
Ensembl chr 1:13,234,402...13,256,238
JBrowse link
G SERPINB11 serpin family B member 11 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:13,395,127...13,486,974
Ensembl chr 1:13,410,079...13,487,008
JBrowse link
G SERPINB12 serpin family B member 12 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:13,516,993...13,539,834
Ensembl chr 1:13,518,850...13,539,956
JBrowse link
G SERPINB13 serpin family B member 13 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:13,492,998...13,505,716
Ensembl chr 1:13,493,301...13,505,001
JBrowse link
G SERPINB2 serpin family B member 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:13,260,288...13,276,727
Ensembl chr 1:13,260,387...13,272,980
JBrowse link
G SERPINB5 serpin family B member 5 IBA
IEA
(PMID:21873635) GO_Central
GOC
PMID:21873635 GO_REF:0000108 NCBI chr 1:13,566,982...13,638,839
Ensembl chr 1:13,568,376...13,638,781
JBrowse link
G SERPINB6 serpin family B member 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr35:3,234,694...3,245,726
Ensembl chr35:3,234,697...3,262,829
JBrowse link
G SERPINB7 serpin family B member 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:13,336,067...13,392,674
Ensembl chr 1:13,336,837...13,358,125
JBrowse link
G SERPINB8 serpin family B member 8 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:13,213,506...13,223,489
Ensembl chr 1:13,200,602...13,222,943
JBrowse link
G SERPINB9 serpin family B member 9 IEA
IBA
(PMID:21873635) GOC
GO_Central
PMID:21873635 GO_REF:0000108 NCBI chr35:3,186,209...3,200,894
Ensembl chr35:3,190,543...3,199,690
JBrowse link
G SERPINC1 serpin family C member 1 IBA
IEA
(PMID:21873635) GO_Central
GOC
PMID:21873635 GO_REF:0000108 NCBI chr 7:25,322,668...25,333,022
Ensembl chr 7:25,316,129...25,332,987
JBrowse link
G SERPIND1 serpin family D member 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:30,686,074...30,697,437
Ensembl chr26:30,686,663...30,693,848
JBrowse link
G SERPINE1 serpin family E member 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301
JBrowse link
G SERPINE2 serpin family E member 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228
JBrowse link
G SERPINE3 serpin family E member 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:637,600...666,028
Ensembl chr22:636,466...663,695
JBrowse link
G SERPINF1 serpin family F member 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:45,891,368...45,902,768
Ensembl chr 9:45,891,410...45,902,765
JBrowse link
G SERPINF2 serpin family F member 2 IBA
IEA
(PMID:21873635) GO_Central
GOC
PMID:21873635 GO_REF:0000108 NCBI chr 9:45,876,076...45,883,777
Ensembl chr 9:45,877,495...45,883,036
JBrowse link
G SERPING1 serpin family G member 1 IBA
IEA
(PMID:21873635) GO_Central
GOC
PMID:21873635 GO_REF:0000108 NCBI chr18:38,570,354...38,580,751
Ensembl chr18:38,570,607...38,581,665
JBrowse link
G SERPINH1 serpin family H member 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr21:23,032,761...23,041,649
Ensembl chr21:23,032,767...23,041,625
JBrowse link
G SERPINI1 serpin family I member 1 IBA
IEA
(PMID:21873635) GO_Central
GOC
PMID:21873635 GO_REF:0000108 NCBI chr34:32,553,876...32,624,708
Ensembl chr34:32,553,902...32,624,526
JBrowse link
G SERPINI2 serpin family I member 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr34:32,326,640...32,359,550
Ensembl chr34:32,321,023...32,359,291
JBrowse link
G SLPI secretory leukocyte peptidase inhibitor IEA GOC GO_REF:0000108 NCBI chr24:32,566,030...32,568,406
Ensembl chr24:32,566,026...32,568,420
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 IEA GOC GO_REF:0000108 NCBI chr 2:42,112,015...42,120,738
Ensembl chr 2:42,112,016...42,120,706
JBrowse link
G SPINK2 serine peptidase inhibitor, Kazal type 2 IEA GOC GO_REF:0000108 NCBI chr13:48,952,869...48,964,862
Ensembl chr13:48,944,135...48,964,831
JBrowse link
G SPINK6 serine peptidase inhibitor Kazal type 6 IEA GOC GO_REF:0000108 NCBI chr 2:42,409,038...42,425,540
