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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA recombination
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Accession:GO:0045910 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.
Synonyms:exact_synonym: down regulation of DNA recombination;   downregulation of DNA recombination
 narrow_synonym: inhibition of DNA recombination


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negative regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G H1f0 H1 histone family, member 0 JBrowse link 7 120,260,776 120,262,636 RGD:13792537
G H1f1 H1.1 linker histone, cluster member JBrowse link 17 43,614,101 43,614,844 RGD:13792537
G H1f10 H1.10 linker histone JBrowse link 4 119,889,016 119,892,661 RGD:13792537
G H1f2 H1.2 linker histone, cluster member JBrowse link 17 43,638,938 43,640,445 RGD:13792537
G H1f4 H1.4 linker histone, cluster member JBrowse link 17 43,734,461 43,735,120 RGD:13792537
G H1f5 H1.5 linker histone, cluster member JBrowse link 17 44,766,313 44,766,981 RGD:13792537
G H1f6 H1.6 linker histone, cluster member JBrowse link 17 43,675,190 43,675,934 RGD:13792537
G H1f7 H1.7 linker histone JBrowse link 7 139,871,491 139,872,858 RGD:13792537
G H1f8 H1.8 linker histone JBrowse link 4 147,844,658 147,849,779 RGD:13792537
G H4f3 H1.3 linker histone, cluster member JBrowse link 17 43,797,711 43,798,450 RGD:13792537
G Hils1 histone linker H1 domain, spermatid-specific 1 JBrowse link 10 82,775,691 82,776,487 RGD:13792537
G Lig3 DNA ligase 3 JBrowse link 10 70,134,734 70,158,051 RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1624291
RGD:13792537
RGD:1600115
G Msh3 mutS homolog 3 JBrowse link 2 21,790,048 21,931,791 RGD:1624291
G Msh6 mutS homolog 6 JBrowse link 6 11,644,565 11,662,389 RGD:1624291
RGD:13792537
G Rad18 RAD18 E3 ubiquitin protein ligase JBrowse link 4 144,537,329 144,620,606 RGD:1624291
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
RGD:13792537
G Zranb3 zinc finger RANBP2-type containing 3 JBrowse link 13 44,661,375 44,812,430 RGD:1624291
negative regulation of DNA recombination at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pot1b protection of telomeres 1B JBrowse link 9 7,845,697 7,902,270 RGD:1600115
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1600115
RGD:1624291
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cgas cyclic GMP-AMP synthase JBrowse link 8 85,789,515 85,804,008 RGD:1624291
RGD:13792537
G Fancb FA complementation group B JBrowse link X 31,124,018 31,140,790 RGD:1624291
RGD:13792537
G Fbh1 F-box DNA helicase 1 JBrowse link 17 70,399,093 70,437,151 RGD:1624291
G Helb DNA helicase B JBrowse link 7 64,860,641 64,888,146 RGD:1624291
RGD:13792537
G Klhl15 kelch-like family member 15 JBrowse link X 63,342,277 63,390,915 RGD:1624291
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link 5 164,943,183 164,956,255 RGD:1624291
G Parpbp PARP1 binding protein JBrowse link 7 28,654,707 28,724,412 RGD:1624291
RGD:1600115
G Polq DNA polymerase theta JBrowse link 11 66,585,860 66,695,369 RGD:1624291
G Radx RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 110,670,037 110,782,420 RGD:1624291
RGD:1600115
G Recql5 RecQ like helicase 5 JBrowse link 10 104,443,735 104,482,889 RGD:1624291
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
G Rmi2 RecQ mediated genome instability 2 JBrowse link 10 4,904,458 4,910,339 RGD:13792537
G Shld1 shieldin complex subunit 1 JBrowse link 3 125,318,682 125,396,705 RGD:1624291
RGD:13792537
G Shld2 shieldin complex subunit 2 JBrowse link 16 10,570,307 10,661,528 RGD:1624291
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 9 119,675,750 119,818,620 RGD:1624291
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link 3 113,160,030 113,259,701 RGD:1624291
G Ubqln4 ubiquilin 4 JBrowse link 2 187,915,701 187,931,035 RGD:1624291
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1624291
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
negative regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankle1 ankyrin repeat and LEM domain containing 1 JBrowse link 16 19,799,943 19,826,057 RGD:1624291
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1624291
RGD:1600115
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      negative regulation of metabolic process 3072
        negative regulation of macromolecule metabolic process 2787
          negative regulation of DNA metabolic process 130
            negative regulation of DNA recombination 47
              inactivation of recombination (HML) 0
              negative regulation of DNA recombination at centromere 0
              negative regulation of DNA recombination at telomere + 3
              negative regulation of double-strand break repair via homologous recombination + 17
              negative regulation of isotype switching + 6
              negative regulation of mitotic recombination + 4
              negative regulation of reciprocal meiotic recombination + 0
              negative regulation of single-strand break repair via homologous recombination 0
              negative regulation of strand invasion 0
              negative regulation of transposition, DNA-mediated 0
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      cellular metabolic process 10639
        cellular aromatic compound metabolic process 5503
          nucleobase-containing compound metabolic process 5274
            nucleic acid metabolic process 4784
              DNA metabolic process 885
                DNA recombination 307
                  regulation of DNA recombination 107
                    negative regulation of DNA recombination 47
                      inactivation of recombination (HML) 0
                      negative regulation of DNA recombination at centromere 0
                      negative regulation of DNA recombination at telomere + 3
                      negative regulation of double-strand break repair via homologous recombination + 17
                      negative regulation of isotype switching + 6
                      negative regulation of mitotic recombination + 4
                      negative regulation of reciprocal meiotic recombination + 0
                      negative regulation of single-strand break repair via homologous recombination 0
                      negative regulation of strand invasion 0
                      negative regulation of transposition, DNA-mediated 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.