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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of smoothened signaling pathway
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Accession:GO:0045880 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of smoothened signaling.
Synonyms:exact_synonym: positive regulation of hedgehog signaling pathway;   positive regulation of hh signaling pathway;   positive regulation of smoothened signalling pathway;   up regulation of smoothened signaling pathway;   upregulation of smoothened signaling pathway
 narrow_synonym: activation of smoothened signaling pathway;   stimulation of smoothened signaling pathway
 related_synonym: positive regulation of smoothened by patched;   positive regulation of smoothened receptor activity by patched
 alt_id: GO:0045878


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positive regulation of smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Armc9 armadillo repeat containing 9 JBrowse link 9 93,172,718 93,299,119 RGD:1600115
RGD:1624291
G Chsy1 chondroitin sulfate synthase 1 JBrowse link 1 127,010,587 127,071,570 RGD:1624291
G Cibar1 CBY1 interacting BAR domain containing 1 JBrowse link 5 25,732,457 25,750,953 RGD:1624291
G Ctnna1 catenin alpha 1 JBrowse link 18 27,923,229 28,055,972 RGD:1624291
G Dcdc2 doublecortin domain containing 2 JBrowse link 17 41,838,201 42,031,265 RGD:1624291
G Dlg5 discs large MAGUK scaffold protein 5 JBrowse link 15 120,213 230,312 RGD:1624291
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 JBrowse link 8 5,217,054 5,436,969 RGD:1624291
RGD:1600115
G Evc EvC ciliary complex subunit 1 JBrowse link 14 78,213,601 78,253,266 RGD:1624291
G Fgf9 fibroblast growth factor 9 JBrowse link 15 38,341,657 38,386,945 RGD:1624291
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
G Gas1 growth arrest-specific 1 JBrowse link 17 4,846,116 4,849,350 RGD:1624291
G Gas8 growth arrest specific 8 JBrowse link 19 56,316,367 56,335,873 RGD:1600115
RGD:1624291
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:1624291
G Gpc3 glypican 3 JBrowse link X 139,579,268 139,947,093 RGD:1624291
RGD:1600115
G Ift172 intraflagellar transport 172 JBrowse link 6 26,390,686 26,485,459 RGD:1624291
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1624291
G Intu inturned planar cell polarity protein JBrowse link 2 127,589,325 127,611,705 RGD:1624291
RGD:1600115
G Kif7 kinesin family member 7 JBrowse link 1 141,434,183 141,452,592 RGD:1624291
G Ndst1 N-deacetylase and N-sulfotransferase 1 JBrowse link 18 55,951,497 56,014,107 RGD:1624291
G Pdcl phosducin-like JBrowse link 3 21,602,349 21,609,821 RGD:1600115
RGD:1624291
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:2316785
G Prrx1 paired related homeobox 1 JBrowse link 13 81,147,038 81,215,559 RGD:1624291
G Prrx2 paired related homeobox 2 JBrowse link 3 9,681,871 9,718,051 RGD:1624291
G Rab34 RAB34, member RAS oncogene family JBrowse link 10 65,448,111 65,452,178 RGD:1600115
RGD:1624291
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 JBrowse link 7 124,501,988 124,620,755 RGD:1624291
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 JBrowse link 1 174,428,056 174,495,356 RGD:1624291
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 JBrowse link 20 7,718,260 7,749,847 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Shox2 short stature homeobox 2 JBrowse link 2 164,118,175 164,126,783 RGD:1624291
G Skor2 SKI family transcriptional corepressor 2 JBrowse link 18 73,145,596 73,199,395 RGD:1624291
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:13792537
RGD:1600115
G Stk36 serine/threonine kinase 36 JBrowse link 9 81,880,175 81,908,014 RGD:1624291
G Tedc1 tubulin epsilon and delta complex 1 JBrowse link 6 137,967,119 137,976,324 RGD:1624291
G Tedc2 tubulin epsilon and delta complex 2 JBrowse link 10 13,586,852 13,591,938 RGD:1624291
G Ttc23 tetratricopeptide repeat domain 23 JBrowse link 1 128,604,324 128,687,900 RGD:1600115
RGD:1624291
G Tubd1 tubulin, delta 1 JBrowse link 10 73,865,828 73,886,976 RGD:1624291
G Txndc15 thioredoxin domain containing 15 JBrowse link 17 9,429,171 9,441,628 RGD:1600115
RGD:1624291
G Uchl5 ubiquitin C-terminal hydrolase L5 JBrowse link 13 60,568,102 60,603,812 RGD:1624291
G Ulk3 unc-51 like kinase 3 JBrowse link 8 62,368,548 62,375,229 RGD:1600115
RGD:1624291
G Wnt9a Wnt family member 9A JBrowse link 10 45,659,045 45,686,103 RGD:1624291
positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gorab golgin, RAB6-interacting JBrowse link 13 81,682,207 81,698,827 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    cellular process 18361
      signal transduction 6929
        positive regulation of signal transduction 1625
          positive regulation of smoothened signaling pathway 43
            positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1
Path 2
Term Annotations click to browse term
  biological_process 19576
    biological regulation 13536
      regulation of biological process 12839
        regulation of cellular process 12332
          signal transduction 6929
            cell surface receptor signaling pathway 2716
              smoothened signaling pathway 160
                regulation of smoothened signaling pathway 93
                  positive regulation of smoothened signaling pathway 43
                    positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.