Ensembl chr 2:42,415,406...42,425,535
JBrowse link
G SPINK9 serine peptidase inhibitor Kazal type 9 IEA GOC GO_REF:0000108 Ensembl chr 4:60,454,570...60,459,650 JBrowse link
G SPINT1 serine peptidase inhibitor, Kunitz type 1 IEA GOC GO_REF:0000108 NCBI chr30:7,976,094...7,989,019
Ensembl chr30:7,975,235...7,988,339
JBrowse link
G SPINT2 serine peptidase inhibitor, Kunitz type 2 IEA GOC GO_REF:0000108 NCBI chr 1:114,699,050...114,727,802
Ensembl chr 1:114,699,241...114,727,763
JBrowse link
G SPINT3 serine peptidase inhibitor, Kunitz type 3 IEA GOC GO_REF:0000108 NCBI chr24:32,721,798...32,724,433
Ensembl chr24:32,721,798...32,724,408
JBrowse link
G SPINT4 serine peptidase inhibitor, Kunitz type 4 IEA GOC GO_REF:0000108 NCBI chr24:33,035,050...33,037,192
Ensembl chr24:33,034,698...33,036,124
JBrowse link
G SPOCK1 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 IEA Ensembl GO_REF:0000107 NCBI chr11:24,733,290...25,013,400
Ensembl chr11:24,733,603...25,007,376
JBrowse link
G SPOCK3 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 ISO (PMID:11751414) UniProtKB PMID:11751414 NCBI chr15:62,395,713...62,661,308
Ensembl chr15:62,395,707...62,661,312
JBrowse link
G TFPI tissue factor pathway inhibitor IEA GOC GO_REF:0000108 NCBI chr36:29,457,131...29,546,455
Ensembl chr36:29,459,371...29,511,310
JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 IEA GOC GO_REF:0000108 NCBI chr14:19,399,259...19,403,890
Ensembl chr14:19,399,720...19,403,708
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISS
IEA
IBA
(PMID:21873635) UniProtKB
GOC
GO_Central
PMID:21873635 GO_REF:0000024, GO_REF:0000108 NCBI chr  X:41,201,623...41,205,314
Ensembl chr  X:41,201,638...41,205,310
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 9:2,521,882...2,533,883
Ensembl chr 9:2,521,882...2,533,989
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 IEA GOC GO_REF:0000108 NCBI chr10:30,627,154...30,681,520
Ensembl chr10:30,627,154...30,694,288
JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:6,399,522...6,405,089
Ensembl chr20:6,399,522...6,405,089
JBrowse link
G UBE2O ubiquitin conjugating enzyme E2 O IEA GOC GO_REF:0000108 NCBI chr 9:4,294,192...4,310,971
Ensembl chr 9:4,254,649...4,310,589
JBrowse link
G UBE2Z ubiquitin conjugating enzyme E2 Z IEA GOC GO_REF:0000108 NCBI chr 9:25,134,715...25,150,694
Ensembl chr 9:25,139,253...25,149,027
JBrowse link
G USP14 ubiquitin specific peptidase 14 IEA GOC GO_REF:0000108 NCBI chr 7:67,035,774...67,080,082
Ensembl chr 7:67,035,843...67,079,465
JBrowse link
G VTN vitronectin IEA Ensembl GO_REF:0000107 NCBI chr 9:42,617,860...42,620,825
Ensembl chr 9:42,614,941...42,630,864
JBrowse link
G WFDC11 WAP four-disulfide core domain 11 IEA GOC GO_REF:0000108 Ensembl chr24:32,979,301...32,981,045 JBrowse link
G WFDC13 WAP four-disulfide core domain 13 IEA GOC GO_REF:0000108 NCBI chr24:33,011,202...33,029,260
Ensembl chr24:33,011,272...33,019,696
JBrowse link
G WFDC2 WAP four-disulfide core domain 2 IEA GOC GO_REF:0000108 NCBI chr24:32,759,763...32,764,620
Ensembl chr24:32,759,696...32,764,620
JBrowse link
G WFDC3 WAP four-disulfide core domain 3 IEA GOC GO_REF:0000108 NCBI chr24:33,087,487...33,102,721
Ensembl chr24:33,087,547...33,102,872
JBrowse link
G WFDC5 WAP four-disulfide core domain 5 IEA GOC GO_REF:0000108 NCBI chr24:32,487,339...32,492,660
Ensembl chr24:32,487,348...32,510,990
JBrowse link
G WFDC8 WAP four-disulfide core domain 8 IEA GOC GO_REF:0000108 NCBI chr24:32,813,432...32,829,108
Ensembl chr24:32,814,662...32,823,340
JBrowse link
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 IEA GOC GO_REF:0000108 NCBI chr 6:39,934,105...39,937,666
Ensembl chr 6:39,934,068...39,936,628
JBrowse link
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 IEA GOC GO_REF:0000108 NCBI chr 9:26,711,470...26,717,625
Ensembl chr 9:26,711,959...26,716,348
JBrowse link
