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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of complement activation
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Accession:GO:0045916 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation.
Synonyms:exact_synonym: down regulation of complement activation;   downregulation of complement activation;   negative regulation of complement cascade
 narrow_synonym: inhibition of complement activation


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negative regulation of complement activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:2293559
G Cd55 CD55 molecule (Cromer blood group) JBrowse link 13 47,125,156 47,153,557 RGD:2326180
RGD:1624291
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:1624291
G Cr1l complement C3b/C4b receptor 1 like JBrowse link 13 113,824,886 113,872,097 RGD:625470
RGD:1624291
G Masp1 mannan-binding lectin serine peptidase 1 JBrowse link 11 80,736,424 80,806,278 RGD:1624291
negative regulation of activation of membrane attack complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:1600482
RGD:13792537
RGD:1624291
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Susd4 sushi domain containing 4 JBrowse link 13 101,181,932 101,307,912 RGD:1624291
G Vsig4 V-set and immunoglobulin domain containing 4 JBrowse link X 65,370,851 65,400,298 RGD:1624291
RGD:13792537
negative regulation of complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C4bpa complement component 4 binding protein, alpha JBrowse link 13 47,342,090 47,377,580 RGD:1624291
RGD:1600115
G C4bpb complement component 4 binding protein, beta JBrowse link 13 47,387,173 47,398,115 RGD:1624291
RGD:1600115
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Susd4 sushi domain containing 4 JBrowse link 13 101,181,932 101,307,912 RGD:1624291
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 4 154,309,426 154,359,138 RGD:1624291
G Serping1 serpin family G member 1 JBrowse link 3 72,161,230 72,171,109 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    immune system process 2611
      immune effector process 823
        negative regulation of immune effector process 139
          negative regulation of complement activation 11
            negative regulation of activation of membrane attack complex 1
            negative regulation of complement activation, alternative pathway + 3
            negative regulation of complement activation, classical pathway + 4
            negative regulation of complement activation, lectin pathway + 2
            suppression by virus of host complement activation 0
Path 2
Term Annotations click to browse term
  biological_process 19336
    biological regulation 13340
      regulation of biological process 12655
        positive regulation of biological process 6411
          positive regulation of immune system process 978
            positive regulation of immune response 608
              activation of immune response 386
                complement activation 149
                  regulation of complement activation 20
                    negative regulation of complement activation 11
                      negative regulation of activation of membrane attack complex 1
                      negative regulation of complement activation, alternative pathway + 3
                      negative regulation of complement activation, classical pathway + 4
                      negative regulation of complement activation, lectin pathway + 2
                      suppression by virus of host complement activation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.