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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA recombination
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Accession:GO:0045910 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.
Synonyms:exact_synonym: down regulation of DNA recombination;   downregulation of DNA recombination
 narrow_synonym: inhibition of DNA recombination


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negative regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BLM BLM RecQ like helicase JBrowse link 7 53,317,515 53,412,649 RGD:14298760
G H1-3 H1.3 linker histone, cluster member RGD:14298760
G H1-4 H1.4 linker histone, cluster member RGD:14298760
G H1-6 H1.6 linker histone, cluster member JBrowse link 7 20,774,135 20,777,244 RGD:14298760
G H1FOO oocyte-specific H1 histone JBrowse link 13 68,921,491 68,943,061 RGD:14298760
G LOC100510904 histone H1.0 JBrowse link 5 10,038,944 10,041,242 RGD:14298760
G LOC100516553 testis-specific H1 histone JBrowse link 5 78,699,291 78,700,227 RGD:14298760
G MSH2 mutS homolog 2 JBrowse link 3 93,082,958 93,163,556 RGD:14298760
G MSH3 mutS homolog 3 JBrowse link 2 89,255,647 89,456,102 RGD:14298760
G MSH6 mutS homolog 6 JBrowse link 3 92,792,590 92,814,154 RGD:14298760
G RTEL1 regulator of telomere elongation helicase 1 JBrowse link 17 62,611,844 62,636,628 RGD:14298760
G ZRANB3 zinc finger RANBP2-type containing 3 JBrowse link 15 16,414,291 16,727,659 RGD:14298760
negative regulation of DNA recombination at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERF2IP TERF2 interacting protein JBrowse link 6 12,047,409 12,057,451 RGD:14298760
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CGAS cyclic GMP-AMP synthase JBrowse link 1 92,483,253 92,500,376 RGD:14298760
G FANCB FA complementation group B JBrowse link X 11,386,360 11,408,958 RGD:14298760
G FBH1 F-box DNA helicase 1 JBrowse link 10 65,060,714 65,108,975 RGD:14298760
G HELB DNA helicase B JBrowse link 5 30,645,378 30,696,488 RGD:14298760
G KLHL15 kelch like family member 15 JBrowse link X 20,088,208 20,130,452 RGD:14298760
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 6 71,773,680 71,779,192 RGD:14298760
G MAGEF1 MAGE family member F1 JBrowse link 13 122,600,984 122,602,700 RGD:14298760
G PARPBP PARP1 binding protein JBrowse link 5 82,018,857 82,091,946 RGD:14298760
G POLQ DNA polymerase theta JBrowse link 13 138,962,634 139,108,499 RGD:14298760
G RADX RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 87,025,603 87,103,503 RGD:14298760
G RECQL5 RecQ like helicase 5 JBrowse link 12 5,732,336 5,770,136 RGD:14298760
G RIF1 replication timing regulatory factor 1 JBrowse link 15 769,518 832,036 RGD:14298760
G RMI2 RecQ mediated genome instability 2 JBrowse link 3 31,807,717 31,814,869 RGD:14298760
G SHLD1 shieldin complex subunit 1 JBrowse link 17 14,610,723 14,706,082 RGD:14298760
G SHLD2 shieldin complex subunit 2 JBrowse link 14 88,005,599 88,121,155 RGD:14298760
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 6 103,809,732 103,986,057 RGD:14298760
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 1 127,958,500 128,032,370 RGD:14298760
G UBQLN4 ubiquilin 4 JBrowse link 4 93,976,386 93,994,830 RGD:14298760
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARP3 poly(ADP-ribose) polymerase family member 3 JBrowse link 13 34,075,807 34,084,384 RGD:14298760
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 13 125,377,247 125,401,328 RGD:14298760
G FOXP3 forkhead box P3 JBrowse link X 43,303,777 43,328,164 RGD:14298760
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 2 143,688,946 143,734,523 RGD:14298760
negative regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANKLE1 ankyrin repeat and LEM domain containing 1 JBrowse link 2 60,391,110 60,397,559 RGD:14298760
G MLH1 mutL homolog 1 JBrowse link 13 21,791,276 21,877,789 RGD:14298760
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERF2 telomeric repeat binding factor 2 JBrowse link 6 17,605,748 17,631,795 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15162
    metabolic process 9321
      negative regulation of metabolic process 2213
        negative regulation of macromolecule metabolic process 2046
          negative regulation of DNA metabolic process 83
            negative regulation of DNA recombination 38
              inactivation of recombination (HML) 0
              negative regulation of DNA recombination at centromere 0
              negative regulation of DNA recombination at telomere + 2
              negative regulation of double-strand break repair via homologous recombination + 18
              negative regulation of isotype switching + 4
              negative regulation of mitotic recombination + 3
              negative regulation of reciprocal meiotic recombination + 0
              negative regulation of single-strand break repair via homologous recombination 0
              negative regulation of strand invasion 0
              negative regulation of transposition, DNA-mediated 0
Path 2
Term Annotations click to browse term
  biological_process 15162
    metabolic process 9321
      cellular metabolic process 8405
        cellular aromatic compound metabolic process 4363
          nucleobase-containing compound metabolic process 4222
            nucleic acid metabolic process 3865
              DNA metabolic process 659
                DNA recombination 229
                  regulation of DNA recombination 85
                    negative regulation of DNA recombination 38
                      inactivation of recombination (HML) 0
                      negative regulation of DNA recombination at centromere 0
                      negative regulation of DNA recombination at telomere + 2
                      negative regulation of double-strand break repair via homologous recombination + 18
                      negative regulation of isotype switching + 4
                      negative regulation of mitotic recombination + 3
                      negative regulation of reciprocal meiotic recombination + 0
                      negative regulation of single-strand break repair via homologous recombination 0
                      negative regulation of strand invasion 0
                      negative regulation of transposition, DNA-mediated 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.