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SGTA small glutamine rich tetratricopeptide repeat containing alpha IEA Ensembl GO_REF:0000107 NCBI chr20:56,432,688...56,451,438
Ensembl chr20:56,441,724...56,450,215
JBrowse link
G SVIP small VCP interacting protein ISO (PMID:17872946) UniProtKB PMID:17872946 NCBI chr21:44,408,467...44,418,160
Ensembl chr21:44,408,474...44,415,739
JBrowse link
G USP14 ubiquitin specific peptidase 14 IEA Ensembl GO_REF:0000107 NCBI chr 7:67,035,774...67,080,082
Ensembl chr 7:67,035,843...67,079,465
JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP11 aquaporin 11 IEA Ensembl GO_REF:0000107 NCBI chr21:21,170,760...21,185,709
Ensembl chr21:21,171,008...21,185,429
JBrowse link
G UBXN1 UBX domain protein 1 IEA Ensembl GO_REF:0000107 NCBI chr18:53,977,937...53,982,108
Ensembl chr18:53,978,062...53,982,111
JBrowse link
G USP25 ubiquitin specific peptidase 25 IEA Ensembl GO_REF:0000107 NCBI chr31:12,555,614...12,692,765
Ensembl chr31:12,555,595...12,691,694
JBrowse link
negative regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 ISS
IEA
UniProtKB
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G LRIG2 leucine rich repeats and immunoglobulin like domains 2 IEA Ensembl GO_REF:0000107 NCBI chr17:62,487,802...62,548,883
Ensembl chr17:62,489,462...62,548,666
JBrowse link
G PTPN3 protein tyrosine phosphatase non-receptor type 3 IEA Ensembl GO_REF:0000107 NCBI chr11:64,486,293...64,595,416
Ensembl chr11:64,489,446...64,630,004
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:41,201,623...41,205,314
Ensembl chr  X:41,201,638...41,205,310
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:2,521,882...2,533,883
Ensembl chr 9:2,521,882...2,533,989
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO (PMID:18383040) BHF-UCL PMID:18383040 NCBI chr10:30,627,154...30,681,520
Ensembl chr10:30,627,154...30,694,288
JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:6,399,522...6,405,089
Ensembl chr20:6,399,522...6,405,089
JBrowse link
negative regulation of metalloendopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RECK reversion inducing cysteine rich protein with kazal motifs IBA
IEA
(PMID:21873635) GO_Central
Ensembl
InterPro
PMID:21873635 GO_REF:0000002, GO_REF:0000107 NCBI chr11:52,519,303...52,607,753
Ensembl chr11:52,519,317...52,607,217
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO (MGI:MGI:5659805|PMID:24812324) BHF-UCL PMID:24812324 MGI:MGI:5659805 NCBI chr10:30,627,154...30,681,520
Ensembl chr10:30,627,154...30,694,288
JBrowse link
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PICALM phosphatidylinositol binding clathrin assembly protein IEA Ensembl GO_REF:0000107 NCBI chr21:13,437,819...13,540,167
Ensembl chr21:13,437,925...13,539,616
JBrowse link
G SORL1 sortilin related receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:12,493,750...12,650,530
Ensembl chr 5:12,431,377...12,650,784
JBrowse link
negative regulation of metallopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO (PMID:9573338) UniProtKB PMID:9573338 NCBI chr  X:41,201,623...41,205,314
Ensembl chr  X:41,201,638...41,205,310
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 IEA Ensembl GO_REF:0000107 NCBI chr 9:2,521,882...2,533,883
Ensembl chr 9:2,521,882...2,533,989
JBrowse link
negative regulation of peptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANOS1 anosmin 1 IEA GOC GO_REF:0000108 NCBI chr  X:5,413,958...5,601,663
Ensembl chr  X:5,415,575...5,762,656
JBrowse link
G CAST calpastatin ISO (MGI:MGI:5295525|PMID:21849499) MGI PMID:21849499 MGI:MGI:5295525 NCBI chr 3:12,920,514...13,031,974
Ensembl chr 3:12,922,453...13,031,959
JBrowse link
G CST7 cystatin F ISO (PMID:15752368), (PMID:18256700), (PMID:22365146)
(MGI:MGI:6294189|PMID:18256700)
ARUK-UCL PMID:15752368, PMID:18256700, PMID:22365146 MGI:MGI:6294189 NCBI chr23:1,136,161...1,145,411
Ensembl chr23:1,136,258...1,144,983
JBrowse link
G CSTA cystatin A ISO (PMID:6203523) BHF-UCL PMID:6203523 NCBI chr33:25,477,789...25,489,123
