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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of proteolysis
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Accession:GO:0045861 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Synonyms:exact_synonym: down regulation of proteolysis;   downregulation of proteolysis;   negative regulation of peptidolysis
 narrow_synonym: inhibition of proteolysis


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negative regulation of proteolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G Bag6 BAG cochaperone 6 ISO (MGI:MGI:3774040|PMID:18056262) UniProtKB PMID:18056262 MGI:MGI:3774040 NCBI chrNW_004936727:1,866,235...1,885,266 JBrowse link
G Camk2n1 calcium/calmodulin dependent protein kinase II inhibitor 1 ISO (PMID:18305109) UniProtKB PMID:18305109 NCBI chrNW_004936474:6,463,691...6,466,641 JBrowse link
G Cdk5 cyclin dependent kinase 5 ISO (PMID:24548080) ParkinsonsUK-UCL PMID:24548080 NCBI chrNW_004936527:6,478,934...6,483,848 JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:1346962|PMID:10527801) MGI PMID:10527801 MGI:MGI:1346962 NCBI chrNW_004936501:11,955,334...11,967,338 JBrowse link
G Csta cystatin A ISO (PMID:3488317) UniProtKB PMID:3488317 NCBI chrNW_004936536:8,649,890...8,662,472 JBrowse link
G Cstb cystatin B ISO (PMID:3488317) UniProtKB PMID:3488317 NCBI chrNW_004936500:502,444...503,307 JBrowse link
G F2 coagulation factor II, thrombin ISO (PMID:1695900) BHF-UCL PMID:1695900 NCBI chrNW_004936562:2,371,725...2,388,617 JBrowse link
G Hdac6 histone deacetylase 6 ISO (PMID:18356165) BHF-UCL PMID:18356165 NCBI chrNW_004936721:757,500...778,416 JBrowse link
G Ide insulin degrading enzyme ISO inhibits activity of the multicatalytic proteinase complex (proteasome) RGD PMID:9000694 RGD:1627643 NCBI chrNW_004936601:2,230,477...2,318,562 JBrowse link
G Ins insulin ISO (PMID:3553851) BHF-UCL PMID:3553851 NCBI chrNW_004936816:1,002,137...1,003,357 JBrowse link
G Kng1 kininogen 1 ISO (PMID:3488317) UniProtKB
RGD
PMID:3356189, PMID:3488317 RGD:1600550 NCBI chrNW_004936578:3,255,335...3,281,296 JBrowse link
G Nr1h2 nuclear receptor subfamily 1 group H member 2 ISO (MGI:MGI:3822255|PMID:18806227) BHF-UCL PMID:18806227 MGI:MGI:3822255 NCBI chrNW_004936889:223,137...229,968 JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 ISO (MGI:MGI:3822255|PMID:18806227) BHF-UCL PMID:18806227 MGI:MGI:3822255 NCBI chrNW_004936562:1,937,665...1,946,680 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:15161606 RGD:1625251 NCBI chrNW_004936480:1,188,408...1,273,210 JBrowse link
G Plat plasminogen activator, tissue type ISO (PMID:1695900) BHF-UCL PMID:1695900 NCBI chrNW_004936785:476,200...503,371 JBrowse link
G Rab23 RAB23, member RAS oncogene family ISO (MGI:MGI:3612806|PMID:16364285) MGI PMID:16364285 MGI:MGI:3612806 NCBI chrNW_004936476:4,095,829...4,127,714 JBrowse link
G Serpina5 serpin family A member 5 ISO RGD PMID:16088033 RGD:1580291 NCBI chrNW_004936846:141,334...150,381 JBrowse link
G Serpinb10 serpin family B member 10 ISO RGD PMID:11986314 RGD:634009 NCBI chrNW_004936497:1,782,142...1,797,968 JBrowse link
G Serpine2 serpin family E member 2 ISO PMID:17379830
(PMID:17379830), (PMID:3997857)
BHF-UCL PMID:3997857, PMID:17379830 RGD:8553298 NCBI chrNW_004936569:5,642,328...5,668,278 JBrowse link
G Spink5 serine peptidase inhibitor Kazal type 5 ISO (MGI:MGI:3055648|PMID:15466487) MGI PMID:15466487 MGI:MGI:3055648 NCBI chrNW_004936504:6,653,703...6,750,110 JBrowse link
G Spink9 serine peptidase inhibitor Kazal type 9 ISO (MGI:MGI:3662793|PMID:16930550) MGI PMID:16930550 MGI:MGI:3662793 NCBI chrNW_004936504:6,405,158...6,410,014 JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:17532789 RGD:2290425 NCBI chrNW_004936594:3,232,433...3,244,241 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO RGD PMID:17532789 RGD:2290425 NCBI chrNW_004936492:6,996,627...7,046,137 JBrowse link
G Tm4sf20 transmembrane 4 L six family member 20 ISO (PMID:25310401), (PMID:27499293) UniProtKB PMID:25310401, PMID:27499293 NCBI chrNW_004936525:8,587,236...8,600,780 JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:5468878|PMID:23277542) MGI PMID:23277542 MGI:MGI:5468878 NCBI chrNW_004936595:919,807...935,367 JBrowse link
inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin ISO (PMID:2407243) CAFA PMID:2407243 NCBI chrNW_004936523:6,688,153...6,798,184 JBrowse link
G Cst7 cystatin F ISO (MGI:MGI:5904382|PMID:28251676) MGI PMID:28251676 MGI:MGI:5904382 NCBI chrNW_004936620:853,533...870,609 JBrowse link
G Nol3 nucleolar protein 3 ISO PMID:17292893
PMID:16639714
UniProt PMID:16639714, PMID:17292893 RGD:10047164, RGD:10047212 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l12 BCL2 like 12 ISO (PMID:22262180) UniProtKB PMID:22262180 NCBI chrNW_004936664:3,482,562...3,488,663 JBrowse link
G Fcmr Fc fragment of IgM receptor ISO (MGI:MGI:3576402|PMID:15632112) MGI PMID:15632112 MGI:MGI:3576402 NCBI chrNW_004936557:5,707,138...5,718,192 JBrowse link
