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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of smoothened signaling pathway
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Accession:GO:0045880 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of smoothened signaling.
Synonyms:exact_synonym: positive regulation of hedgehog signaling pathway;   positive regulation of hh signaling pathway;   positive regulation of smoothened signalling pathway;   up regulation of smoothened signaling pathway;   upregulation of smoothened signaling pathway
 narrow_synonym: activation of smoothened signaling pathway;   stimulation of smoothened signaling pathway
 related_synonym: positive regulation of smoothened by patched;   positive regulation of smoothened receptor activity by patched
 alt_id: GO:0045878


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positive regulation of smoothened signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARMC9 armadillo repeat containing 9 JBrowse link 2 231,198,628 231,394,991 RGD:2290271
G CHSY1 chondroitin sulfate synthase 1 JBrowse link 15 101,175,727 101,252,048 RGD:2290271
G CIBAR1 CBY1 interacting BAR domain containing 1 JBrowse link 8 93,700,550 93,731,527 RGD:2290271
G CTNNA1 catenin alpha 1 JBrowse link 5 138,753,386 138,935,034 RGD:2290271
G DCDC2 doublecortin domain containing 2 JBrowse link 6 24,171,755 24,383,292 RGD:2290271
G DLG5 discs large MAGUK scaffold protein 5 JBrowse link 10 77,790,787 77,926,755 RGD:2290271
G DYNC2H1 dynein cytoplasmic 2 heavy chain 1 JBrowse link 11 103,109,426 103,479,863 RGD:2290271
G EVC EvC ciliary complex subunit 1 JBrowse link 4 5,711,199 5,829,043 RGD:2290271
G FGF9 fibroblast growth factor 9 JBrowse link 13 21,671,073 21,704,501 RGD:2290271
G FOXA1 forkhead box A1 JBrowse link 14 37,589,552 37,595,249 RGD:2290271
G GAS8 growth arrest specific 8 JBrowse link 16 90,019,629 90,044,971 RGD:2290271
G GLI1 GLI family zinc finger 1 JBrowse link 12 57,459,785 57,472,451 RGD:2290271
G GPC3 glypican 3 JBrowse link X 133,535,745 133,985,616 RGD:2290271
G IFT172 intraflagellar transport 172 JBrowse link 2 27,444,373 27,489,819 RGD:2290271
G IHH Indian hedgehog signaling molecule JBrowse link 2 219,054,424 219,060,921 RGD:2290271
G INTU inturned planar cell polarity protein JBrowse link 4 127,623,271 127,726,737 RGD:2290271
G KIF7 kinesin family member 7 JBrowse link 15 89,627,977 89,663,086 RGD:2290271
G NDST1 N-deacetylase and N-sulfotransferase 1 JBrowse link 5 150,497,779 150,558,211 RGD:2290271
G PDCL phosducin like JBrowse link 9 122,818,097 122,828,588 RGD:2290271
G POR cytochrome p450 oxidoreductase JBrowse link 7 75,915,155 75,986,855 RGD:2290271
G PRRX1 paired related homeobox 1 JBrowse link 1 170,662,728 170,739,421 RGD:2290271
G RAB34 RAB34, member RAS oncogene family JBrowse link 17 28,714,281 28,718,440 RGD:2290271
G SCUBE1 signal peptide, CUB domain and EGF like domain containing 1 JBrowse link 22 43,197,280 43,343,372 RGD:2290271
G SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 JBrowse link 6 35,213,956 35,253,079 RGD:2290271
G SFRP1 secreted frizzled related protein 1 JBrowse link 8 41,261,962 41,309,473 RGD:2290271
G SHH sonic hedgehog signaling molecule JBrowse link 7 155,799,980 155,812,463 RGD:2290271
G SHOX2 short stature homeobox 2 JBrowse link 3 158,095,905 158,106,420 RGD:2290271
G SKOR2 SKI family transcriptional corepressor 2 JBrowse link 18 47,206,169 47,251,660 RGD:2290271
G SMO smoothened, frizzled class receptor JBrowse link 7 129,188,633 129,213,548 RGD:2290271
G STK36 serine/threonine kinase 36 JBrowse link 2 218,672,049 218,702,717 RGD:2290271
G TEDC1 tubulin epsilon and delta complex 1 JBrowse link 14 105,489,855 105,499,248 RGD:2290271
G TEDC2 tubulin epsilon and delta complex 2 JBrowse link 16 2,460,109 2,464,963 RGD:2290271
G TTC23 tetratricopeptide repeat domain 23 JBrowse link 15 99,136,323 99,251,226 RGD:2290271
G TUBD1 tubulin delta 1 JBrowse link 17 59,859,467 59,892,948 RGD:2290271
G TXNDC15 thioredoxin domain containing 15 JBrowse link 5 134,873,770 134,901,635 RGD:2290271
G ULK3 unc-51 like kinase 3 JBrowse link 15 74,836,118 74,843,166 RGD:2290271
G WNT9A Wnt family member 9A JBrowse link 1 227,918,656 227,947,932 RGD:2290271
patched ligand maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DISP1 dispatched RND transporter family member 1 JBrowse link 1 222,814,514 223,005,995 RGD:2290271
positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GORAB golgin, RAB6 interacting JBrowse link 1 170,532,134 170,553,834 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18019
    cellular process 16998
      signal transduction 6313
        positive regulation of signal transduction 1719
          positive regulation of smoothened signaling pathway 39
            patched ligand maturation 1
            positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1
Path 2
Term Annotations click to browse term
  biological_process 18019
    biological regulation 12659
      regulation of biological process 11961
        regulation of cellular process 11416
          signal transduction 6313
            cell surface receptor signaling pathway 3214
              smoothened signaling pathway 147
                regulation of smoothened signaling pathway 88
                  positive regulation of smoothened signaling pathway 39
                    patched ligand maturation 1
                    positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.