Ensembl chr33:25,478,055...25,489,121
JBrowse link
G ECM1 extracellular matrix protein 1 IEA Ensembl GO_REF:0000107 NCBI chr17:59,696,125...59,701,990
Ensembl chr17:59,696,477...59,701,744
JBrowse link
G GPC3 glypican 3 IEA GOC GO_REF:0000108 NCBI chr  X:104,313,426...104,751,215
Ensembl chr  X:104,313,591...104,751,756
JBrowse link
G LOC102152702 WAP four-disulfide core domain protein 6A-like IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr24:32,799,699...32,804,545 JBrowse link
G LOC483954 serpin B3 ISO (PMID:12949073) UniProtKB PMID:12949073 NCBI chr 1:13,471,412...13,472,089 JBrowse link
G LOC607874 cystatin-C-like ISO (PMID:18256700), (PMID:6203523), (PMID:7890620) ARUK-UCL PMID:6203523, PMID:7890620, PMID:18256700 NCBI chr23:49,562...53,618 JBrowse link
G SERPINE2 serpin family E member 2 ISO (MGI:MGI:3521551|PMID:15509762), (MGI:MGI:3810206|PMID:18398001) MGI PMID:15509762, PMID:18398001 MGI:MGI:3521551, MGI:MGI:3810206 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 ISO (MGI:MGI:72783|PMID:3428272) MGI PMID:3428272 MGI:MGI:72783 NCBI chr 2:42,112,015...42,120,738
Ensembl chr 2:42,112,016...42,120,706
JBrowse link
G UMODL1 uromodulin like 1 IEA GOC GO_REF:0000108 NCBI chr31:36,452,008...36,510,649
Ensembl chr31:36,449,660...36,510,683
JBrowse link
G WFDC1 WAP four-disulfide core domain 1 IEA GOC GO_REF:0000108 NCBI chr 5:68,067,894...68,095,749
Ensembl chr 5:68,067,885...68,096,067
JBrowse link
G WFDC10B WAP four-disulfide core domain 10B IEA GOC GO_REF:0000108 NCBI chr24:33,004,209...33,006,293
Ensembl chr24:33,004,365...33,006,332
JBrowse link
G WFDC3 WAP four-disulfide core domain 3 IEA GOC GO_REF:0000108 NCBI chr24:33,087,487...33,102,721
Ensembl chr24:33,087,547...33,102,872
JBrowse link
G WFDC5 WAP four-disulfide core domain 5 IEA GOC GO_REF:0000108 NCBI chr24:32,487,339...32,492,660
Ensembl chr24:32,487,348...32,510,990
JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPB2 carboxypeptidase B2 ISO RGD PMID:23369837 RGD:7243115 NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170
JBrowse link
G CTSZ cathepsin Z IEA Ensembl GO_REF:0000107 NCBI chr24:43,743,291...43,750,154
Ensembl chr24:43,743,294...43,754,424
JBrowse link
G SERPINE1 serpin family E member 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301
JBrowse link
G SERPINE2 serpin family E member 2 IEA Ensembl GO_REF:0000107 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228
JBrowse link
G SERPINF2 serpin family F member 2 IEA Ensembl GO_REF:0000107 NCBI chr 9:45,876,076...45,883,777
Ensembl chr 9:45,877,495...45,883,036
JBrowse link
G THBS1 thrombospondin 1 IEA Ensembl GO_REF:0000107 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915
JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase IEA Ensembl GO_REF:0000107 NCBI chr11:67,736,643...67,752,399
Ensembl chr11:67,741,390...67,752,321
JBrowse link
G F8A1 coagulation factor VIII associated 1 ISO (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:122,914,362...122,916,199 JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:75,230,214...75,240,724
Ensembl chr 5:75,230,243...75,240,730
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO PMID:17517623
(MGI:MGI:6148636|PMID:17517623)
ARUK-UCL PMID:17517623 MGI:MGI:6148636, RGD:13514081 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940
JBrowse link
G LAMP3 lysosomal associated membrane protein 3 ISO (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chr34:16,092,172...16,126,563 JBrowse link
G LOC484316 protein kinase C gamma type IEA Ensembl GO_REF:0000107 NCBI chr 1:103,495,013...103,512,465 JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 IEA Ensembl GO_REF:0000107 NCBI chr36:5,481,449...5,533,139
Ensembl chr36:5,481,456...5,531,957
JBrowse link
G OPHN1 oligophrenin 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:52,418,390...52,983,155
Ensembl chr  X:52,455,373...52,982,244