G Nol3 nucleolar protein 3 ISO (PMID:15509781) UniProtKB PMID:15509781 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Xiap X-linked inhibitor of apoptosis ISO (MGI:MGI:2681362|PMID:14623868) MGI PMID:14623868 MGI:MGI:2681362 NCBI chrNW_004936479:6,677,533...6,724,800 JBrowse link
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 ISO (MGI:MGI:5811968|PMID:27179792)
(PMID:27179792)
ARUK-UCL PMID:27179792 MGI:MGI:5811968 NCBI chrNW_004936469:44,128,308...44,185,739 JBrowse link
G Sorl1 sortilin related receptor 1 ISO (PMID:16407538)
(PMID:17855360), (PMID:21989385)
(MGI:MGI:3801250|PMID:18362153)
Alzheimers_University_of_Toronto PMID:16407538, PMID:17855360, PMID:18362153, PMID:21989385 MGI:MGI:3801250 NCBI chrNW_004936542:6,192,407...6,352,835 JBrowse link
negative regulation of cysteine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:23690069 RGD:13792722 NCBI chrNW_004936599:2,437,061...2,456,141 JBrowse link
G Htt huntingtin ISO RGD PMID:17124493 RGD:6902918 NCBI chrNW_004936477:20,443,101...20,577,167 JBrowse link
G LOC101959548 beta-casein ISO (PMID:12788072) CAFA PMID:12788072 NCBI chrNW_004936598:4,683,300...4,687,605 JBrowse link
G Ltf lactotransferrin ISO (PMID:12788072) CAFA PMID:12788072 NCBI chrNW_004936596:344,287...373,788 JBrowse link
G Mt3 metallothionein 3 ISO (PMID:18554677) UniProtKB PMID:18554677 NCBI chrNW_004936475:8,864,512...8,866,516 JBrowse link
G Pcid2 PCI domain containing 2 ISO (PMID:20870947) UniProtKB PMID:20870947 NCBI chrNW_004936472:440,440...464,116 JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO RGD PMID:15211592 RGD:1625666 NCBI chrNW_004936619:597,970...618,564 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO (MGI:MGI:5294538|PMID:18977203) UniProtKB PMID:18977203 MGI:MGI:5294538 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO caspase 3 RGD PMID:18348079 RGD:2313324 NCBI chrNW_004936661:2,652,568...2,694,039 JBrowse link
G Aqp1 aquaporin 1 (Colton blood group) ISO (PMID:21215257) UniProtKB PMID:21215257 NCBI chrNW_004936478:7,146,997...7,160,369 JBrowse link
G Arl6ip1 ADP ribosylation factor like GTPase 6 interacting protein 1 ISO (PMID:12754298) UniProtKB PMID:12754298 NCBI chrNW_004936501:4,648,699...4,670,786 JBrowse link
G Arrb1 arrestin beta 1 ISO (MGI:MGI:4453294|PMID:19915011) UniProtKB PMID:19915011 MGI:MGI:4453294 NCBI chrNW_004936498:4,089,621...4,172,749 JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:19171933 RGD:5510006 NCBI chrNW_004936677:3,173,054...3,181,475 JBrowse link
G Birc5 baculoviral IAP repeat containing 5 ISO (PMID:12773388)
(PMID:9859993)
UniProtKB PMID:9859993, PMID:12773388 NCBI chrNW_004936594:2,812,165...2,820,618 JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO (PMID:19047049) UniProtKB PMID:19047049 NCBI chrNW_004936533:2,949,026...3,033,166 JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D ISO (PMID:15750620) BHF-UCL PMID:15750620 NCBI chrNW_004936659:840,602...843,078 JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator ISO (MGI:MGI:3612311|PMID:16263940) MGI PMID:16263940 MGI:MGI:3612311 NCBI chrNW_004936726:381,888...425,565 JBrowse link
G Cryaa crystallin alpha A ISO (MGI:MGI:3617146|PMID:16439475) MGI PMID:16439475 MGI:MGI:3617146 NCBI chrNW_004936500:931,804...935,185 JBrowse link
G Cryab crystallin alpha B ISO (MGI:MGI:3617146|PMID:16439475) MGI PMID:16439475 MGI:MGI:3617146 NCBI chrNW_004936612:2,532,851...2,536,473 JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 ISO (PMID:16193064) UniProtKB PMID:16193064 NCBI chrNW_004936485:17,966,993...18,021,191 JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked ISO (PMID:18846110) UniProtKB PMID:18846110 NCBI chrNW_004936502:7,770,896...7,820,555 JBrowse link
G Dhcr24 24-dehydrocholesterol reductase ISO (PMID:11007892) UniProtKB PMID:11007892 NCBI chrNW_004936522:6,423,561...6,447,363 JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 ISO (PMID:10411904) UniProtKB PMID:10411904 NCBI chrNW_004936694:43,898...74,939 JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 ISO (PMID:11896048) UniProtKB PMID:11896048 NCBI chrNW_004936797:332,962...377,397 JBrowse link
G Dpep1 dipeptidase 1 ISO (PMID:20435919) UniProtKB PMID:20435919 NCBI chrNW_004936641:379,112...384,711 JBrowse link
G Ep300 E1A binding protein p300 ISO cardiac myocytes RGD PMID:22562121 RGD:7327216 NCBI chrNW_004936492:696,982...778,132 JBrowse link
G Fabp1 fatty acid binding protein 1 ISO (PMID:16175609) UniProtKB PMID:16175609 NCBI chrNW_004936712:738,361...743,073 JBrowse link
G Fnip1 folliculin interacting protein 1 ISO (MGI:MGI:5444323|PMID:22709692) MGI PMID:22709692 MGI:MGI:5444323 NCBI chrNW_004936647:3,329,097...3,428,170 JBrowse link
G Gas6 growth arrest specific 6 ISO (PMID:16723520) UniProtKB PMID:16723520 NCBI chrNW_004936472:27,116...57,158 JBrowse link
G Gpi glucose-6-phosphate isomerase ISO RGD PMID:12615053 RGD:1600634 NCBI chrNW_004936570:1,582,120...1,608,537 JBrowse link