JBrowse link
G PRKCG protein kinase C gamma IEA Ensembl GO_REF:0000107 NCBI chr 1:103,295,110...103,312,562 JBrowse link
G PSME3IP1 proteasome activator subunit 3 interacting protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:59,185,238...59,220,515
Ensembl chr 2:59,186,349...59,220,515
JBrowse link
G PSMF1 proteasome inhibitor subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr24:19,817,104...19,863,632
Ensembl chr24:19,819,055...19,859,586
JBrowse link
G SCO1 synthesis of cytochrome C oxidase 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:34,957,358...34,971,684
Ensembl chr 5:34,957,785...34,971,661
JBrowse link
G USP19 ubiquitin specific peptidase 19 IEA Ensembl GO_REF:0000107 NCBI chr20:40,062,802...40,074,221
Ensembl chr20:40,064,599...40,074,082
JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 IEA Ensembl GO_REF:0000107 NCBI chr 8:71,318,730...71,324,743
Ensembl chr 8:71,321,625...71,322,992
JBrowse link
G BAG6 BAG cochaperone 6 ISO (MGI:MGI:3808636|PMID:18678708) UniProtKB PMID:18678708 MGI:MGI:3808636 NCBI chr12:1,126,730...1,141,978
Ensembl chr12:1,126,732...1,137,896
JBrowse link
G CAMLG calcium modulating ligand IEA Ensembl GO_REF:0000107 NCBI chr11:22,818,699...22,829,737
Ensembl chr11:22,818,743...22,829,736
JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 IEA Ensembl GO_REF:0000107 NCBI chr25:34,660,026...34,674,129
Ensembl chr25:34,660,553...34,674,037
JBrowse link
G CLEC16A C-type lectin domain containing 16A IEA Ensembl GO_REF:0000107 NCBI chr 6:31,560,940...31,757,100
Ensembl chr 6:31,562,834...31,757,678
JBrowse link
G DDRGK1 DDRGK domain containing 1 IEA Ensembl GO_REF:0000107 NCBI chr24:18,085,865...18,098,868
Ensembl chr24:18,084,725...18,097,157
JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H ISO (PMID:32269044) FlyBase PMID:32269044 NCBI chr13:16,105,960...16,201,902
Ensembl chr13:16,105,990...16,341,153
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase IEA Ensembl GO_REF:0000107 NCBI chr20:29,735,380...31,113,859
Ensembl chr20:30,356,572...31,113,859
JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 IEA Ensembl GO_REF:0000107 NCBI chr20:48,144,076...48,155,069
Ensembl chr20:48,150,498...48,157,191
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 IEA Ensembl GO_REF:0000107 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940
JBrowse link
G KLHL40 kelch like family member 40 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr23:11,812,268...11,820,426
Ensembl chr23:11,813,550...11,820,420
JBrowse link
G LOC102154748 E3 ubiquitin-protein ligase TRIM39 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr12:317,149...330,907
Ensembl chr12:319,413...329,427
JBrowse link
G MAP1A microtubule associated protein 1A ISO (MGI:MGI:5703671|PMID:26609151) ARUK-UCL PMID:26609151 MGI:MGI:5703671 NCBI chr30:10,361,871...10,382,780
Ensembl chr30:10,361,909...10,381,376
JBrowse link
G MTM1 myotubularin 1 ISO (MGI:MGI:5510937|PMID:23695157) MGI PMID:23695157 MGI:MGI:5510937 NCBI chr  X:118,820,644...118,917,166
Ensembl chr  X:118,820,494...118,916,368
JBrowse link
G N4BP1 NEDD4 binding protein 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:66,544,665...66,565,858
Ensembl chr 2:66,544,677...66,561,560
JBrowse link
G NOP53 NOP53 ribosome biogenesis factor IEA Ensembl GO_REF:0000107 NCBI chr 1:108,307,039...108,315,732
Ensembl chr 1:108,307,042...108,316,495
JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase IEA Ensembl GO_REF:0000107 NCBI chr  X:55,821,227...55,857,597
Ensembl chr  X:55,821,234...55,855,502
JBrowse link
G PARK7 Parkinsonism associated deglycase ISO (PMID:17015834) ParkinsonsUK-UCL PMID:17015834 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303
JBrowse link
G PBK PDZ binding kinase IEA Ensembl GO_REF:0000107 NCBI chr25:29,751,805...29,781,806
Ensembl chr25:29,751,848...29,781,300
JBrowse link
G RPL11 ribosomal protein L11 IEA Ensembl GO_REF:0000107 NCBI chr 2:75,781,210...75,785,614
Ensembl chr 2:75,781,091...75,785,605
JBrowse link
G RYBP RING1 and YY1 binding protein IEA Ensembl GO_REF:0000107 NCBI chr20:19,650,936...19,732,987
Ensembl chr20:19,615,426...19,729,474
JBrowse link
G SDCBP syndecan binding protein ISO (PMID:25893292) UniProtKB PMID:25893292 NCBI chr29:9,331,876...9,370,489 JBrowse link
G SENP1 SUMO specific peptidase 1 IEA Ensembl GO_REF:0000107 NCBI chr27:6,664,750...6,719,257
Ensembl chr27:6,664,818...6,714,479
JBrowse link
G SHH sonic hedgehog signaling molecule IEA Ensembl GO_REF:0000107 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903
JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 IEA Ensembl GO_REF:0000107 NCBI chr20:41,165,593...41,337,237
Ensembl chr20:41,165,522...41,335,917
JBrowse link
G TAF9 TATA-box binding protein associated factor 9 IEA Ensembl GO_REF:0000107 NCBI chr 2:54,403,908...54,406,857
Ensembl chr 2:54,390,411...54,406,872
JBrowse link
G TLK2 tousled like kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr 9:10,686,424...10,804,885
Ensembl chr 9:10,687,293...10,803,963
JBrowse link
G TTC36 tetratricopeptide repeat domain 36 ISO (MGI:MGI:6362140|PMID:31537781) MGI PMID:31537781 MGI:MGI:6362140 NCBI chr 5:15,207,400...15,211,905
Ensembl chr 5:15,207,403...15,211,853
JBrowse link
G UBXN1 UBX domain protein 1 IEA Ensembl GO_REF:0000107 NCBI chr18:53,977,937...53,982,108
Ensembl chr18:53,978,062...53,982,111
JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 ISO (PMID:23770237) UniProtKB PMID:23770237 NCBI chr38:6,004,595...6,045,999
Ensembl chr38:6,004,659...6,113,714
JBrowse link
G USP7 ubiquitin specific peptidase 7 IEA Ensembl GO_REF:0000107 NCBI chr 6:33,277,328...33,315,601
Ensembl chr 6:33,277,444...33,314,491
JBrowse link
G WAC WW domain containing adaptor with coiled-coil ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chr 2:17,504,949...17,588,037 JBrowse link
negative regulation of protein deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 ISO (PMID:15936278) BHF-UCL PMID:15936278 NCBI chr37:25,826,496...25,834,011
Ensembl chr37:25,827,713...25,833,144
JBrowse link
G TRIM21 tripartite motif containing 21 IEA Ensembl GO_REF:0000107 NCBI chr21:26,775,227...26,783,180
Ensembl chr21:26,775,672...26,783,725
JBrowse link
negative regulation of protein K48-linked deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase ISO (PMID:21097510) ParkinsonsUK-UCL PMID:21097510 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303
JBrowse link
G UBXN1 UBX domain protein 1 IEA Ensembl GO_REF:0000107 NCBI chr18:53,977,937...53,982,108
Ensembl chr18:53,978,062...53,982,111
JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP4 acid phosphatase 4 IEA Ensembl GO_REF:0000107 NCBI chr 1:106,051,901...106,056,137
Ensembl chr 1:106,051,901...106,056,137
JBrowse link
G CDH1 cadherin 1 ISO (MGI:MGI:3763814|PMID:17344476) MGI PMID:17344476 MGI:MGI:3763814 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878
JBrowse link
G FMR1 FMRP translational regulator 1 ISO Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:116,249,079...116,287,008
Ensembl chr  X:116,249,142...116,321,439
JBrowse link
G GAS1 growth arrest specific 1 ISS UniProtKB GO_REF:0000024 NCBI chr 1:72,927,346...72,930,119
Ensembl chr 1:72,927,670...72,928,827
JBrowse link
G GLG1 golgi glycoprotein 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:76,020,743...76,171,477
Ensembl chr 5:76,020,084...76,167,007
JBrowse link
G IL1R2 interleukin 1 receptor type 2 ISO (MGI:MGI:5468848|PMID:23395675) MGI PMID:23395675 MGI:MGI:5468848 NCBI chr10:40,967,532...41,003,659
Ensembl chr10:40,896,669...41,034,113
JBrowse link
G LRRK2 leucine rich repeat kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870
JBrowse link
G MDM2 MDM2 proto-oncogene ISO caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr 1:107,486,399...107,490,151
Ensembl chr 1:107,486,438...107,489,222
JBrowse link