G Gpx1 glutathione peroxidase 1 ISO (PMID:12221075) BHF-UCL PMID:12221075 NCBI chrNW_004936529:997,943...999,123 JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 ISO RGD PMID:15102845 RGD:1304324 NCBI chrNW_004936475:9,091,115...9,102,101 JBrowse link
G Hgf hepatocyte growth factor ISO (PMID:20655899) BHF-UCL PMID:20655899 NCBI chrNW_004936734:354,798...428,356 JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO reduced cleavage of Casp8 and Casp9 in brain following hypoxic/ischemic injury
(MGI:MGI:2177029|PMID:11879190)
RGD
MGI
PMID:11879190, PMID:16397188 MGI:MGI:2177029, RGD:1626654 NCBI chrNW_004936727:1,718,952...1,721,691 JBrowse link
G Igbp1 immunoglobulin binding protein 1 ISO (PMID:17438131) UniProtKB PMID:17438131 NCBI chrNW_004936762:1,292,572...1,319,145 JBrowse link
G Igf1 insulin like growth factor 1 ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Il24 interleukin 24 ISO (MGI:MGI:3821693|PMID:18708357) MGI PMID:18708357 MGI:MGI:3821693 NCBI chrNW_004936557:5,719,592...5,727,113 JBrowse link
G Ints1 integrator complex subunit 1 ISO (MGI:MGI:3722560|PMID:17544522) MGI PMID:17544522 MGI:MGI:3722560 NCBI chrNW_004936754:1,597,574...1,626,578 JBrowse link
G Klf4 Kruppel like factor 4 ISO (PMID:20551324) BHF-UCL PMID:20551324 NCBI chrNW_004936559:5,105,456...5,109,970 JBrowse link
G Lamp3 lysosomal associated membrane protein 3 ISO (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chrNW_004936566:365,326...394,985 JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 ISO (PMID:12773388) UniProtKB PMID:12773388 NCBI chrNW_004936704:1,830,470...1,835,966 JBrowse link
G LOC101965545 NADPH--cytochrome P450 reductase ISO caspase-3 RGD PMID:19264869 RGD:2316785 NCBI chrNW_004936543:2,275,981...2,327,931 JBrowse link
G Map2k5 mitogen-activated protein kinase kinase 5 ISO PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chrNW_004936471:27,491,255...27,728,572 JBrowse link
G Mdm2 MDM2 proto-oncogene ISO caspase-2, caspase-3 RGD PMID:19850968 RGD:2317361 NCBI chrNW_004936545:6,709,903...6,732,334 JBrowse link
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 ISO (MGI:MGI:5142343|PMID:21730291) UniProtKB PMID:21730291 MGI:MGI:5142343 NCBI chrNW_004936564:5,568,613...5,579,402 JBrowse link
G Mrtfa myocardin related transcription factor A ISO (MGI:MGI:2183867|PMID:12019265) MGI PMID:12019265 MGI:MGI:2183867 NCBI chrNW_004936492:1,234,025...1,384,838 JBrowse link
G Mt3 metallothionein 3 ISO (PMID:16387743) UniProtKB PMID:16387743 NCBI chrNW_004936475:8,864,512...8,866,516 JBrowse link
G Naip NLR family apoptosis inhibitory protein ISO (PMID:11896143) UniProtKB PMID:11896143 NCBI chrNW_004936549:5,000,526...5,069,110 JBrowse link
G Nol3 nucleolar protein 3 ISO PMID:19001025 UniProt PMID:19001025 RGD:8553292 NCBI chrNW_004936475:17,644,299...17,648,213 JBrowse link
G Nr4a1 nuclear receptor subfamily 4 group A member 1 ISO (MGI:MGI:2667579|PMID:12815108) MGI PMID:12815108 MGI:MGI:2667579 NCBI chrNW_004936512:9,486,096...9,508,338 JBrowse link
G Pax2 paired box 2 ISO (PMID:10980123), (PMID:17357786) UniProtKB PMID:10980123, PMID:17357786 NCBI chrNW_004936600:4,850,594...4,939,010 JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO (PMID:21716255) CAFA PMID:21716255 NCBI chrNW_004936697:2,440,943...2,453,897 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO (MGI:MGI:5474549|PMID:21716255) CAFA PMID:21716255 MGI:MGI:5474549 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Ptma prothymosin alpha ISO RGD PMID:12522243 RGD:734494 NCBI chrNW_004936525:5,253,723...5,258,300 JBrowse link
G Rag1 recombination activating 1 ISO (MGI:MGI:3531056|PMID:15728238) MGI PMID:15728238 MGI:MGI:3531056 NCBI chrNW_004936533:1,817,135...1,827,393 JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 ISO (PMID:18402937) UniProtKB PMID:18402937 NCBI chrNW_004936474:10,996,867...11,030,504 JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 ISO (PMID:18402937) UniProtKB PMID:18402937 NCBI chrNW_004936624:3,897,878...4,005,664 JBrowse link
G Sfn stratifin ISO (PMID:11574543) HGNC PMID:11574543 NCBI chrNW_004936474:11,274,927...11,279,427 JBrowse link
G Sfrp2 secreted frizzled related protein 2 ISO (MGI:MGI:3702339|PMID:17251350) MGI PMID:17251350 MGI:MGI:3702339 NCBI chrNW_004936576:604,174...612,440 JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 ISO (PMID:21586138) UniProtKB PMID:21586138 NCBI chrNW_004936516:1,267,128...1,429,040 JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 ISO (PMID:21586138) UniProtKB PMID:21586138 NCBI chrNW_004936758:1,115,980...1,132,225 JBrowse link
G Snca synuclein alpha ISO (PMID:10818098) UniProtKB PMID:10818098 NCBI chrNW_004936685:2,077,017...2,175,298 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO (PMID:19767770) UniProtKB PMID:19767770 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