G SNX12 sorting nexin 12 ISO (PMID:22709416) UniProtKB PMID:22709416 NCBI chr  X:55,441,271...55,450,767 JBrowse link
G TMEM59 transmembrane protein 59 IEA Ensembl GO_REF:0000107 NCBI chr 5:54,959,895...54,991,978
Ensembl chr 5:54,960,069...54,987,758
JBrowse link
G TMEM98 transmembrane protein 98 IEA Ensembl GO_REF:0000107 NCBI chr 9:40,130,421...40,144,120
Ensembl chr 9:40,128,885...40,144,181
JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chr26:16,228,831...16,244,104
Ensembl chr26:16,234,710...16,240,012
JBrowse link
negative regulation of proteolysis involved in cellular protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EFNA1 ephrin A1 IEA Ensembl GO_REF:0000107 NCBI chr 7:42,373,197...42,381,161
Ensembl chr 7:42,373,639...42,378,946
JBrowse link
G EPHA4 EPH receptor A4 IEA Ensembl GO_REF:0000107 NCBI chr37:27,670,143...27,809,642
Ensembl chr37:27,677,566...27,809,646
JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STYX serine/threonine/tyrosine interacting protein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:28,949,732...28,990,455
Ensembl chr 8:28,950,061...28,986,812
JBrowse link
negative regulation of serine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA8L1 annexin A8-like 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:34,862,992...34,878,535 JBrowse link
G CR1L complement C3b/C4b receptor 1 like ISO (PMID:6910481) UniProtKB PMID:6910481 NCBI chr 7:6,484,281...6,549,677 JBrowse link
G SERPINA1 serpin family A member 1 ISO RGD PMID:19240864 RGD:7411612 NCBI chr 8:63,388,498...63,400,377
Ensembl chr 8:63,376,945...63,398,435
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:42,112,015...42,120,738
Ensembl chr 2:42,112,016...42,120,706
JBrowse link
G SPINK2 serine peptidase inhibitor, Kazal type 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:48,952,869...48,964,862
Ensembl chr13:48,944,135...48,964,831
JBrowse link
G SPINK5 serine peptidase inhibitor Kazal type 5 IEA Ensembl GO_REF:0000107 NCBI chr 2:42,285,537...42,365,637
Ensembl chr 2:42,285,537...42,365,690
JBrowse link
G SPINK6 serine peptidase inhibitor Kazal type 6 ISO (MGI:MGI:5560845|PMID:24352040) MGI PMID:24352040 MGI:MGI:5560845 NCBI chr 2:42,409,038...42,425,540
Ensembl chr 2:42,415,406...42,425,535
JBrowse link
negative regulation of serine-type peptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPINK5 serine peptidase inhibitor Kazal type 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:42,285,537...42,365,637
Ensembl chr 2:42,285,537...42,365,690
JBrowse link
G SPINK6 serine peptidase inhibitor Kazal type 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:42,409,038...42,425,540
Ensembl chr 2:42,415,406...42,425,535
JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A ISO (MGI:MGI:4461099|PMID:20100865) MGI PMID:20100865 MGI:MGI:4461099 NCBI chr12:4,095,394...4,274,428
Ensembl chr12:4,095,490...4,272,654
JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr24:20,333,593...20,390,341 JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr 2:58,361,328...58,441,701
Ensembl chr 2:58,360,838...58,432,371
JBrowse link
G HFE homeostatic iron regulator IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr16:9,066,957...9,256,916
Ensembl chr16:9,066,970...9,244,526
JBrowse link
G LOC102154748 E3 ubiquitin-protein ligase TRIM39 ISO (PMID:19100260) BHF-UCL PMID:19100260 NCBI chr12:317,149...330,907
Ensembl chr12:319,413...329,427
JBrowse link
G PDCL3 phosducin like 3 IEA Ensembl GO_REF:0000107 NCBI chr10:42,214,127...42,223,986
Ensembl chr10:42,215,120...42,223,906
JBrowse link
G PML PML nuclear body scaffold IEA Ensembl GO_REF:0000107 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741
JBrowse link
G PSEN1 presenilin 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532
JBrowse link
G PSEN2 presenilin 2 ISO (MGI:MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:MGI:4887523 NCBI chr 7:38,147,157...38,163,023