G Thbs1 thrombospondin 1 ISO (PMID:18653767) UniProtKB PMID:18653767 NCBI chrNW_004936471:3,064,466...3,081,125 JBrowse link
G Tnf tumor necrosis factor ISO (PMID:31124343) ARUK-UCL PMID:31124343 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 ISO (PMID:15735003) BHF-UCL PMID:15735003 NCBI chrNW_004936668:500,815...503,158 JBrowse link
G Usp47 ubiquitin specific peptidase 47 ISO (PMID:19966869) UniProtKB PMID:19966869 NCBI chrNW_004936528:6,483,898...6,596,136 JBrowse link
G Vegfa vascular endothelial growth factor A ISO (PMID:18386220) UniProtKB PMID:18386220 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
G Wnt9a Wnt family member 9A ISO (MGI:MGI:4368092|PMID:19422823) MGI PMID:19422823 MGI:MGI:4368092 NCBI chrNW_004936864:216,381...245,885 JBrowse link
G Xiap X-linked inhibitor of apoptosis ISO (MGI:MGI:2183141|PMID:12011074), (MGI:MGI:2183348|PMID:12153481)
(PMID:11583623)
MGI
UniProtKB
PMID:11583623, PMID:12011074, PMID:12153481 MGI:MGI:2183141, MGI:MGI:2183348 NCBI chrNW_004936479:6,677,533...6,724,800 JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Caap1 caspase activity and apoptosis inhibitor 1 ISO (PMID:21980415) UniProtKB PMID:21980415 NCBI chrNW_004936611:2,710,512...2,761,484 JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO (PMID:22984561) CACAO PMID:22984561 NCBI chrNW_004936514:7,038,240...7,045,873 JBrowse link
G Nle1 notchless homolog 1 ISO (MGI:MGI:5468737|PMID:23231322) MGI PMID:23231322 MGI:MGI:5468737 NCBI chrNW_004936538:101,245...109,796 JBrowse link
G Park7 Parkinsonism associated deglycase ISO (PMID:21785459) ParkinsonsUK-UCL PMID:21785459 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
G Pih1d1 PIH1 domain containing 1 ISO (PMID:21078300) UniProtKB PMID:21078300 NCBI chrNW_004936664:3,321,278...3,326,720 JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO (PMID:22984561) CACAO PMID:22984561 NCBI chrNW_004936706:840,968...855,552 JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pak2 p21 (RAC1) activated kinase 2 ISO (PMID:21555521) UniProtKB PMID:21555521 NCBI chrNW_004936784:1,351,034...1,391,992 JBrowse link
G Rffl ring finger and FYVE like domain containing E3 ubiquitin protein ligase ISO (PMID:15069192) UniProtKB PMID:15069192 NCBI chrNW_004936538:139,690...203,600 JBrowse link
G Rnf34 ring finger protein 34 ISO (PMID:15069192) UniProtKB PMID:15069192 NCBI chrNW_004936558:2,901,386...2,918,976 JBrowse link
negative regulation of endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin ISO RGD PMID:19240864 RGD:7411612 NCBI chrNW_004936870:424,832...468,303 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G Crb2 crumbs cell polarity complex component 2 ISO (PMID:20299451) UniProtKB PMID:20299451 NCBI chrNW_004936487:11,793,078...11,813,803 JBrowse link
G Fetub fetuin B ISO (MGI:MGI:5488517|PMID:23562279) UniProtKB PMID:23562279 MGI:MGI:5488517 NCBI chrNW_004936578:3,302,005...3,310,536 JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO (PMID:22832495) UniProtKB PMID:22832495 NCBI chrNW_004936709:1,243,149...1,247,782 JBrowse link
G LOC101976708 testican-3 ISO (PMID:11751414) UniProtKB PMID:11751414 NCBI chrNW_004936851:316,979...443,444 JBrowse link
G Renbp renin binding protein ISO RGD PMID:11926999 RGD:727355 NCBI chrNW_004936809:817,392...823,926 JBrowse link
G Serpinb1 serpin family B member 1 ISO (PMID:30692621) UniProt PMID:30692621 NCBI chrNW_004936633:3,917,430...3,926,046 JBrowse link
G Serpine1 serpin family E member 1 ISO (PMID:1695900) RGD
BHF-UCL
PMID:1695900, PMID:10717410 RGD:8547889 NCBI chrNW_004936543:1,032,543...1,040,956 JBrowse link
G Spock1 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 ISO (PMID:14511383) UniProtKB PMID:14511383 NCBI chrNW_004936597:4,000,433...4,493,920 JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO (PMID:3903517) UniProtKB PMID:3903517 NCBI chrNW_004936502:13,345,936...13,350,170 JBrowse link
G Vtn vitronectin ISO (PMID:1695900) BHF-UCL PMID:1695900 NCBI chrNW_004936538:4,522,275...4,525,245 JBrowse link
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sgta small glutamine rich tetratricopeptide repeat containing alpha ISO (PMID:23129660) UniProtKB PMID:23129660 NCBI chrNW_004936588:1,599,453...1,616,480 JBrowse link
G Svip small VCP interacting protein ISO (PMID:17872946) UniProtKB PMID:17872946 NCBI chrNW_004936654:3,452,781...3,459,161 JBrowse link
G Usp14 ubiquitin specific peptidase 14 ISO (PMID:19135427) ParkinsonsUK-UCL PMID:19135427 NCBI chrNW_004936550:640,331...675,703 JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp11 aquaporin 11 ISO (MGI:MGI:3813160|PMID:18606867) UniProt PMID:18606867 MGI:MGI:3813160 NCBI chrNW_004936498:6,213,583...6,237,273 JBrowse link
G Ubxn1 UBX domain protein 1 ISO (PMID:21135095) ParkinsonsUK-UCL PMID:21135095 NCBI chrNW_004936581:584,519...587,863 JBrowse link
G Usp25 ubiquitin specific peptidase 25 ISO (PMID:22590560) ParkinsonsUK-UCL PMID:22590560 NCBI chrNW_004936505:8,613,588...8,683,560 JBrowse link
negative regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 ISO (PMID:18383040) BHF-UCL PMID:18383040 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Lrig2 leucine rich repeats and immunoglobulin like domains 2 ISO (MGI:MGI:5702499|PMID:26651291) MGI PMID:26651291 MGI:MGI:5702499 NCBI chrNW_004936690:1,591,741...1,642,183 JBrowse link
G Ptpn3 protein tyrosine phosphatase non-receptor type 3 ISO (PMID:12207026) BHF-UCL PMID:12207026 NCBI chrNW_004936559:3,436,114...3,547,316 JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO (PMID:12714508) UniProtKB PMID:12714508 NCBI chrNW_004936502:13,345,936...13,350,170 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO (PMID:18383040) BHF-UCL PMID:18383040 NCBI chrNW_004936492:6,996,627...7,046,137 JBrowse link
negative regulation of metalloendopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Reck reversion inducing cysteine rich protein with kazal motifs ISO (MGI:MGI:5659805|PMID:24812324)
(PMID:18194466)
BHF-UCL
UniProt
PMID:18194466, PMID:24812324 MGI:MGI:5659805 NCBI chrNW_004936524:4,021,666...4,099,703 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO (MGI:MGI:5659805|PMID:24812324) BHF-UCL PMID:24812324 MGI:MGI:5659805 NCBI chrNW_004936492:6,996,627...7,046,137 JBrowse link
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Picalm phosphatidylinositol binding clathrin assembly protein ISO (MGI:MGI:5432454|PMID:22539346) Alzheimers_University_of_Toronto PMID:22539346 MGI:MGI:5432454 NCBI chrNW_004936498:13,785,638...13,885,931 JBrowse link
G Sorl1 sortilin related receptor 1 ISO (MGI:MGI:3801250|PMID:18362153)
(PMID:17855360), (PMID:21989385)
Alzheimers_University_of_Toronto PMID:17855360, PMID:18362153, PMID:21989385 MGI:MGI:3801250 NCBI chrNW_004936542:6,192,407...6,352,835 JBrowse link
negative regulation of metallopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Timp1 TIMP metallopeptidase inhibitor 1 ISO (PMID:9573338) UniProtKB PMID:9573338 NCBI chrNW_004936502:13,345,936...13,350,170 JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO (PMID:9573338) UniProtKB PMID:9573338 NCBI chrNW_004936594:3,232,433...3,244,241 JBrowse link
negative regulation of peptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin ISO (MGI:MGI:5295525|PMID:21849499) MGI PMID:21849499 MGI:MGI:5295525 NCBI chrNW_004936523:6,688,153...6,798,184 JBrowse link
G Cst7 cystatin F ISO (MGI:MGI:6294189|PMID:18256700)
(PMID:15752368), (PMID:18256700), (PMID:22365146)
ARUK-UCL PMID:15752368, PMID:18256700, PMID:22365146 MGI:MGI:6294189 NCBI chrNW_004936620:853,533...870,609 JBrowse link
G Csta cystatin A ISO (PMID:6203523) BHF-UCL PMID:6203523 NCBI chrNW_004936536:8,649,890...8,662,472 JBrowse link
G Cstb cystatin B ISO (PMID:6203523) BHF-UCL PMID:6203523 NCBI chrNW_004936500:502,444...503,307 JBrowse link
G Ecm1 extracellular matrix protein 1 ISO (PMID:16512877) UniProtKB PMID:16512877 NCBI chrNW_004936580:750,423...756,765 JBrowse link
G Serpine2 serpin family E member 2 ISO (MGI:MGI:3521551|PMID:15509762), (MGI:MGI:3810206|PMID:18398001) MGI PMID:15509762, PMID:18398001 MGI:MGI:3521551, MGI:MGI:3810206 NCBI chrNW_004936569:5,642,328...5,668,278 JBrowse link
G Spink1 serine peptidase inhibitor Kazal type 1 ISO (MGI:MGI:72783|PMID:3428272) MGI PMID:3428272 MGI:MGI:72783 NCBI chrNW_004936504:6,975,044...6,981,304 JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpb2 carboxypeptidase B2 ISO RGD PMID:23369837 RGD:7243115 NCBI chrNW_004936857:577,067...609,855 JBrowse link
G Ctsz cathepsin Z ISO (PMID:19433310) CAFA PMID:19433310 NCBI chrNW_004936530:1,482,007...1,490,685 JBrowse link
G Serpine1 serpin family E member 1 ISO (MGI:MGI:4418017|PMID:19855083)
(PMID:8508955)
(PMID:18835034), (PMID:19855083)
BHF-UCL PMID:8508955, PMID:18835034, PMID:19855083 MGI:MGI:4418017 NCBI chrNW_004936543:1,032,543...1,040,956 JBrowse link
G Serpine2 serpin family E member 2 ISO (MGI:MGI:4418017|PMID:19855083)
(PMID:19855083)
BHF-UCL PMID:19855083 MGI:MGI:4418017 NCBI chrNW_004936569:5,642,328...5,668,278 JBrowse link
G Serpinf2 serpin family F member 2 ISO (PMID:134998) BHF-UCL PMID:134998 NCBI chrNW_004936538:7,870,898...7,877,279 JBrowse link
G Thbs1 thrombospondin 1 ISO (PMID:6438154) BHF-UCL PMID:6438154 NCBI chrNW_004936471:3,064,466...3,081,125 JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase ISO (PMID:8175643) CAFA PMID:8175643 NCBI chrNW_004936559:226,481...237,258 JBrowse link
G F8a1 coagulation factor VIII associated 1 ISO (PMID:27815841) UniProt PMID:27815841 NCBI chrNW_004936927:234,162...236,881 JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 ISO (PMID:21669198) BHF-UCL PMID:21669198 NCBI chrNW_004936475:24,238,262...24,249,249 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO PMID:17517623
(MGI:MGI:6148636|PMID:17517623)
ARUK-UCL PMID:17517623 MGI:MGI:6148636, RGD:13514081 NCBI chrNW_004936476:15,830,459...15,836,994 JBrowse link