Ensembl chr 7:38,147,173...38,166,722
JBrowse link
G QRICH2 glutamine rich 2 ISO (PMID:30683861)
(MGI:MGI:6277293|PMID:30683861)
UniProt PMID:30683861 MGI:MGI:6277293 NCBI chr 9:4,395,501...4,408,302
Ensembl chr 9:4,374,650...4,408,299
JBrowse link
G RPL11 ribosomal protein L11 ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 2:75,781,210...75,785,614
Ensembl chr 2:75,781,091...75,785,605
JBrowse link
G RPL23 ribosomal protein L23 IEA Ensembl GO_REF:0000107 NCBI chr 9:23,397,143...23,403,060
Ensembl chr 9:23,262,282...23,403,054
JBrowse link
G RPL5 ribosomal protein L5 ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 6:56,207,171...56,216,030
Ensembl chr 6:56,207,173...56,215,956
JBrowse link
G RPS7 ribosomal protein S7 ISO (PMID:17310983) CAFA PMID:17310983 NCBI chr17:2,139,011...2,143,160
Ensembl chr17:2,138,779...2,143,178
JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat containing alpha ISO (PMID:23129660) UniProtKB PMID:23129660 NCBI chr20:56,432,688...56,451,438
Ensembl chr20:56,441,724...56,450,215
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling ISO (MGI:MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:MGI:4355593 NCBI chr28:14,992,989...15,115,499
Ensembl chr28:14,992,618...15,112,389
JBrowse link
G TAF1 TATA-box binding protein associated factor 1 ISO (PMID:17237821) ParkinsonsUK-UCL PMID:17237821 NCBI chr  X:55,693,091...55,764,268 JBrowse link
G WNT1 Wnt family member 1 ISO (MGI:MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:MGI:3628833 NCBI chr27:5,588,151...5,592,254
Ensembl chr27:5,574,940...5,592,060
JBrowse link
negative regulation of ubiquitin-specific protease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase ISO (PMID:21097510) ParkinsonsUK-UCL PMID:21097510 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303
JBrowse link
G UBXN1 UBX domain protein 1 IEA Ensembl GO_REF:0000107 NCBI chr18:53,977,937...53,982,108
Ensembl chr18:53,978,062...53,982,111
JBrowse link
zymogen inhibition term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FURIN furin, paired basic amino acid cleaving enzyme ISO (PMID:11799113), (PMID:9130696) UniProt PMID:9130696, PMID:11799113 NCBI chr 3:53,357,491...53,368,285
Ensembl chr 3:53,358,045...53,365,423
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    metabolic process 10658
      primary metabolic process 9470
        protein metabolic process 5384
          proteolysis 1650
            negative regulation of proteolysis 330
              negative regulation of membrane protein ectodomain proteolysis 7
              negative regulation of peptidase activity + 235
              negative regulation of protein desumoylation 0
              negative regulation of protein deubiquitination + 4
              negative regulation of protein processing + 31
              negative regulation of proteolysis involved in cellular protein catabolic process + 68
Path 2
Term Annotations click to browse term
  biological_process 16187
    metabolic process 10658
      organic substance metabolic process 10133
        macromolecule metabolic process 8796
          protein metabolic process 5384
            cellular protein metabolic process 4816
              regulation of cellular protein metabolic process 2608
                negative regulation of cellular protein metabolic process 1039
                  negative regulation of proteolysis 330
                    negative regulation of membrane protein ectodomain proteolysis 7
                    negative regulation of peptidase activity + 235
                    negative regulation of protein desumoylation 0
                    negative regulation of protein deubiquitination + 4
                    negative regulation of protein processing + 31
                    negative regulation of proteolysis involved in cellular protein catabolic process + 68
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.