G Lamp3 lysosomal associated membrane protein 3 ISO (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chrNW_004936566:365,326...394,985 JBrowse link
G LOC101974307 protein SCO1 homolog, mitochondrial ISO (MGI:MGI:5643882|PMID:25683716) MGI PMID:25683716 MGI:MGI:5643882 NCBI chrNW_004936595:3,523,789...3,537,933 JBrowse link
G LOC101977674 oligophrenin-1 ISO (MGI:MGI:5303043|PMID:21874017) UniProtKB PMID:21874017 MGI:MGI:5303043 NCBI chrNW_004936635:6,966...243,209 JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 ISO (PMID:29295817) UniProtKB PMID:29295817 NCBI chrNW_004936469:18,966,239...19,016,829 JBrowse link
G Prkcg protein kinase C gamma ISO (MGI:MGI:5467682|PMID:23185022) UniProtKB PMID:23185022 MGI:MGI:5467682 NCBI chrNW_004936994:87,525...105,125 JBrowse link
G Psme3ip1 proteasome activator subunit 3 interacting protein 1 ISO (PMID:29934401) UniProt PMID:29934401 NCBI chrNW_004936475:9,266,778...9,294,173 JBrowse link
G Psmf1 proteasome inhibitor subunit 1 ISO (PMID:10764772) UniProtKB PMID:10764772 NCBI chrNW_004936485:17,485,600...17,517,642 JBrowse link
G Usp19 ubiquitin specific peptidase 19 ISO (MGI:MGI:5614537|PMID:25088257) ParkinsonsUK-UCL PMID:25088257 MGI:MGI:5614537 NCBI chrNW_004936529:814,649...826,008 JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 ISO (PMID:24475098) ParkinsonsUK-UCL PMID:24475098 NCBI chrNW_004936621:1,573,237...1,578,257 JBrowse link
G Bag6 BAG cochaperone 6 ISO (MGI:MGI:3808636|PMID:18678708) UniProtKB PMID:18678708 MGI:MGI:3808636 NCBI chrNW_004936727:1,866,235...1,885,266 JBrowse link
G Camlg calcium modulating ligand ISO (PMID:20553626) UniProt PMID:20553626 NCBI chrNW_004936597:1,979,029...1,988,281 JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 ISO (PMID:23398316) UniProtKB PMID:23398316 NCBI chrNW_004936555:6,341,455...6,356,677 JBrowse link
G Clec16a C-type lectin domain containing 16A ISO (MGI:MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:MGI:5603233 NCBI chrNW_004936530:9,089,478...9,264,563 JBrowse link
G Ddrgk1 DDRGK domain containing 1 ISO (PMID:28263186) UniProtKB PMID:28263186 NCBI chrNW_004936485:15,516,348...15,526,380 JBrowse link
G Eif3h eukaryotic translation initiation factor 3 subunit H ISO (PMID:32269044) FlyBase PMID:32269044 NCBI chrNW_004936470:29,509,154...29,606,124 JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO (PMID:15313915) UniProtKB PMID:15313915 NCBI chrNW_004936473:397,140...1,424,805 JBrowse link
G Gipc1 GIPC PDZ domain containing family member 1 ISO (MGI:MGI:3807767|PMID:11546783) BHF-UCL PMID:11546783 MGI:MGI:3807767 NCBI chrNW_004936659:3,019,829...3,030,280 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO (PMID:16280321)
(PMID:24613385)
MGI
UniProtKB
PMID:16280321, PMID:24613385 NCBI chrNW_004936476:15,830,459...15,836,994 JBrowse link
G Klhl40 kelch like family member 40 ISO (MGI:MGI:5586592|PMID:24960163) MGI PMID:24960163 MGI:MGI:5586592 NCBI chrNW_004936695:2,417,938...2,424,622 JBrowse link
G Map1a microtubule associated protein 1A ISO (MGI:MGI:5703671|PMID:26609151) ARUK-UCL PMID:26609151 MGI:MGI:5703671 NCBI chrNW_004936471:6,685,565...6,706,860 JBrowse link
G Mtm1 myotubularin 1 ISO (MGI:MGI:5510937|PMID:23695157) MGI PMID:23695157 MGI:MGI:5510937 NCBI chrNW_004936714:1,792,893...1,870,338 JBrowse link
G N4bp1 NEDD4 binding protein 1 ISO (MGI:MGI:3829128|PMID:17592138) UniProtKB PMID:17592138 MGI:MGI:3829128 NCBI chrNW_004936475:1,743,205...1,765,466 JBrowse link
G Nop53 NOP53 ribosome biogenesis factor ISO (PMID:22522597) UniProtKB PMID:22522597 NCBI chrNW_004936664:1,334,487...1,343,867 JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase ISO (PMID:26678539) UniProtKB PMID:26678539 NCBI chrNW_004936762:99,335...137,833 JBrowse link
G Park7 Parkinsonism associated deglycase ISO (PMID:17015834) ParkinsonsUK-UCL PMID:17015834 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
G Pbk PDZ binding kinase ISO (MGI:MGI:5293269|PMID:21715333) MGI PMID:21715333 MGI:MGI:5293269 NCBI chrNW_004936675:704,001...722,769 JBrowse link
G Rpl11 ribosomal protein L11 ISO (MGI:MGI:5897550|PMID:21804542) UniProtKB PMID:21804542 MGI:MGI:5897550 NCBI chrNW_004936474:8,855,782...8,858,287 JBrowse link
G Rybp RING1 and YY1 binding protein ISO (PMID:27060496) UniProtKB PMID:27060496 NCBI chrNW_004936603:3,618,715...3,693,007 JBrowse link
G Sdcbp syndecan binding protein ISO (PMID:25893292) UniProtKB PMID:25893292 NCBI chrNW_004936496:14,331,971...14,347,123 JBrowse link
G Senp1 SUMO specific peptidase 1 ISO (MGI:MGI:3818351|PMID:17981124) MGI PMID:17981124 MGI:MGI:3818351 NCBI chrNW_004936512:5,932,594...5,989,819 JBrowse link
G Shh sonic hedgehog signaling molecule ISO (MGI:MGI:3624046|PMID:16611981) MGI PMID:16611981 MGI:MGI:3624046 NCBI chrNW_004936527:10,033,095...10,042,713 JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 ISO (MGI:MGI:5310666|PMID:22285184) MGI PMID:22285184 MGI:MGI:5310666 NCBI chrNW_004936596:1,257,723...1,407,358 JBrowse link
G Taf9 TATA-box binding protein associated factor 9 ISO (PMID:11278372) BHF-UCL PMID:11278372 NCBI chrNW_004936480:252,435...256,609 JBrowse link
G Tlk2 tousled like kinase 2 ISO (PMID:20016786) UniProtKB PMID:20016786 NCBI chrNW_004936541:3,303,563...3,422,093 JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 ISO (MGI:MGI:6362140|PMID:31537781) MGI PMID:31537781 MGI:MGI:6362140 NCBI chrNW_004936542:3,567,469...3,571,393 JBrowse link
G Ubxn1 UBX domain protein 1 ISO (PMID:20351172) UniProtKB PMID:20351172 NCBI chrNW_004936581:584,519...587,863 JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 ISO (PMID:23770237) UniProtKB PMID:23770237 NCBI chrNW_004936638:1,242,950...1,289,376 JBrowse link
G Usp7 ubiquitin specific peptidase 7 ISO (PMID:26678539) UniProtKB PMID:26678539 NCBI chrNW_004936530:7,693,681...7,724,215 JBrowse link
G Wac WW domain containing adaptor with coiled-coil ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chrNW_004936613:2,793,706...2,862,984 JBrowse link
negative regulation of protein deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 ISO (PMID:15936278) BHF-UCL PMID:15936278 NCBI chrNW_004936569:1,689,926...1,697,179 JBrowse link
G Trim21 tripartite motif containing 21 ISO (PMID:16472766) UniProtKB PMID:16472766 NCBI chrNW_004936498:690,481...697,305 JBrowse link
negative regulation of protein K48-linked deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase ISO (PMID:21097510) ParkinsonsUK-UCL PMID:21097510 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
G Ubxn1 UBX domain protein 1 ISO (PMID:21135095) ParkinsonsUK-UCL PMID:21135095 NCBI chrNW_004936581:584,519...587,863 JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp4 acid phosphatase 4 ISO (PMID:15219672) UniProtKB PMID:15219672 NCBI chrNW_004936889:510,667...515,831 JBrowse link
G Cdh1 cadherin 1 ISO (MGI:MGI:3763814|PMID:17344476) MGI PMID:17344476 MGI:MGI:3763814 NCBI chrNW_004936475:18,990,529...19,065,954 JBrowse link
G Chac1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 ISO (PMID:22445366) UniProtKB PMID:22445366 NCBI chrNW_004936471:4,344,234...4,346,998 JBrowse link
G Fmr1 FMRP translational regulator 1 ISO Casp3 RGD PMID:22817682 RGD:11566024 NCBI chrNW_004936513:1,290,038...1,327,850 JBrowse link
G Glg1 golgi glycoprotein 1 ISO (MGI:MGI:4829577|PMID:20530870) MGI PMID:20530870 MGI:MGI:4829577 NCBI chrNW_004936475:23,411,194...23,534,692 JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO (MGI:MGI:5468848|PMID:23395675) MGI PMID:23395675 MGI:MGI:5468848 NCBI chrNW_004936713:679,680...716,801 JBrowse link
G Lrrk2 leucine rich repeat kinase 2 ISO (PMID:21370995) ParkinsonsUK-UCL PMID:21370995 NCBI chrNW_004936607:628,469...761,117 JBrowse link
G Mdm2 MDM2 proto-oncogene ISO caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chrNW_004936545:6,709,903...6,732,334 JBrowse link
G Ppp1r15a protein phosphatase 1 regulatory subunit 15A ISO Casp3 RGD PMID:21925170 RGD:9999170 NCBI chrNW_004936664:2,910,609...2,914,205 JBrowse link
G Snx12 sorting nexin 12 ISO (PMID:22709416) UniProtKB PMID:22709416 NCBI chrNW_004936762:523,641...534,646 JBrowse link
G Tmem59 transmembrane protein 59 ISO (PMID:20427278) UniProtKB PMID:20427278 NCBI chrNW_004936522:7,105,240...7,126,701 JBrowse link
G Tmem98 transmembrane protein 98 ISO (MGI:MGI:6258499|PMID:30249802) UniProt PMID:30249802 MGI:MGI:6258499 NCBI chrNW_004936538:2,065,663...2,074,678 JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chrNW_004936668:628,875...633,425 JBrowse link
negative regulation of proteolysis involved in cellular protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efna1 ephrin A1 ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chrNW_004936580:4,654,503...4,660,950 JBrowse link
G Epha4 EPH receptor A4 ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chrNW_004936569:3,539,269...3,670,322 JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Styx serine/threonine/tyrosine interacting protein ISO (PMID:28007894) UniProtKB PMID:28007894 NCBI chrNW_004936697:2,087,689...2,120,507 JBrowse link
negative regulation of serine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cr1 complement C3b/C4b receptor 1 (Knops blood group) ISO (PMID:6910481) UniProtKB PMID:6910481 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
G Spink1 serine peptidase inhibitor Kazal type 1 ISO (MGI:MGI:5428115|PMID:22228629)
(MGI:MGI:4442135|PMID:20110462)
MGI
RGD
PMID:12771515, PMID:20110462, PMID:22228629 MGI:MGI:4442135, MGI:MGI:5428115, RGD:724699 NCBI chrNW_004936504:6,975,044...6,981,304 JBrowse link
G Spink2 serine peptidase inhibitor Kazal type 2 ISO (MGI:MGI:5287926|PMID:21705336) MGI PMID:21705336 MGI:MGI:5287926 NCBI chrNW_004936482:18,965,186...18,970,189 JBrowse link
G Spink5 serine peptidase inhibitor Kazal type 5 ISO (MGI:MGI:3770082|PMID:17012259) UniProtKB PMID:17012259 MGI:MGI:3770082 NCBI chrNW_004936504:6,653,703...6,750,110 JBrowse link
negative regulation of serine-type peptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor Kazal type 5 ISO (MGI:MGI:4440399|PMID:20179351) MGI PMID:20179351 MGI:MGI:4440399 NCBI chrNW_004936504:6,653,703...6,750,110 JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A ISO (MGI:MGI:4461099|PMID:20100865) MGI PMID:20100865 MGI:MGI:4461099 NCBI chrNW_004936476:24,093,838...24,200,611 JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chrNW_004936485:17,966,993...18,021,191 JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chrNW_004936475:10,030,408...10,073,576 JBrowse link
G Hfe homeostatic iron regulator ISO (PMID:24904118) BHF-UCL PMID:24904118 NCBI chrNW_004936671:1,940,079...1,947,574 JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 ISO (PMID:21628596) FlyBase PMID:21628596 NCBI chrNW_004936592:3,800,619...3,934,347 JBrowse link
G Pdcl3 phosducin like 3 ISO (PMID:23792958) MGI PMID:23792958 NCBI chrNW_004936661:419,113...428,032 JBrowse link
G Pml PML nuclear body scaffold ISO (PMID:15195100) UniProtKB PMID:15195100 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
G Psen1 presenilin 1 ISO (MGI:MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:MGI:4887523 NCBI chrNW_004936488:2,464,623...2,528,807 JBrowse link
G Psen2 presenilin 2 ISO (MGI:MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:MGI:4887523 NCBI chrNW_004936526:3,584,194...3,611,719 JBrowse link
G Qrich2 glutamine rich 2 ISO (MGI:MGI:6277293|PMID:30683861)
(PMID:30683861)
UniProt PMID:30683861 MGI:MGI:6277293 NCBI chrNW_004936594:1,383,332...1,423,961 JBrowse link
G Rpl11 ribosomal protein L11 ISO (PMID:18560357) CAFA PMID:18560357 NCBI chrNW_004936474:8,855,782...8,858,287 JBrowse link
G Rpl23 ribosomal protein L23 ISO (PMID:15314173) CAFA PMID:15314173 NCBI chrNW_004936490:14,240,635...14,245,194 JBrowse link
G Rpl5 ribosomal protein L5 ISO (PMID:18560357) CAFA PMID:18560357 NCBI chrNW_004936537:6,341,961...6,344,831 JBrowse link
G Rps7 ribosomal protein S7 ISO (PMID:17310983) CAFA PMID:17310983 NCBI chrNW_004936532:1,734,993...1,740,202 JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat containing alpha ISO (PMID:23129660) UniProtKB PMID:23129660 NCBI chrNW_004936588:1,599,453...1,616,480 JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO (MGI:MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:MGI:4355593 NCBI chrNW_004936600:3,270,662...3,381,722 JBrowse link
G Taf1 TATA-box binding protein associated factor 1 ISO (PMID:17237821) ParkinsonsUK-UCL PMID:17237821 NCBI chrNW_004936762:189,710...271,759 JBrowse link
G Wnt1 Wnt family member 1 ISO (MGI:MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:MGI:3628833 NCBI chrNW_004936512:6,781,001...6,785,358 JBrowse link
negative regulation of ubiquitin-specific protease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase ISO (PMID:21097510) ParkinsonsUK-UCL PMID:21097510 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
G Ubxn1 UBX domain protein 1 ISO (PMID:21135095) ParkinsonsUK-UCL PMID:21135095 NCBI chrNW_004936581:584,519...587,863 JBrowse link
zymogen inhibition term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin, paired basic amino acid cleaving enzyme ISO (PMID:11799113), (PMID:9130696) UniProt PMID:9130696, PMID:11799113 NCBI chrNW_004936483:16,136,099...16,147,945 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12001
    metabolic process 7670
      primary metabolic process 6812
        protein metabolic process 3916
          proteolysis 1068
            negative regulation of proteolysis 209
              negative regulation of membrane protein ectodomain proteolysis 5
              negative regulation of peptidase activity + 108
              negative regulation of protein desumoylation 0
              negative regulation of protein deubiquitination + 4
              negative regulation of protein processing + 26
              negative regulation of proteolysis involved in cellular protein catabolic process + 66
Path 2
Term Annotations click to browse term
  biological_process 12001
    metabolic process 7670
      organic substance metabolic process 7376
        macromolecule metabolic process 6395
          protein metabolic process 3916
            cellular protein metabolic process 3540
              regulation of cellular protein metabolic process 2170
                negative regulation of cellular protein metabolic process 830
                  negative regulation of proteolysis 209
                    negative regulation of membrane protein ectodomain proteolysis 5
                    negative regulation of peptidase activity + 108
                    negative regulation of protein desumoylation 0
                    negative regulation of protein deubiquitination + 4
                    negative regulation of protein processing + 26
                    negative regulation of proteolysis involved in cellular protein catabolic process + 66
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.